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Contact dermatitis

MedGen UID:
8329
Concept ID:
C0011616
Disease or Syndrome
Synonyms: Contact Dermatitides; Contact Dermatitis; Contact Eczema; Contact Sensitivities; Contact Sensitivity; Dermatitides, Contact; Dermatitis Venenata; Dermatitis, Contact; Eczema, Contact; Sensitivities, Contact; Sensitivity, Contact
SNOMED CT: CD - Contact dermatitis (40275004); Contact eczema (40275004); Contact dermatitis (40275004); Dermatitis venenata (40275004)
 
HPO: HP:0032282
Monarch Initiative: MONDO:0005480

Definition

An inflammatory process in skin caused by an exogenous agent that directly or indirectly injure the skin. If the offending agent is identified and removed, the eruption will resolve. An unusual or patterned eruption may be a clue to the presence of a contact dermatitis. Patch testing may be helpful in the differential diagnosis. [from HPO]

Professional guidelines

PubMed

Thyssen JP, Schuttelaar MLA, Alfonso JH, Andersen KE, Angelova-Fischer I, Arents BWM, Bauer A, Brans R, Cannavo A, Christoffers WA, Crépy MN, Elsner P, Fartasch M, Filon FL, Giménez-Arnau AM, Gonçalo M, Guzmán-Perera MG, Hamann CR, Hoetzenecker W, Johansen JD, John SM, Kunkeler ACM, Hadzavdic SL, Molin S, Nixon R, Oosterhaven JAF, Rustemeyer T, Serra-Baldrich E, Shah M, Simon D, Skudlik C, Spiewak R, Valiukevičienė S, Voorberg AN, Weisshaar E, Agner T
Contact Dermatitis 2022 May;86(5):357-378. Epub 2022 Mar 3 doi: 10.1111/cod.14035. PMID: 34971008
Li Y, Li L
Clin Rev Allergy Immunol 2021 Dec;61(3):245-281. Epub 2021 Jul 15 doi: 10.1007/s12016-021-08875-0. PMID: 34264448
Lugović-Mihić L, Pilipović K, Crnarić I, Šitum M, Duvančić T
Acta Clin Croat 2018 Jun;57(2):342-351. doi: 10.20471/acc.2018.57.02.16. PMID: 30431729Free PMC Article

Recent clinical studies

Etiology

Johnson H, Norman T, Adler BL, Yu J
Cutis 2023 Aug;112(2):78-81. doi: 10.12788/cutis.0825. PMID: 37820332
Bains SN, Nash P, Fonacier L
Clin Rev Allergy Immunol 2019 Feb;56(1):99-109. doi: 10.1007/s12016-018-8713-0. PMID: 30293200
Gru AA, Salavaggione AL
Semin Diagn Pathol 2017 May;34(3):226-236. Epub 2017 Feb 10 doi: 10.1053/j.semdp.2017.02.002. PMID: 28237387
Pigatto PD
Eur Ann Allergy Clin Immunol 2015 Nov;47(6):188-91. PMID: 26549335
Wintzen M, Van Zuuren EJ
Contact Dermatitis 2003 May;48(5):241-3. doi: 10.1034/j.1600-0536.2003.00085.x. PMID: 12868962

Diagnosis

Edwards TM, Usatine RP, Heath CR
Cutis 2023 Oct;112(4):195-197. doi: 10.12788/cutis.0868. PMID: 37988316
Edwards TM, Usatine RP, Heath CR
J Fam Pract 2023 Oct;72(8):350-355. doi: 10.12788/jfp.0678. PMID: 37862625
Li Y, Li L
Clin Rev Allergy Immunol 2021 Dec;61(3):245-281. Epub 2021 Jul 15 doi: 10.1007/s12016-021-08875-0. PMID: 34264448
Brown C, Yu J
Immunol Allergy Clin North Am 2021 Aug;41(3):393-408. Epub 2021 Jun 5 doi: 10.1016/j.iac.2021.04.004. PMID: 34225896
Nat Rev Dis Primers 2021 May 27;7(1):37. doi: 10.1038/s41572-021-00277-y. PMID: 34045453

Therapy

Olbrich H, Sadik CD, Ludwig RJ, Thaçi D, Boch K
Biomolecules 2023 Mar 31;13(4) doi: 10.3390/biom13040634. PMID: 37189381Free PMC Article
Gupta AK, Ravi SP, Vincent K, Abramovits W
Skinmed 2022;20(4):298-300. Epub 2022 Aug 31 PMID: 35976021
Ladda M, Sandhu V, Ighani A, Yeung J
J Cutan Med Surg 2019 Jul/Aug;23(4):442-448. Epub 2019 May 3 doi: 10.1177/1203475419847950. PMID: 31053034
Singh M, Alavi A, Wong R, Akita S
Am J Clin Dermatol 2016 Jun;17(3):277-92. doi: 10.1007/s40257-016-0186-4. PMID: 27021652
Brasch J, Becker D, Aberer W, Bircher A, Kränke B, Denzer-Fürst S, Schnuch A
J Dtsch Dermatol Ges 2007 Oct;5(10):943-51. doi: 10.1111/j.1610-0387.2007.06523.x. PMID: 17910679

Prognosis

Hermida MD, Cabrera HN
Skinmed 2017;15(1):37-42. Epub 2017 Feb 1 PMID: 28270308
Hill H, Jacob SE
Pediatr Dermatol 2016 May;33(3):355-6. Epub 2016 Apr 4 doi: 10.1111/pde.12833. PMID: 27040461
Usatine RP, Riojas M
Am Fam Physician 2010 Aug 1;82(3):249-55. PMID: 20672788
Pigatto P, Martelli A, Marsili C, Fiocchi A
Ital J Pediatr 2010 Jan 13;36:2. doi: 10.1186/1824-7288-36-2. PMID: 20205907Free PMC Article
Friedlander SF
Pediatr Rev 1998 May;19(5):166-71. doi: 10.1542/pir.19-5-166. PMID: 9584526

Clinical prediction guides

Nogueira S, Rodrigues MA, Vender R, Torres T
Dermatol Ther 2022 Dec;35(12):e15931. Epub 2022 Oct 21 doi: 10.1111/dth.15931. PMID: 36226669Free PMC Article
Hon KL, Chu S, Leung AKC
Curr Pediatr Rev 2022;18(3):191-196. doi: 10.2174/1573396317666210901124211. PMID: 34488587
Thélu A, Catoire S, Kerdine-Römer S
Toxicol In Vitro 2020 Feb;62:104691. Epub 2019 Oct 22 doi: 10.1016/j.tiv.2019.104691. PMID: 31648045
Pigatto PD
Eur Ann Allergy Clin Immunol 2015 Nov;47(6):188-91. PMID: 26549335
Trattner A, David M
J Am Acad Dermatol 2005 May;52(5):831-3. doi: 10.1016/j.jaad.2004.12.042. PMID: 15858473

Recent systematic reviews

Olbrich H, Sadik CD, Ludwig RJ, Thaçi D, Boch K
Biomolecules 2023 Mar 31;13(4) doi: 10.3390/biom13040634. PMID: 37189381Free PMC Article
Ramani L, Haidari W, Hall S, Amin S, Chisolm S, Feldman S
J Drugs Dermatol 2023 May 1;22(5):491-495. doi: 10.36849/JDD.4651. PMID: 37133477
Contini M, Hollander MHJ, Vissink A, Schepers RH, Jansma J, Schortinghuis J
Int J Environ Res Public Health 2023 Jan 13;20(2) doi: 10.3390/ijerph20021522. PMID: 36674277Free PMC Article
Crépy MN
Eur J Dermatol 2015 Sep-Oct;25(5):375-83. doi: 10.1684/ejd.2015.2559. PMID: 25905552
Joy NM, Rice KR, Atwater AR
Dermatitis 2013 Sep-Oct;24(5):227-36. doi: 10.1097/DER.0b013e3182a0a19d. PMID: 24030367

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