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Appendix cancer

MedGen UID:
141676
Concept ID:
C0496779
Neoplastic Process
Synonyms: Appendiceal Cancer; Appendix Cancer; Cancer of Appendix; Cancer of the Appendix; Cancer, Appendiceal; Cancer, Appendix
SNOMED CT: Malignant tumor of appendix (363411007); Appendiceal cancer (363411007); Malignant neoplasm of appendix (363411007)
 
Monarch Initiative: MONDO:0001235

Definition

A primary or metastatic malignant neoplasm that affects the appendix. Representative examples include carcinoma and lymphoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAppendix cancer

Professional guidelines

PubMed

Graves A, Sadjadi J, Kosich M, Ward E, Sood D, Fahy B, Pankratz S, Mishra SI, Greenbaum A
Ann Surg Oncol 2024 Nov;31(12):7978-7986. Epub 2024 Aug 27 doi: 10.1245/s10434-024-16013-1. PMID: 39192009
Kubeček O, Laco J, Špaček J, Petera J, Kopecký J, Kubečková A, Filip S
Clin Exp Metastasis 2017 Jun;34(5):295-307. Epub 2017 Jul 20 doi: 10.1007/s10585-017-9856-8. PMID: 28730323Free PMC Article

Recent clinical studies

Etiology

Yousef A, Yousef M, Zeineddine MA, More A, Fanaeian M, Chowdhury S, Knafl M, Edelkamp P, Ito I, Gu Y, Pattalachinti V, Naini ZA, Zeineddine FA, Peterson J, Alfaro K, Foo WC, Jin J, Bhutiani N, Higbie V, Scally CP, Kee B, Kopetz S, Goldstein D, Strach M, Williamson A, Aziz O, Barriuso J, Uppal A, White MG, Helmink B, Fournier KF, Raghav KP, Taggart MW, Overman MJ, Shen JP
JAMA Netw Open 2024 Feb 5;7(2):e240260. doi: 10.1001/jamanetworkopen.2024.0260. PMID: 38416491Free PMC Article
Dhiman A, Kothary V, Witmer HDD, Bregio C, Sood D, Ong CT, Polite B, Eng OS, Shergill A, Turaga KK
Ann Surg 2023 Dec 1;278(6):925-931. Epub 2023 Mar 30 doi: 10.1097/SLA.0000000000005856. PMID: 36994703
Eftimie MA, Potlog G, Alexandrescu ST
Medicina (Kaunas) 2023 Jan 28;59(2) doi: 10.3390/medicina59020255. PMID: 36837456Free PMC Article
Kubeček O, Laco J, Špaček J, Petera J, Kopecký J, Kubečková A, Filip S
Clin Exp Metastasis 2017 Jun;34(5):295-307. Epub 2017 Jul 20 doi: 10.1007/s10585-017-9856-8. PMID: 28730323Free PMC Article
Pinto A, Eveno C, Pocard M
Int J Hyperthermia 2017 Aug;33(5):543-547. doi: 10.1080/02656736.2017.1289565. PMID: 28142288

Diagnosis

Yousef A, Yousef M, Zeineddine MA, More A, Fanaeian M, Chowdhury S, Knafl M, Edelkamp P, Ito I, Gu Y, Pattalachinti V, Naini ZA, Zeineddine FA, Peterson J, Alfaro K, Foo WC, Jin J, Bhutiani N, Higbie V, Scally CP, Kee B, Kopetz S, Goldstein D, Strach M, Williamson A, Aziz O, Barriuso J, Uppal A, White MG, Helmink B, Fournier KF, Raghav KP, Taggart MW, Overman MJ, Shen JP
JAMA Netw Open 2024 Feb 5;7(2):e240260. doi: 10.1001/jamanetworkopen.2024.0260. PMID: 38416491Free PMC Article
Dhiman A, Kothary V, Witmer HDD, Bregio C, Sood D, Ong CT, Polite B, Eng OS, Shergill A, Turaga KK
Ann Surg 2023 Dec 1;278(6):925-931. Epub 2023 Mar 30 doi: 10.1097/SLA.0000000000005856. PMID: 36994703
Yilmaz S, Bolukbasi H
Indian J Cancer 2023 Jul-Sep;60(3):331-336. doi: 10.4103/ijc.IJC_1121_20. PMID: 36861689
Kubeček O, Laco J, Špaček J, Petera J, Kopecký J, Kubečková A, Filip S
Clin Exp Metastasis 2017 Jun;34(5):295-307. Epub 2017 Jul 20 doi: 10.1007/s10585-017-9856-8. PMID: 28730323Free PMC Article
Gehrig PA, Boggess JF, Ollila DW, Groben PA, Van Le L
Int J Gynecol Cancer 2002 Nov-Dec;12(6):768-72. doi: 10.1046/j.1525-1438.2002.01136.x. PMID: 12445258

Therapy

Morgan RB, Dhiman A, Kim AC, Shergill A, Polite B, Turaga KK, Eng OS
J Gastrointest Surg 2023 Nov;27(11):2560-2562. Epub 2023 Jun 12 doi: 10.1007/s11605-023-05747-0. PMID: 37308734
Dhiman A, Kothary V, Witmer HDD, Bregio C, Sood D, Ong CT, Polite B, Eng OS, Shergill A, Turaga KK
Ann Surg 2023 Dec 1;278(6):925-931. Epub 2023 Mar 30 doi: 10.1097/SLA.0000000000005856. PMID: 36994703
Eftimie MA, Potlog G, Alexandrescu ST
Medicina (Kaunas) 2023 Jan 28;59(2) doi: 10.3390/medicina59020255. PMID: 36837456Free PMC Article
Yuksel C, Basceken SI, Ersen O, Culcu S, Mercan U, Bakırarar B, Unal AE
Ann Ital Chir 2022;93:584-591. PMID: 36254768
Dilly AK, Honick BD, Frederick R, Elapavaluru A, Velankar S, Makala H, Hitchens TK, Foley LM, Guo J, Beumer JH, Rigatti LH, Lee YJ, Bartlett DL, Choudry HA
Transl Res 2021 Mar;229:100-114. Epub 2020 Oct 22 doi: 10.1016/j.trsl.2020.10.005. PMID: 33164812Free PMC Article

Prognosis

Janczewski LM, Browner AE, Cotler JH, Nelson H, Kakar S, Carr NJ, Hanna NN, Holowatyj AN, Goldberg RM, Washington MK, Asare EA, Overman MJ; American Joint Committee on Cancer Expert Panel on Cancers for the Lower Gastrointestinal Appendix Disease Site
CA Cancer J Clin 2023 Nov-Dec;73(6):590-596. Epub 2023 Jun 26 doi: 10.3322/caac.21806. PMID: 37358310
Dhiman A, Kothary V, Witmer HDD, Bregio C, Sood D, Ong CT, Polite B, Eng OS, Shergill A, Turaga KK
Ann Surg 2023 Dec 1;278(6):925-931. Epub 2023 Mar 30 doi: 10.1097/SLA.0000000000005856. PMID: 36994703
Eftimie MA, Potlog G, Alexandrescu ST
Medicina (Kaunas) 2023 Jan 28;59(2) doi: 10.3390/medicina59020255. PMID: 36837456Free PMC Article
Yuksel C, Basceken SI, Ersen O, Culcu S, Mercan U, Bakırarar B, Unal AE
Ann Ital Chir 2022;93:584-591. PMID: 36254768
Sommariva A, Tonello M, De Simoni O, Barina A, Riccardo Rossi C, Pilati P
Asian J Endosc Surg 2020 Oct;13(4):614-617. Epub 2020 Jan 29 doi: 10.1111/ases.12784. PMID: 31997552

Clinical prediction guides

Strach MC, Chakrabarty B, Nagaraju RT, Mullamitha S, Braun M, O'Dwyer ST, Aziz O, Barriuso J
ESMO Open 2023 Oct;8(5):101619. Epub 2023 Aug 24 doi: 10.1016/j.esmoop.2023.101619. PMID: 37625193Free PMC Article
Dhiman A, Kothary V, Witmer HDD, Bregio C, Sood D, Ong CT, Polite B, Eng OS, Shergill A, Turaga KK
Ann Surg 2023 Dec 1;278(6):925-931. Epub 2023 Mar 30 doi: 10.1097/SLA.0000000000005856. PMID: 36994703
Yuksel C, Basceken SI, Ersen O, Culcu S, Mercan U, Bakırarar B, Unal AE
Ann Ital Chir 2022;93:584-591. PMID: 36254768
Shamavonian R, Lansom JD, Karpes JB, Alzahrani NA, Morris DL
Eur J Surg Oncol 2021 Jan;47(1):194-198. Epub 2020 Nov 28 doi: 10.1016/j.ejso.2020.11.134. PMID: 33272738
Shannon AB, Goldberg D, Song Y, Paulson EC, Roses RE, Fraker DL, Kelz RR, Miura J, Karakousis GC
J Surg Oncol 2020 Sep;122(3):399-406. Epub 2020 Apr 28 doi: 10.1002/jso.25963. PMID: 32346885

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