Analysis of peripheral blood leukocytes and placenta of pregnant smokers. Umbilical cord blood leukocytes of their newborns also examined. Maternal smoking has a negative effect on all stages of pregnancy. Results provide insight into molecular mechanisms underlying tobacco smoke-related defects.
Votavova H, Dostalova Merkerova M, Fejglova K, Vasikova A et al. Transcriptome alterations in maternal and fetal cells induced by tobacco smoke. Placenta 2011 Oct;32(10):763-70. PMID: 21803418