Analysis of blood after an overnight fast from Impaired Fasting Glucose, commonly called pre-diabetes, and Type 2 Diabetes mellitus (T2D) male patients. These results, together with miRNA profiling, provide insight into the mechanisms underlying the transition from pre-diabetes to overt T2D.
Karolina DS, Armugam A, Tavintharan S, Wong MT et al. MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus. PLoS One 2011;6(8):e22839. PMID: 21829658