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Cervical mucinous adenocarcinoma

MedGen UID:
232048
•Concept ID:
C1332919
•
Neoplastic Process
Synonyms: Cervical Mucinous Adenocarcinoma; cervical mucinous adenocarcinoma; uterine cervix mucinous adenocarcinoma
 
Monarch Initiative: MONDO:0002742

Definition

A mucinous adenocarcinoma arising from the endocervical glandular epithelium. It is characterized by the presence of malignant glandular cells that contain significant amount of intracytoplasmic mucin. Histologic variants include intestinal-type, signet ring-type, gastric-type, cervical invasive stratified mucinous adenocarcinoma, and mucinous adenocarcinoma, not otherwise specified. All histologic variants except gastric-type adenocarcinoma are associated with human papillomavirus infection. [from NCI]

Professional guidelines

PubMed

Impact of Histopathological Risk Factors on the Treatment of Stage IB-IIB Uterine Cervical Cancer.
Shimada M, Tokunaga H, Kigawa J, Yaegashi N
Tohoku J Exp Med 2020 Dec;252(4):339-351. doi: 10.1620/tjem.252.339. PMID: 33311005
International Endocervical Adenocarcinoma Criteria and Classification: Validation and Interobserver Reproducibility.
Hodgson A, Park KJ, Djordjevic B, Howitt BE, Nucci MR, Oliva E, Stolnicu S, Xu B, Soslow RA, Parra-Herran C
Am J Surg Pathol 2019 Jan;43(1):75-83. doi: 10.1097/PAS.0000000000001095. PMID: 29877920Free PMC Article
International Endocervical Adenocarcinoma Criteria and Classification (IECC): A New Pathogenetic Classification for Invasive Adenocarcinomas of the Endocervix.
Stolnicu S, Barsan I, Hoang L, Patel P, Terinte C, Pesci A, Aviel-Ronen S, Kiyokawa T, Alvarado-Cabrero I, Pike MC, Oliva E, Park KJ, Soslow RA
Am J Surg Pathol 2018 Feb;42(2):214-226. doi: 10.1097/PAS.0000000000000986. PMID: 29135516Free PMC Article

Recent clinical studies

Etiology

Analysis of prognostic factors for cervical mucinous adenocarcinoma and establishment and validation a nomogram: a SEER-based study.
Hao Y, Liu Q, Li R, Mao Z, Jiang N, Wang B, Zhang W, Cui B
J Obstet Gynaecol 2023 Dec;43(1):2153027. Epub 2022 Dec 8 doi: 10.1080/01443615.2022.2153027. PMID: 36480157

Diagnosis

Analysis of prognostic factors for cervical mucinous adenocarcinoma and establishment and validation a nomogram: a SEER-based study.
Hao Y, Liu Q, Li R, Mao Z, Jiang N, Wang B, Zhang W, Cui B
J Obstet Gynaecol 2023 Dec;43(1):2153027. Epub 2022 Dec 8 doi: 10.1080/01443615.2022.2153027. PMID: 36480157

Prognosis

Analysis of prognostic factors for cervical mucinous adenocarcinoma and establishment and validation a nomogram: a SEER-based study.
Hao Y, Liu Q, Li R, Mao Z, Jiang N, Wang B, Zhang W, Cui B
J Obstet Gynaecol 2023 Dec;43(1):2153027. Epub 2022 Dec 8 doi: 10.1080/01443615.2022.2153027. PMID: 36480157

Clinical prediction guides

Analysis of prognostic factors for cervical mucinous adenocarcinoma and establishment and validation a nomogram: a SEER-based study.
Hao Y, Liu Q, Li R, Mao Z, Jiang N, Wang B, Zhang W, Cui B
J Obstet Gynaecol 2023 Dec;43(1):2153027. Epub 2022 Dec 8 doi: 10.1080/01443615.2022.2153027. PMID: 36480157

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