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Spindle cell sarcoma

MedGen UID:
64477
Concept ID:
C0205945
Neoplastic Process
Synonyms: Sarcoma, Spindle Cell; Sarcomas, Spindle Cell; Spindle Cell Sarcoma; Spindle Cell Sarcomas
SNOMED CT: Spindle cell sarcoma (9801004)
 
Monarch Initiative: MONDO:0002927

Definition

A malignant mesenchymal neoplasm composed of spindle-shaped cells. This is a morphologic term which can be applied to a wide range of sarcomas. [from NCI]

Professional guidelines

PubMed

Thway K, Fisher C
Semin Diagn Pathol 2021 Nov;38(6):170-186. Epub 2021 Sep 29 doi: 10.1053/j.semdp.2021.09.005. PMID: 34602314
Lee Y, Kim HJ, Yoon H, Choi CM, Oh YM, Lee SD, Lim CM, Kim WS, Koh Y, Lee JS
J Korean Med Sci 2016 Nov;31(11):1755-1760. doi: 10.3346/jkms.2016.31.11.1755. PMID: 27709853Free PMC Article
Goldstein JA, Cates JM
Adv Anat Pathol 2015 Jul;22(4):260-6. doi: 10.1097/PAP.0000000000000077. PMID: 26050263

Recent clinical studies

Etiology

Gambarotti M, Righi A, Sbaraglia M, Cocchi S, Benini S, Magagnoli G, Frisoni T, Palmerini E, Picci P, Dei Tos AP
Hum Pathol 2022 Apr;122:92-102. Epub 2022 Feb 15 doi: 10.1016/j.humpath.2022.02.003. PMID: 35176251
Musser E, Smolle M, Friesenbichler J, Leithner A, Bergovec M
Orthop Traumatol Surg Res 2019 Oct;105(6):1211-1213. Epub 2019 Jun 14 doi: 10.1016/j.otsr.2019.04.013. PMID: 31208933
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183
Kremer J, Farag M, Arif R, Brcic A, Sabashnikov A, Schmack B, Popov AF, Karck M, Dohmen PM, Ruhparwar A, Weymann A
Med Sci Monit Basic Res 2016 Nov 2;22:128-131. doi: 10.12659/msmbr.901526. PMID: 27803495Free PMC Article
Mitchell AD, Ayoub K, Mangham DC, Grimer RJ, Carter SR, Tillman RM
J Bone Joint Surg Br 2000 Jan;82(1):55-61. doi: 10.1302/0301-620x.82b1.9020. PMID: 10697315

Diagnosis

Hosmann A, Kamdar V, Misra BK
Acta Neurochir (Wien) 2024 Jan 30;166(1):52. doi: 10.1007/s00701-024-05921-6. PMID: 38289497
Chapman LW, Yu SS, Arron ST
Semin Cutan Med Surg 2019 Mar 1;38(1):E65-E66. doi: 10.12788/j.sder.2019.008. PMID: 31051027
Thway K
Semin Diagn Pathol 2019 Mar;36(2):112-121. Epub 2019 Feb 28 doi: 10.1053/j.semdp.2019.02.006. PMID: 30852045
Ortiz MV, Magnan H, Slotkin EK, Ambati SR, Chou AJ, Wexler LH, Meyers PA, Walsh MF, Heaton T, Girardi LN, Wolden SL, Price AP, Kennedy JA, Zehir A, Hameed M, Berger MF, Kentsis A, Shukla N
J Pediatr Hematol Oncol 2017 Nov;39(8):e443-e445. doi: 10.1097/MPH.0000000000000754. PMID: 28060130Free PMC Article
Pinto A, Howitt B
Arch Pathol Lab Med 2016 Mar;140(3):286-90. doi: 10.5858/arpa.2014-0523-RS. PMID: 26927725

Therapy

Hosmann A, Kamdar V, Misra BK
Acta Neurochir (Wien) 2024 Jan 30;166(1):52. doi: 10.1007/s00701-024-05921-6. PMID: 38289497
Hrudka J, Charvát M, Grossmann P, Kinkor Z
Cesk Patol 2020 Spring;56(2):89-93. PMID: 32493025
Fomin VV, Kogan EA, Chichkova NV, Komarov RN, Fominykh EV, Shchedrina IS, Morosova NS, Karseladze AI
Ter Arkh 2018 Aug 27;90(8):69-73. doi: 10.26442/terarkh201890869-73. PMID: 30701941
Prevost JB, Bossi A, Sciot R, Debiec-Rychter M
Tumori 2004 Nov-Dec;90(6):618-21. doi: 10.1177/030089160409000615. PMID: 15762367
Ritchey ML, Bagnall JW, McDonald EC, Sago AL
J Urol 1985 Jul;134(1):146-9. doi: 10.1016/s0022-5347(17)47034-0. PMID: 4040179

Prognosis

Fukui S, Kobayashi K, Fujita Y, Fukui S, Iwamoto N, Adachi T, Hidaka M, Takatsuki M, Abe K, Kuwana M, Kawakami A, Eguchi S
Intern Med 2020 Aug 15;59(16):2071-2076. Epub 2020 May 23 doi: 10.2169/internalmedicine.3923-19. PMID: 32448829Free PMC Article
Fomin VV, Kogan EA, Chichkova NV, Komarov RN, Fominykh EV, Shchedrina IS, Morosova NS, Karseladze AI
Ter Arkh 2018 Aug 27;90(8):69-73. doi: 10.26442/terarkh201890869-73. PMID: 30701941
Pinto A, Howitt B
Arch Pathol Lab Med 2016 Mar;140(3):286-90. doi: 10.5858/arpa.2014-0523-RS. PMID: 26927725
Bossi M, Paolino LA, Valenti A, Marciano L, Polliand C, Ziol M, Barrat C
Rom J Morphol Embryol 2012;53(3):625-8. PMID: 22990557
Mitchell AD, Ayoub K, Mangham DC, Grimer RJ, Carter SR, Tillman RM
J Bone Joint Surg Br 2000 Jan;82(1):55-61. doi: 10.1302/0301-620x.82b1.9020. PMID: 10697315

Clinical prediction guides

Fukui S, Kobayashi K, Fujita Y, Fukui S, Iwamoto N, Adachi T, Hidaka M, Takatsuki M, Abe K, Kuwana M, Kawakami A, Eguchi S
Intern Med 2020 Aug 15;59(16):2071-2076. Epub 2020 May 23 doi: 10.2169/internalmedicine.3923-19. PMID: 32448829Free PMC Article
Musser E, Smolle M, Friesenbichler J, Leithner A, Bergovec M
Orthop Traumatol Surg Res 2019 Oct;105(6):1211-1213. Epub 2019 Jun 14 doi: 10.1016/j.otsr.2019.04.013. PMID: 31208933
Watson S, Perrin V, Guillemot D, Reynaud S, Coindre JM, Karanian M, Guinebretière JM, Freneaux P, Le Loarer F, Bouvet M, Galmiche-Rolland L, Larousserie F, Longchampt E, Ranchere-Vince D, Pierron G, Delattre O, Tirode F
J Pathol 2018 May;245(1):29-40. Epub 2018 Mar 30 doi: 10.1002/path.5053. PMID: 29431183
Gaston KE, White RL Jr, Homsi S, Teigland C
Am Surg 2007 Apr;73(4):377-80. doi: 10.1177/000313480707300413. PMID: 17439032
Tanimoto H, Shigemasa K, Sasaki M, Katayama H, Kusumi I, Parmley TH, O'Brien TJ, Ohama K
Oncol Rep 2000 Nov-Dec;7(6):1209-12. doi: 10.3892/or.7.6.1209. PMID: 11032915

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