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Soft Tissue Angiosarcoma

MedGen UID:
891248
•Concept ID:
C4055466
•
Neoplastic Process
Synonym: Angiosarcoma of Soft Tissue

Definition

An angiosarcoma that arises from the soft tissues, usually in the deep muscles of the lower extremities, retroperitoneum, mediastinum, and mesentery. [from NCI]

Professional guidelines

PubMed

Current topics and management of head and neck sarcomas.
Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A
Jpn J Clin Oncol 2023 Aug 30;53(9):743-756. doi: 10.1093/jjco/hyad048. PMID: 37309253Free PMC Article
Management of Skin Sarcomas.
Messina V, Cope B, Keung EZ, Fiore M
Surg Oncol Clin N Am 2022 Jul;31(3):511-525. Epub 2022 May 31 doi: 10.1016/j.soc.2022.03.010. PMID: 35715147
Management of Vascular Sarcoma.
Subramaniam A, Giani C, Napolitano A, Ravi V, Frezza AM, Jones RL
Surg Oncol Clin N Am 2022 Jul;31(3):485-510. doi: 10.1016/j.soc.2022.03.014. PMID: 35715146

Recent clinical studies

Etiology

Neoadjuvant radiation for cutaneous and soft tissue angiosarcoma.
Sharon CE, Straker RJ, Shannon AB, Shabason JE, Zhang PJL, Fraker DL, Miura JT, Karakousis GC
J Surg Oncol 2022 Mar;125(3):509-515. Epub 2021 Oct 24 doi: 10.1002/jso.26727. PMID: 34689338
Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma.
Mao J, Hu J, Chen Y, Li Y, Run X
J Dermatolog Treat 2022 Aug;33(5):2466-2474. Epub 2021 Aug 24 doi: 10.1080/09546634.2021.1968333. PMID: 34429003
Soft tissue angiosarcoma of the breast in a patient with Klippel-Trenaunay-Weber syndrome.
Bugarin-Estrada E, Villanueva-Castro E, Medina-Franco H
Cir Cir 2018;86(6):566-569. doi: 10.24875/CIRU.18000306. PMID: 30361716
Investigation of Prognostic Features in Primary Cutaneous and Soft Tissue Angiosarcoma After Surgical Resection: A Retrospective Study.
Lee BL, Chen CF, Chen PC, Lee HC, Liao WC, Perng CK, Ma H, Lin CH
Ann Plast Surg 2017 Mar;78(3 Suppl 2):S41-S46. doi: 10.1097/SAP.0000000000001004. PMID: 28118230
Angiosarcoma of skin and soft tissue: a study of forty-four cases.
Maddox JC, Evans HL
Cancer 1981 Oct 15;48(8):1907-21. doi: 10.1002/1097-0142(19811015)48:8<1907::aid-cncr2820480832>3.0.co;2-t. PMID: 7197190

Diagnosis

Ovarian epithelioid angiosarcoma complicating pregnancy: a case report and review of the literature.
Peng X, Duan Z, Yin H, Dai F, Liu H
J Int Med Res 2021 May;49(5):3000605211019641. doi: 10.1177/03000605211019641. PMID: 34039070Free PMC Article
Soft tissue angiosarcoma of the breast in a patient with Klippel-Trenaunay-Weber syndrome.
Bugarin-Estrada E, Villanueva-Castro E, Medina-Franco H
Cir Cir 2018;86(6):566-569. doi: 10.24875/CIRU.18000306. PMID: 30361716
Investigation of Prognostic Features in Primary Cutaneous and Soft Tissue Angiosarcoma After Surgical Resection: A Retrospective Study.
Lee BL, Chen CF, Chen PC, Lee HC, Liao WC, Perng CK, Ma H, Lin CH
Ann Plast Surg 2017 Mar;78(3 Suppl 2):S41-S46. doi: 10.1097/SAP.0000000000001004. PMID: 28118230
Clinicopathologic and immunohistochemical characteristics of adult primary cardiac angiosarcomas: analysis of 10 cases.
Ge Y, Ro JY, Kim D, Kim CH, Reardon MJ, Blackmon S, Zhai J, Coffey D, Benjamin RS, Ayala AG
Ann Diagn Pathol 2011 Aug;15(4):262-7. Epub 2011 May 4 doi: 10.1016/j.anndiagpath.2011.02.007. PMID: 21546292
Hepatic metastases of soft tissue angiosarcoma: CT and MR imaging findings.
Tateishi U, Hasegawa T, Muramatsu Y, Moriyama N
Abdom Imaging 2003 Sep-Oct;28(5):660-4. doi: 10.1007/s00261-003-0008-z. PMID: 14628871

Therapy

Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma.
Mao J, Hu J, Chen Y, Li Y, Run X
J Dermatolog Treat 2022 Aug;33(5):2466-2474. Epub 2021 Aug 24 doi: 10.1080/09546634.2021.1968333. PMID: 34429003
Neoadjuvant chemotherapy for primary cutaneous/soft tissue angiosarcoma: Determining tumor behavior prior to surgical resection.
Oxenberg J, Khushalani NI, Salerno KE, Attwood K, Kane JM 3rd
J Surg Oncol 2015 Jun;111(7):829-33. Epub 2015 Mar 13 doi: 10.1002/jso.23891. PMID: 25772798
Groin angiosarcoma following radiotherapy for vulvar cancer.
Sanz C, Moreno F, Armas A, Casado A, Castillo MC
Gynecol Oncol 2005 May;97(2):677-80. doi: 10.1016/j.ygyno.2004.12.061. PMID: 15863181

Prognosis

Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma.
Mao J, Hu J, Chen Y, Li Y, Run X
J Dermatolog Treat 2022 Aug;33(5):2466-2474. Epub 2021 Aug 24 doi: 10.1080/09546634.2021.1968333. PMID: 34429003
Ovarian epithelioid angiosarcoma complicating pregnancy: a case report and review of the literature.
Peng X, Duan Z, Yin H, Dai F, Liu H
J Int Med Res 2021 May;49(5):3000605211019641. doi: 10.1177/03000605211019641. PMID: 34039070Free PMC Article
Investigation of Prognostic Features in Primary Cutaneous and Soft Tissue Angiosarcoma After Surgical Resection: A Retrospective Study.
Lee BL, Chen CF, Chen PC, Lee HC, Liao WC, Perng CK, Ma H, Lin CH
Ann Plast Surg 2017 Mar;78(3 Suppl 2):S41-S46. doi: 10.1097/SAP.0000000000001004. PMID: 28118230
Neoadjuvant chemotherapy for primary cutaneous/soft tissue angiosarcoma: Determining tumor behavior prior to surgical resection.
Oxenberg J, Khushalani NI, Salerno KE, Attwood K, Kane JM 3rd
J Surg Oncol 2015 Jun;111(7):829-33. Epub 2015 Mar 13 doi: 10.1002/jso.23891. PMID: 25772798
Angiosarcoma of skin and soft tissue: a study of forty-four cases.
Maddox JC, Evans HL
Cancer 1981 Oct 15;48(8):1907-21. doi: 10.1002/1097-0142(19811015)48:8<1907::aid-cncr2820480832>3.0.co;2-t. PMID: 7197190

Clinical prediction guides

Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma.
Mao J, Hu J, Chen Y, Li Y, Run X
J Dermatolog Treat 2022 Aug;33(5):2466-2474. Epub 2021 Aug 24 doi: 10.1080/09546634.2021.1968333. PMID: 34429003
Investigation of Prognostic Features in Primary Cutaneous and Soft Tissue Angiosarcoma After Surgical Resection: A Retrospective Study.
Lee BL, Chen CF, Chen PC, Lee HC, Liao WC, Perng CK, Ma H, Lin CH
Ann Plast Surg 2017 Mar;78(3 Suppl 2):S41-S46. doi: 10.1097/SAP.0000000000001004. PMID: 28118230

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