U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis, Not Otherwise Specified

MedGen UID:
414880
Concept ID:
C2826330
Neoplastic Process
Synonyms: Essential Thrombocythemia with Ring Sideroblasts; MDS/MPN with Ring Sideroblasts and Thrombocytosis; Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis; Myelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis, NOS; Refractory Anemia with Ring Sideroblasts Associated with Marked Thrombocytosis

Definition

A myelodysplastic/myeloproliferative neoplasm characterized by marked thrombocytosis, anemia, erythroid lineage dysplasia, presence or absence of multilineage dysplasia, 15% or more ring sideroblasts, blasts less than 5% in bone marrow and less than 1% in peripheral blood, absence of BCR/ABL fusion, absence of SF3B1 mutation, absence of genetic abnormalities associated with myeloid/lymphoid neoplasms with eosinophilia and tyrosine kinase gene fusions, and no history of other myelodysplastic/myeloproliferative neoplasms or myeloproliferative neoplasms and myelodysplastic syndromes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyelodysplastic/Myeloproliferative Neoplasm with Ring Sideroblasts and Thrombocytosis, Not Otherwise Specified

Professional guidelines

PubMed

Tefferi A, Vannucchi AM, Barbui T
Am J Hematol 2024 Apr;99(4):697-718. Epub 2024 Jan 25 doi: 10.1002/ajh.27216. PMID: 38269572
Patnaik MM, Tefferi A
Am J Hematol 2021 Mar 1;96(3):379-394. Epub 2021 Jan 28 doi: 10.1002/ajh.26090. PMID: 33428785
Patnaik MM, Tefferi A
Am J Hematol 2019 Apr;94(4):475-488. Epub 2019 Jan 24 doi: 10.1002/ajh.25397. PMID: 30618061Free PMC Article

Recent clinical studies

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...