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Type A Lymphomatoid Papulosis

MedGen UID:: 234447
•Concept ID:: C1336841
•: Neoplastic Process

Synonym:

Type A LyP

Definition

A variant of lymphomatoid papulosis characterized by the presence of scattered anaplastic large lymphocytes, often resembling Reed-Sternberg cells, admixed with acute and chronic inflammatory cells. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVType A Lymphomatoid Papulosis

Hematopoietic and Lymphoid System Disorder
- Hematologic disorder
  - Hematopoietic and lymphoid cell neoplasm
    - Cutaneous Hematopoietic and Lymphoid Cell Neoplasm
      - Cutaneous Mature T-Cell and NK-Cell Neoplasm
        Lymphomatoid papulosis
        Type A Lymphomatoid Papulosis

Professional guidelines

PubMed

Brentuximab vedotin therapy for CD30-positive cutaneous T-cell lymphoma: a targeted approach to management.

Scarisbrick JJ
Future Oncol 2017 Nov;13(27):2405-2411. Epub 2017 Aug 14 doi: 10.2217/fon-2017-0263. PMID: 28805086

Histopathological aspects and differential diagnosis of CD8 positive lymphomatoid papulosis.

Marschalkó M, Gyöngyösi N, Noll J, Károlyi Z, Wikonkál N, Hársing J, Kuroli E, Csomor J, Matolcsy A, Sarolta K, Szepesi Á
J Cutan Pathol 2016 Nov;43(11):963-973. Epub 2016 Aug 30 doi: 10.1111/cup.12779. PMID: 27461449

Recent clinical studies

Etiology

Type A lymphomatoid papulosis presenting as an eyelid ulcer in a young man.

Sánchez España JC, Secondi R
Orbit 2019 Dec;38(6):495-499. Epub 2019 Jan 15 doi: 10.1080/01676830.2018.1563198. PMID: 30644803

Diagnosis

Type A lymphomatoid papulosis presenting as an eyelid ulcer in a young man.

Sánchez España JC, Secondi R
Orbit 2019 Dec;38(6):495-499. Epub 2019 Jan 15 doi: 10.1080/01676830.2018.1563198. PMID: 30644803

CD30 Positive Lymphomatoid Angiocentric Drug Reactions: Characterization of a Series of 20 Cases.

Magro CM, Olson LC, Nguyen GH, de Feraudy SM
Am J Dermatopathol 2017 Jul;39(7):508-517. doi: 10.1097/DAD.0000000000000692. PMID: 27655118

Therapy

Type A lymphomatoid papulosis presenting as an eyelid ulcer in a young man.

Sánchez España JC, Secondi R
Orbit 2019 Dec;38(6):495-499. Epub 2019 Jan 15 doi: 10.1080/01676830.2018.1563198. PMID: 30644803

Lymphomatoid papulosis and Hodgkin's disease: report of a case.

Koeppel MC, Horschowski N, Terrier G, Andrac L, Stoppa AM, Signoret R, Sayag J
Dermatology 1994;189(2):188-92. doi: 10.1159/000246830. PMID: 7521232

Clinical prediction guides

CD30 Positive Lymphomatoid Angiocentric Drug Reactions: Characterization of a Series of 20 Cases.

Magro CM, Olson LC, Nguyen GH, de Feraudy SM
Am J Dermatopathol 2017 Jul;39(7):508-517. doi: 10.1097/DAD.0000000000000692. PMID: 27655118

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