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Tubular adenoma

MedGen UID:: 83123
•Concept ID:: C0334292
•: Neoplastic Process

Synonyms:	adenoma, tubular cell, benign; Gastrointestinal Tract Tubular Adenoma; GI Tract Tubular Adenoma; Tubular Adenoma; tubular adenoma
SNOMED CT:	Tubular adenoma (444408007)

Monarch Initiative:	MONDO:0024660

Definition

An adenoma arising from the glandular epithelium of the gastrointestinal tract. It is characterized by the presence of a tubular architectural pattern. Most often it occurs in the large intestine, small intestine, and the stomach. The neoplastic epithelial cells show dysplastic features. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVTubular adenoma

Pathological process
- Disease
  - Neoplasm
    - Epithelial neoplasm
      - Adenoma
        Digestive system adenoma
        Tubular adenoma
        Ampulla of Vater Tubular Adenoma
        Appendix Tubular Adenoma
        Colorectal Tubular Adenoma
        Colon Tubular Adenoma
        Rectal tubular adenoma
        Extrahepatic Bile Duct Tubular Adenoma
        Gastric Tubular Adenoma
        Small intestinal tubular adenoma

Professional guidelines

PubMed

Diagnostic yield of repeat screening colonoscopy ten years after an adenoma-negative index screening endoscopy.

V Schönfeld P, Hauser D, Baldus SE, Özer EY, V Schönfeld J
Z Gastroenterol 2023 Feb;61(2):151-154. Epub 2022 May 9 doi: 10.1055/a-1800-9928. PMID: 35533687

Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.

Kurian AW, Hare EE, Mills MA, Kingham KE, McPherson L, Whittemore AS, McGuire V, Ladabaum U, Kobayashi Y, Lincoln SE, Cargill M, Ford JM
J Clin Oncol 2014 Jul 1;32(19):2001-9. Epub 2014 Apr 14 doi: 10.1200/JCO.2013.53.6607. PMID: 24733792 Free PMC Article

Polyp guideline: diagnosis, treatment, and surveillance for patients with nonfamilial colorectal polyps. The Practice Parameters Committee of the American College of Gastroenterology.

Bond JH
Ann Intern Med 1993 Oct 15;119(8):836-43. doi: 10.7326/0003-4819-119-8-199310150-00010. PMID: 8379605

See all (10)

Recent clinical studies

Etiology

Tubular Adenoma of the Breast: Radiologic-Pathologic Correlation.

Joo GJ, Carter GJ, Berg WA
J Breast Imaging 2023 Nov 30;5(6):703-711. doi: 10.1093/jbi/wbad066. PMID: 38141235

Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey.

Kervarrec T, Tallet A, Macagno N, de la Fouchardière A, Pissaloux D, Tirode F, Bravo IG, Nicolas A, Baulande S, Sohier P, Balme B, Osio A, Jullie ML, Moulonguet I, Bonsang B, Tournier E, Herfs M, Frouin E, Zidan A, Calonje E, Berthon P, Touzé A, Seris A, Mortier L, Jouary T, Cribier B, Battistella M
Am J Surg Pathol 2023 Oct 1;47(10):1096-1107. Epub 2023 Jul 31 doi: 10.1097/PAS.0000000000002098. PMID: 37505808

Microbiota and gastrointestinal cancer.

Weng MT, Chiu YT, Wei PY, Chiang CW, Fang HL, Wei SC
J Formos Med Assoc 2019 Mar;118 Suppl 1:S32-S41. Epub 2019 Jan 14 doi: 10.1016/j.jfma.2019.01.002. PMID: 30655033

Intraductal tubular neoplasms of the pancreas: an overview.

Chelliah A, Kalimuthu S, Chetty R
Ann Diagn Pathol 2016 Oct;24:68-72. Epub 2016 Apr 26 doi: 10.1016/j.anndiagpath.2016.04.009. PMID: 27185640

Colonic polyps.

Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

See all (231)

Diagnosis

Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey.

Synchronous occurrence of different polyp types during colonoscopy.

Sonnenberg A, Genta RM
Aliment Pharmacol Ther 2022 Sep;56(5):777-782. Epub 2022 Jun 23 doi: 10.1111/apt.17075. PMID: 35735899

Trends of Colonic Neoplasia in US Outpatient Endoscopy Centers.

Sonnenberg A, Turner KO, Genta RM
Dig Dis Sci 2022 Oct;67(10):4702-4707. Epub 2022 Jan 20 doi: 10.1007/s10620-021-07358-8. PMID: 35048223

Intraductal tubular neoplasms of the pancreas: an overview.

Chelliah A, Kalimuthu S, Chetty R
Ann Diagn Pathol 2016 Oct;24:68-72. Epub 2016 Apr 26 doi: 10.1016/j.anndiagpath.2016.04.009. PMID: 27185640

Colonic polyps.

Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

See all (283)

Therapy

Risk Factors Associated with Advanced Colorectal Neoplasia in Adults Younger than Age 45.

Bolwell J, Butler R, Burke CA, Liska D, Macaron C
J Clin Gastroenterol 2024 Oct 1;58(9):882-888. doi: 10.1097/MCG.0000000000001967. PMID: 38227841

BCDnet: Parallel heterogeneous eight-class classification model of breast pathology.

He Q, Cheng G, Ju H
PLoS One 2021;16(7):e0253764. Epub 2021 Jul 12 doi: 10.1371/journal.pone.0253764. PMID: 34252112 Free PMC Article

Relationship between serum gamma-glutamyl transferase level and colorectal adenoma.

Hong TC, Yang HC, Chen CL, Kao JH, Liu CJ, Chen MJ, Wang HY, Kuo YC, Yu LY, Hu KC
PLoS One 2020;15(10):e0240445. Epub 2020 Oct 13 doi: 10.1371/journal.pone.0240445. PMID: 33048943 Free PMC Article

Microbiota and gastrointestinal cancer.

Weng MT, Chiu YT, Wei PY, Chiang CW, Fang HL, Wei SC
J Formos Med Assoc 2019 Mar;118 Suppl 1:S32-S41. Epub 2019 Jan 14 doi: 10.1016/j.jfma.2019.01.002. PMID: 30655033

Cronkhite-Canada syndrome: report of six cases and review of literature.

Wen XH, Wang L, Wang YX, Qian JM
World J Gastroenterol 2014 Jun 21;20(23):7518-22. doi: 10.3748/wjg.v20.i23.7518. PMID: 24966624 Free PMC Article

See all (50)

Prognosis

Tubular Adenoma of the Breast: Radiologic-Pathologic Correlation.

Joo GJ, Carter GJ, Berg WA
J Breast Imaging 2023 Nov 30;5(6):703-711. doi: 10.1093/jbi/wbad066. PMID: 38141235

Pancreatobiliary maljunction: association with gallbladder cancer.

Garzón Benavides M, Núñez Ortiz A, López Ruiz T, Cepeda Franco C, Gómez Izquierdo L
Rev Esp Enferm Dig 2019 Jul;111(7):568-570. doi: 10.17235/reed.2019.6127/2018. PMID: 31215211

What are the Endoscopic and Pathological Characteristics of Colorectal Polyps?

Bas B, Dinc B, Oymaci E, Mayir B, Gunduz UR
Asian Pac J Cancer Prev 2015;16(13):5163-7. doi: 10.7314/apjcp.2015.16.13.5163. PMID: 26225647

If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.

Ma KW, Chia NH, Yeung HW, Cheung MT
Hong Kong Med J 2010 Feb;16(1):12-7. PMID: 20124568

Colonic polyps.

Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

See all (137)

Clinical prediction guides

Sweat Gland Tumors Arising on Acral Sites: A Molecular Survey.

Loss of alcohol dehydrogenase 1B in cancer-associated fibroblasts: contribution to the increase of tumor-promoting IL-6 in colon cancer.

Villéger R, Chulkina M, Mifflin RC, Markov NS, Trieu J, Sinha M, Johnson P, Saada JI, Adegboyega PA, Luxon BA, Beswick EJ, Powell DW, Pinchuk IV
Br J Cancer 2023 Feb;128(4):537-548. Epub 2022 Dec 8 doi: 10.1038/s41416-022-02066-0. PMID: 36482184 Free PMC Article

Cronkhite-Canada syndrome: An investigation in clinical features and pathogenesis.

Zhu LP, Zhong WL, Wang ZG, Sun KD, Liu QLF, Zhao J, Zhao JW, Chen X, Wang BM
J Dig Dis 2021 Nov;22(11):663-671. doi: 10.1111/1751-2980.13062. PMID: 34697888

Analysis of clinical and histopathological findings in Russell body gastritis and duodenitis.

Altindag SD, Cakir E, Ekinci N, Avci A, Dilek FH
Ann Diagn Pathol 2019 Jun;40:66-71. Epub 2019 Apr 3 doi: 10.1016/j.anndiagpath.2019.04.003. PMID: 31031217

Microbiota and gastrointestinal cancer.

Weng MT, Chiu YT, Wei PY, Chiang CW, Fang HL, Wei SC
J Formos Med Assoc 2019 Mar;118 Suppl 1:S32-S41. Epub 2019 Jan 14 doi: 10.1016/j.jfma.2019.01.002. PMID: 30655033

See all (154)

Recent systematic reviews

Site-specific risk of colorectal neoplasms in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis.

Lin X, You F, Liu H, Fang Y, Jin S, Wang Q
PLoS One 2021;16(1):e0245921. Epub 2021 Jan 25 doi: 10.1371/journal.pone.0245921. PMID: 33493235 Free PMC Article

See all (1)

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Tubular adenoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

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Practice guidelines

Consumer resources

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