GEO DataSets

Analysis of oral squamous cell carcinoma (OSCC) cell lines: OC3, SAS, SCC-15, and HSC3, treated with 5-aza-2’-deoxycytidine (AzC), an inhibitor of DNA methyltransferase. Results provide insight into potential tumor suppressor genes silenced by DNA hypermethylation in OSCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent, 4 cell line sets

Platform:

GPL6883

Series:

GSE38823

16 Samples

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Analysis of PC3 prostate cancer cells expressing G-protein coupled receptor kinase 3 (GRK3). Results provide insight into the role of GRK3 in prostate cancer progression and metastasis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL6883

Series:

GSE36022

6 Samples

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Analysis of Huh7 and HepG2 hepatocellular carcinoma (HCC) cells depleted for CSN5, the fifth subunit of the COP9 signalosome. CSN5 expression is elevated in early HCC. Result provide insight into the role of CSN5 in the pathogenesis of HCC.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 cell line, 2 protocol sets

Platform:

GPL6883

Series:

GSE26485

16 Samples

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Analysis of peripheral blood leukocytes and placenta of pregnant smokers. Umbilical cord blood leukocytes of their newborns also examined. Maternal smoking has a negative effect on all stages of pregnancy. Results provide insight into molecular mechanisms underlying tobacco smoke-related defects.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 2 disease state, 3 specimen sets

Platform:

GPL6883

Series:

GSE27272

183 Samples

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Analysis of PBMCs from chronically lonely, older adults. Lack of close social ties is a well-established risk factor for diseases involving the immune system and inflammation. Results provide insight into the molecular mechanisms underlying those effects.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 individual sets

Platform:

GPL6883

Series:

GSE25837

93 Samples

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Analysis of blood after an overnight fast from Impaired Fasting Glucose, commonly called pre-diabetes, and Type 2 Diabetes mellitus (T2D) male patients. These results, together with miRNA profiling, provide insight into the mechanisms underlying the transition from pre-diabetes to overt T2D.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL6883

Series:

GSE26168

24 Samples

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Analysis of Huh7, HepG2, and Hep3B hepatocellular carcinoma (HCC) cells depleted for the ubiquitin modulator COP1. COP1 regulates p53 activity by ubiquitination. p53 is wild type in HepG2, mutated in Huh7, and lacking in Hep3B. Results provide insight into the role of COP1 in HCC pathogenesis.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 cell line, 2 protocol sets

Platform:

GPL6883

Series:

GSE21955

22 Samples

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Analysis of Jurkat T cells exposed to to 0.2 mg/L of silver nanoparticles (AgNPs) and Ag ions for 24 hours. Cell viability screening revealed that Jurkat T cells exhibit higher sensitivity to AgNPs than to Ag ions. Results provide insight into the molecular basis of this difference in sensitivity.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 3 stress sets

Platform:

GPL6883

Series:

GSE20692

9 Samples

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