U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Benign Uveal Neoplasm

MedGen UID:
673328
•Concept ID:
C0686467
•
Neoplastic Process
Synonyms: Benign Neoplasm of the Uvea; Benign Neoplasm of Uvea; Benign neoplasm of uveal tract; Benign Tumor of the Uvea; Benign Tumor of Uvea; Benign Uvea Neoplasm; Benign Uvea Tumor; Benign Uveal Tract Neoplasm; Benign Uveal Tumor
SNOMED CT: Benign neoplasm of uveal tract (92471004)

Definition

A neoplasm that arises from the uvea and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Professional guidelines

PubMed

Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
Update on the diagnosis and treatment of choroidal hemangioma.
García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Proton therapy for the management of uveal melanoma and other ocular tumors.
Mishra KK, Daftari IK
Chin Clin Oncol 2016 Aug;5(4):50. doi: 10.21037/cco.2016.07.06. PMID: 27558251

Recent clinical studies

Etiology

Intraocular schwannoma: case series of 28 patients and literature review.
Dong L, Xu XL, Li HY, Yang Q, Zhang RH, Wei WB, Liu YM
Eye (Lond) 2024 May;38(7):1314-1319. Epub 2024 Jan 2 doi: 10.1038/s41433-023-02890-5. PMID: 38168658Free PMC Article
DOCUMENTATION OF A NEW CHOROIDAL NEVUS.
Parikh R, Gal-Or O, Sakurada Y, Leong B, Freund KB
Retin Cases Brief Rep 2021 May 1;15(3):202-206. doi: 10.1097/ICB.0000000000000822. PMID: 30289791
Multimodal imaging of suspicious choroidal neoplasms in a primary eye-care clinic.
Kaur G, Anthony SA
Clin Exp Optom 2017 Nov;100(6):549-562. Epub 2017 Mar 28 doi: 10.1111/cxo.12537. PMID: 28370509
Recurrent GNAQ mutations in anastomosing hemangiomas.
Bean GR, Joseph NM, Gill RM, Folpe AL, Horvai AE, Umetsu SE
Mod Pathol 2017 May;30(5):722-727. Epub 2017 Jan 13 doi: 10.1038/modpathol.2016.234. PMID: 28084343
Iris melanomas.
Geisse LJ, Robertson DM
Am J Ophthalmol 1985 Jun 15;99(6):638-48. doi: 10.1016/s0002-9394(14)76028-3. PMID: 4014387

Diagnosis

Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
Update on the diagnosis and treatment of choroidal hemangioma.
García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
Choroidal hemangioma.
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
Circumscribed choroidal hemangioma.
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933
Choroidal osteoma.
Kadrmas EF, Weiter JJ
Int Ophthalmol Clin 1997 Fall;37(4):171-82. doi: 10.1097/00004397-199703740-00015. PMID: 9429940

Therapy

DOCUMENTATION OF A NEW CHOROIDAL NEVUS.
Parikh R, Gal-Or O, Sakurada Y, Leong B, Freund KB
Retin Cases Brief Rep 2021 May 1;15(3):202-206. doi: 10.1097/ICB.0000000000000822. PMID: 30289791
INDOLENT, NONPROGRESSIVE, MULTIFOCAL CHOROIDAL LESIONS: A Presumed Benign Choroidal Lymphoid Disease.
Carroll WJ, Deak G, J Daily M, Cunha de Souza E, Shelsta HN, Barbante Casella AM, Jampol LM
Retina 2020 Oct;40(10):1980-1987. doi: 10.1097/IAE.0000000000002865. PMID: 32467483
Circumscribed choroidal hemangioma: A case report and literature review.
Berry M, Lucas LJ
J Optom 2017 Apr-Jun;10(2):79-83. Epub 2016 Feb 10 doi: 10.1016/j.optom.2015.12.006. PMID: 26872405Free PMC Article
Gamma knife radiosurgery for choroidal hemangioma.
Kim YT, Kang SW, Lee JI
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1399-404. Epub 2010 Oct 13 doi: 10.1016/j.ijrobp.2010.08.016. PMID: 20950946
Is observation really appropriate for small choroidal melanomas.
Augsburger JJ
Trans Am Ophthalmol Soc 1993;91:147-68; discussion 169-75. PMID: 8140689Free PMC Article

Prognosis

Update on the diagnosis and treatment of choroidal hemangioma.
García Caride S, Fernández-Vigo JI, Valverde-Megías A
Arch Soc Esp Oftalmol (Engl Ed) 2023 May;98(5):281-291. Epub 2023 Apr 14 doi: 10.1016/j.oftale.2023.04.006. PMID: 37062411
DOCUMENTATION OF A NEW CHOROIDAL NEVUS.
Parikh R, Gal-Or O, Sakurada Y, Leong B, Freund KB
Retin Cases Brief Rep 2021 May 1;15(3):202-206. doi: 10.1097/ICB.0000000000000822. PMID: 30289791
Choroidal hemangioma.
Singh AD, Kaiser PK, Sears JE
Ophthalmol Clin North Am 2005 Mar;18(1):151-61, ix. doi: 10.1016/j.ohc.2004.07.004. PMID: 15763200
The microcirculation of choroidal and ciliary body melanomas.
Folberg R, Mehaffey M, Gardner LM, Meyer M, Rummelt V, Pe'er J
Eye (Lond) 1997;11 ( Pt 2):227-38. doi: 10.1038/eye.1997.57. PMID: 9349418
Iris melanomas.
Geisse LJ, Robertson DM
Am J Ophthalmol 1985 Jun 15;99(6):638-48. doi: 10.1016/s0002-9394(14)76028-3. PMID: 4014387

Clinical prediction guides

CAVITARY CHOROIDAL NEVUS: A CASE REPORT.
Preziosa C, Kashyap BP, Staurenghi G, Pellegrini M
Retin Cases Brief Rep 2022 Nov 1;16(6):674-677. doi: 10.1097/ICB.0000000000001096. PMID: 33229913
Small incision guarded hydroaspiration of iris lesions.
Singh AD
Br J Ophthalmol 2017 Nov;101(11):1570-1575. Epub 2017 Mar 14 doi: 10.1136/bjophthalmol-2016-310093. PMID: 28292778
Circumscribed choroidal hemangioma.
Mashayekhi A, Shields CL
Curr Opin Ophthalmol 2003 Jun;14(3):142-9. doi: 10.1097/00055735-200306000-00006. PMID: 12777933
Choroidal malignant melanoma.
Murphy SF, Mahl CF, Bloom SM
Optom Clin 1993;3(3):63-77. PMID: 8199451
Is observation really appropriate for small choroidal melanomas.
Augsburger JJ
Trans Am Ophthalmol Soc 1993;91:147-68; discussion 169-75. PMID: 8140689Free PMC Article

Recent systematic reviews

Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
Gamma knife radiosurgery for uveal melanomas and metastases: a systematic review and meta-analysis.
Parker T, Rigney G, Kallos J, Stefko ST, Kano H, Niranjan A, Green AL, Aziz T, Rath P, Lunsford LD
Lancet Oncol 2020 Nov;21(11):1526-1536. doi: 10.1016/S1470-2045(20)30459-9. PMID: 33152286

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...