U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Parotid gland adenoid cystic carcinoma

MedGen UID:
277502
•Concept ID:
C1335355
•
Neoplastic Process
Synonyms: Adenoid Cystic Carcinoma of Parotid; adenoid cystic carcinoma of parotid; Adenoid cystic carcinoma of parotid gland; Adenoid Cystic Carcinoma of Parotid Gland; adenoid cystic carcinoma of parotid gland; Adenoid Cystic Carcinoma of the Parotid; adenoid cystic carcinoma of the parotid; Adenoid Cystic Carcinoma of the Parotid Gland; adenoid cystic carcinoma of the parotid gland; Parotid Adenoid Cystic Carcinoma; parotid adenoid cystic carcinoma; Parotid Gland Adenoid Cystic Carcinoma; parotid gland adenoid cystic carcinoma
SNOMED CT: Adenoid cystic carcinoma of parotid gland (423615009)
 
Monarch Initiative: MONDO:0006356

Definition

An aggressive carcinoma that arises from the parotid gland. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVParotid gland adenoid cystic carcinoma

Professional guidelines

PubMed

Submandibular gland cancer: Specific features and treatment considerations.
Aro K, Tarkkanen J, Saat R, Saarilahti K, Mäkitie A, Atula T
Head Neck 2018 Jan;40(1):154-162. Epub 2017 Oct 30 doi: 10.1002/hed.24981. PMID: 29083518
Diagnosis and Management of Malignant Salivary Gland Tumors of the Parotid Gland.
Lewis AG, Tong T, Maghami E
Otolaryngol Clin North Am 2016 Apr;49(2):343-80. doi: 10.1016/j.otc.2015.11.001. PMID: 27040585
Management of salivary gland tumors.
Andry G, Hamoir M, Locati LD, Licitra L, Langendijk JA
Expert Rev Anticancer Ther 2012 Sep;12(9):1161-8. doi: 10.1586/era.12.92. PMID: 23098116

Recent clinical studies

Etiology

Adenoid cystic carcinoma of parotid gland treated with surgery and radiotherapy: long-term outcomes, QoL assessment and review of the literature.
Al-Mamgani A, van Rooij P, Sewnaik A, Tans L, Hardillo JA
Oral Oncol 2012 Mar;48(3):278-83. Epub 2011 Nov 16 doi: 10.1016/j.oraloncology.2011.10.014. PMID: 22093375

Diagnosis

Garcin syndrome caused by parotid gland adenoid cystic carcinoma: A case report.
Xia NG, Chen YY, Wang XS, Xu HQ, Zheng RY
Medicine (Baltimore) 2017 Nov;96(45):e8508. doi: 10.1097/MD.0000000000008508. PMID: 29137049Free PMC Article
First bite syndrome as presenting symptom of parapharyngeal adenoid cystic carcinoma.
Deganello A, Meccariello G, Busoni M, Franchi A, Gallo O
J Laryngol Otol 2011 Apr;125(4):428-31. Epub 2011 Jan 27 doi: 10.1017/S002221511000294X. PMID: 21272418
Adenoid cystic carcinoma of the submandibular gland with symptomatic ovarian metastases.
Longacre TA, O'Hanlan K, Hendrickson MR
Int J Gynecol Pathol 1996 Oct;15(4):349-55. doi: 10.1097/00004347-199610000-00008. PMID: 8886883

Therapy

Iris metastasis from adenoid cystic carcinoma of parotid gland.
Montero J, Shields CL, Bianciotto C, Shields JA, Ehya H
Cornea 2011 Mar;30(3):351-3. doi: 10.1097/ICO.0b013e3181e9af33. PMID: 21045673

Prognosis

Adenoid cystic carcinoma of parotid gland treated with surgery and radiotherapy: long-term outcomes, QoL assessment and review of the literature.
Al-Mamgani A, van Rooij P, Sewnaik A, Tans L, Hardillo JA
Oral Oncol 2012 Mar;48(3):278-83. Epub 2011 Nov 16 doi: 10.1016/j.oraloncology.2011.10.014. PMID: 22093375
Iris metastasis from adenoid cystic carcinoma of parotid gland.
Montero J, Shields CL, Bianciotto C, Shields JA, Ehya H
Cornea 2011 Mar;30(3):351-3. doi: 10.1097/ICO.0b013e3181e9af33. PMID: 21045673

Clinical prediction guides

Adenoid cystic carcinoma of parotid gland treated with surgery and radiotherapy: long-term outcomes, QoL assessment and review of the literature.
Al-Mamgani A, van Rooij P, Sewnaik A, Tans L, Hardillo JA
Oral Oncol 2012 Mar;48(3):278-83. Epub 2011 Nov 16 doi: 10.1016/j.oraloncology.2011.10.014. PMID: 22093375

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...