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Soft palate cancer

MedGen UID:
57552
•Concept ID:
C0153376
•
Neoplastic Process
Synonyms: cancer of soft palate; Malignant Neoplasm of Soft Palate; malignant neoplasm of soft palate; Malignant Neoplasm of the Soft Palate; malignant neoplasm of the soft palate; Malignant Soft Palate Neoplasm; malignant soft palate neoplasm; Malignant Soft Palate Tumor; malignant soft palate tumor; malignant soft palate tumour; Malignant tumor of soft palate; Malignant Tumor of Soft Palate; malignant tumor of soft palate; Malignant Tumor of the Soft Palate; malignant tumor of the soft palate; malignant tumour of soft palate; malignant tumour of the soft palate; soft palate cancer
SNOMED CT: Malignant tumor of soft palate (363388009)
 
Monarch Initiative: MONDO:0004611

Definition

A primary or metastatic malignant neoplasm that affects the soft palate. [from NCI]

Professional guidelines

PubMed

Psychosocial Oncology: Optimizing Outcomes through Interdisciplinary Care in Head and Neck Oncology.
Henry M
Curr Oncol 2023 Jul 19;30(7):6859-6861. doi: 10.3390/curroncol30070501. PMID: 37504361Free PMC Article
Implication and Management of Incidental Oropharyngeal Papillomas-A Retrospective Case Series Review.
Kim D, Siegel J, Chouake RJ, Geliebter J, Zalvan CH
Ear Nose Throat J 2021 Aug;100(7):546-551. Epub 2019 Oct 3 doi: 10.1177/0145561319871228. PMID: 31581834
A review of the evaluation and management of velopharyngeal insufficiency in children.
Ruda JM, Krakovitz P, Rose AS
Otolaryngol Clin North Am 2012 Jun;45(3):653-69, viii. doi: 10.1016/j.otc.2012.03.005. PMID: 22588042

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

Recent clinical studies

Etiology

Application of prolonged submental perforator flap to repair the postoperative defect of upper airway malignancy.
Ma H, Zhong Q, Hou L, Feng L, He S, Lian M, Zhao Y, Wang R, Fang J
Eur Arch Otorhinolaryngol 2023 Dec;280(12):5507-5518. Epub 2023 Aug 2 doi: 10.1007/s00405-023-08131-5. PMID: 37530858Free PMC Article
Functional outcomes of soft palate free flap reconstruction following oropharyngeal cancer surgery.
Melan JB, Philouze P, Pradat P, Benzerdjeb N, Blanc J, Ceruse P, Fuchsmann C
Eur J Surg Oncol 2021 Sep;47(9):2265-2271. Epub 2021 May 7 doi: 10.1016/j.ejso.2021.04.044. PMID: 33994058
Techniques and outcomes in microsurgical soft palate reconstruction.
Fries CA, Al Deek N, Wei FC
Head Neck 2019 Jul;41(7):2085-2092. Epub 2019 Jan 28 doi: 10.1002/hed.25662. PMID: 30693590
Advanced soft palate cancer: the clinical importance of the parapharyngeal space.
Douglas WG, Rigual NR, Giese W, Bauer J, Wiseman SM, Loree TR, Schwarz J, Alrawi S, Hicks WL Jr
Otolaryngol Head Neck Surg 2005 Jul;133(1):66-9. doi: 10.1016/j.otohns.2005.03.007. PMID: 16025055

Diagnosis

Cardiac metastasis of head and neck squamous cell carcinoma.
Nagata S, Ota K, Nagata M, Shinohara M
Int J Oral Maxillofac Surg 2012 Dec;41(12):1458-62. Epub 2012 Aug 24 doi: 10.1016/j.ijom.2012.07.017. PMID: 22921451

Therapy

Interstitial and external radiotherapy in carcinoma of the soft palate and uvula.
Esche BA, Haie CM, Gerbaulet AP, Eschwege F, Richard JM, Chassagne D
Int J Radiat Oncol Biol Phys 1988 Sep;15(3):619-25. doi: 10.1016/0360-3016(88)90303-3. PMID: 3138213

Prognosis

Functional outcomes of soft palate free flap reconstruction following oropharyngeal cancer surgery.
Melan JB, Philouze P, Pradat P, Benzerdjeb N, Blanc J, Ceruse P, Fuchsmann C
Eur J Surg Oncol 2021 Sep;47(9):2265-2271. Epub 2021 May 7 doi: 10.1016/j.ejso.2021.04.044. PMID: 33994058
Cardiac metastasis of head and neck squamous cell carcinoma.
Nagata S, Ota K, Nagata M, Shinohara M
Int J Oral Maxillofac Surg 2012 Dec;41(12):1458-62. Epub 2012 Aug 24 doi: 10.1016/j.ijom.2012.07.017. PMID: 22921451
Advanced soft palate cancer: the clinical importance of the parapharyngeal space.
Douglas WG, Rigual NR, Giese W, Bauer J, Wiseman SM, Loree TR, Schwarz J, Alrawi S, Hicks WL Jr
Otolaryngol Head Neck Surg 2005 Jul;133(1):66-9. doi: 10.1016/j.otohns.2005.03.007. PMID: 16025055

Clinical prediction guides

Application of prolonged submental perforator flap to repair the postoperative defect of upper airway malignancy.
Ma H, Zhong Q, Hou L, Feng L, He S, Lian M, Zhao Y, Wang R, Fang J
Eur Arch Otorhinolaryngol 2023 Dec;280(12):5507-5518. Epub 2023 Aug 2 doi: 10.1007/s00405-023-08131-5. PMID: 37530858Free PMC Article
Functional outcomes of soft palate free flap reconstruction following oropharyngeal cancer surgery.
Melan JB, Philouze P, Pradat P, Benzerdjeb N, Blanc J, Ceruse P, Fuchsmann C
Eur J Surg Oncol 2021 Sep;47(9):2265-2271. Epub 2021 May 7 doi: 10.1016/j.ejso.2021.04.044. PMID: 33994058
Techniques and outcomes in microsurgical soft palate reconstruction.
Fries CA, Al Deek N, Wei FC
Head Neck 2019 Jul;41(7):2085-2092. Epub 2019 Jan 28 doi: 10.1002/hed.25662. PMID: 30693590
Gene mutations in the D-loop region of mitochondrial DNA in oral squamous cell carcinoma.
Yuan RT, Sun Y, Bu LX, Jia MY
Mol Med Rep 2015 Jun;11(6):4496-500. Epub 2015 Jan 22 doi: 10.3892/mmr.2015.3240. PMID: 25625701
Modified folding radial forearm flap in soft palate and tonsillar fossa reconstruction.
Kang HG, Park MC, Lim H, Kim JH, Lee IJ
J Craniofac Surg 2013 Mar;24(2):458-60. doi: 10.1097/SCS.0b013e31826cfecf. PMID: 23524714

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    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Head and Neck Cancers, 2024

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
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      Related literature resources in PubMed

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