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Appendix Tubular Adenoma

MedGen UID:
353392
•Concept ID:
C1706834
•
Neoplastic Process

Definition

An adenoma arising from the appendix. It is characterized by the presence of tubular epithelial structures and it is associated with dysplasia. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAppendix Tubular Adenoma

Recent clinical studies

Etiology

The role of advanced endoscopy in appendiceal polyp management and outcomes.
Justiniano CF, Ozgur I, Liska D, Valente MA, Steele SR, Gorgun E
Surg Endosc 2024 Apr;38(4):2267-2272. Epub 2024 Mar 4 doi: 10.1007/s00464-024-10726-w. PMID: 38438673Free PMC Article
Clinicopathological spectrums and prognosis of primary appendiceal adenocarcinoma, goblet cell adenocarcinoma, and low-grade appendiceal mucinous neoplasms.
Chen I, Liu X, Kovar-Peltz S, Conrad SJ, Chen HH, Liao X
Pathology 2023 Apr;55(3):375-382. Epub 2022 Oct 13 doi: 10.1016/j.pathol.2022.08.004. PMID: 36454563
Molecular profiling of appendiceal serrated lesions, polyps and mucinous neoplasms: a single-centre experience.
Munari G, Businello G, Mattiolo P, Pennelli G, Sbaraglia M, Borga C, Pucciarelli S, Spolverato G, Mescoli C, Galuppini F, Sommariva A, Bellan E, Lonardi S, Loupakis F, Luchini C, Dei Tos AP, Fassan M
J Cancer Res Clin Oncol 2021 Jul;147(7):1897-1904. Epub 2021 Mar 12 doi: 10.1007/s00432-021-03589-4. PMID: 33712927Free PMC Article
Underwater EMR of adenomas of the appendiceal orifice (with video).
Binmoeller KF, Hamerski CM, Shah JN, Bhat YM, Kane SD
Gastrointest Endosc 2016 Mar;83(3):638-42. Epub 2015 Sep 14 doi: 10.1016/j.gie.2015.08.079. PMID: 26375437
If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.
Ma KW, Chia NH, Yeung HW, Cheung MT
Hong Kong Med J 2010 Feb;16(1):12-7. PMID: 20124568

Diagnosis

Clinicopathological spectrums and prognosis of primary appendiceal adenocarcinoma, goblet cell adenocarcinoma, and low-grade appendiceal mucinous neoplasms.
Chen I, Liu X, Kovar-Peltz S, Conrad SJ, Chen HH, Liao X
Pathology 2023 Apr;55(3):375-382. Epub 2022 Oct 13 doi: 10.1016/j.pathol.2022.08.004. PMID: 36454563
Simultaneous giant mucinous cystadenoma of the appendix and intestinal schistosomiasis: 'case report and brief review'.
Lin C, Li X, Guo Y, Hu G, Zhang Y, Yang K, Gan Y, Zhou J, Lv L, Gao K, Du J
World J Surg Oncol 2014 Dec 17;12:385. doi: 10.1186/1477-7819-12-385. PMID: 25518977Free PMC Article
Achieving a complete colonic evaluation in patients with incomplete colonoscopy is worth the effort.
Ridolfi TJ, Valente MA, Church JM
Dis Colon Rectum 2014 Mar;57(3):383-7. doi: 10.1097/DCR.0000000000000072. PMID: 24509464
If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.
Ma KW, Chia NH, Yeung HW, Cheung MT
Hong Kong Med J 2010 Feb;16(1):12-7. PMID: 20124568
Unusual tumors of the appendix and pseudomyxoma peritonei.
Carr NJ, Sobin LH
Semin Diagn Pathol 1996 Nov;13(4):314-25. PMID: 8946609

Therapy

Outcome of laparoscopic colectomy for polyps not suitable for endoscopic resection.
Pokala N, Delaney CP, Kiran RP, Brady K, Senagore AJ
Surg Endosc 2007 Mar;21(3):400-3. Epub 2006 Dec 16 doi: 10.1007/s00464-006-9069-8. PMID: 17180271

Prognosis

Clinicopathological spectrums and prognosis of primary appendiceal adenocarcinoma, goblet cell adenocarcinoma, and low-grade appendiceal mucinous neoplasms.
Chen I, Liu X, Kovar-Peltz S, Conrad SJ, Chen HH, Liao X
Pathology 2023 Apr;55(3):375-382. Epub 2022 Oct 13 doi: 10.1016/j.pathol.2022.08.004. PMID: 36454563
Molecular profiling of appendiceal serrated lesions, polyps and mucinous neoplasms: a single-centre experience.
Munari G, Businello G, Mattiolo P, Pennelli G, Sbaraglia M, Borga C, Pucciarelli S, Spolverato G, Mescoli C, Galuppini F, Sommariva A, Bellan E, Lonardi S, Loupakis F, Luchini C, Dei Tos AP, Fassan M
J Cancer Res Clin Oncol 2021 Jul;147(7):1897-1904. Epub 2021 Mar 12 doi: 10.1007/s00432-021-03589-4. PMID: 33712927Free PMC Article
If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.
Ma KW, Chia NH, Yeung HW, Cheung MT
Hong Kong Med J 2010 Feb;16(1):12-7. PMID: 20124568
Unusual tumors of the appendix and pseudomyxoma peritonei.
Carr NJ, Sobin LH
Semin Diagn Pathol 1996 Nov;13(4):314-25. PMID: 8946609
Dual carcinoid/epithelial neoplasia of the appendix.
Carr NJ, Remotti H, Sobin LH
Histopathology 1995 Dec;27(6):557-62. doi: 10.1111/j.1365-2559.1995.tb00327.x. PMID: 8838336

Clinical prediction guides

The role of advanced endoscopy in appendiceal polyp management and outcomes.
Justiniano CF, Ozgur I, Liska D, Valente MA, Steele SR, Gorgun E
Surg Endosc 2024 Apr;38(4):2267-2272. Epub 2024 Mar 4 doi: 10.1007/s00464-024-10726-w. PMID: 38438673Free PMC Article
Appendiceal mucinous neoplasms: an uncertain nosological entity. Report of a case.
Agrusa A, Romano G, Galia M, Cucinella G, Sorce V, Di Buono G, Agnello F, Amato G, Gulotta G
G Chir 2016 Mar-Apr;37(2):86-9. doi: 10.11138/gchir/2016.37.2.086. PMID: 27381696Free PMC Article
Underwater EMR of adenomas of the appendiceal orifice (with video).
Binmoeller KF, Hamerski CM, Shah JN, Bhat YM, Kane SD
Gastrointest Endosc 2016 Mar;83(3):638-42. Epub 2015 Sep 14 doi: 10.1016/j.gie.2015.08.079. PMID: 26375437
If not appendicitis, then what else can it be? A retrospective review of 1492 appendectomies.
Ma KW, Chia NH, Yeung HW, Cheung MT
Hong Kong Med J 2010 Feb;16(1):12-7. PMID: 20124568

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