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Adult Classic Hodgkin Lymphoma

MedGen UID:
389532
Concept ID:
C2347747
Neoplastic Process
Synonym: Adult Classical Hodgkin Lymphoma

Definition

Classic Hodgkin lymphoma that occurs in adults. [from NCI]

Professional guidelines

PubMed

Al-Juhaishi T, Ahmed S
Hematology Am Soc Hematol Educ Program 2023 Dec 8;2023(1):500-509. doi: 10.1182/hematology.2023000511. PMID: 38066938Free PMC Article
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Engert A
Hematol Oncol 2019 Jun;37 Suppl 1:92-94. doi: 10.1002/hon.2590. PMID: 31187519

Recent clinical studies

Etiology

Kelly KM, Friedberg JW
J Clin Oncol 2024 Feb 20;42(6):653-664. Epub 2023 Nov 20 doi: 10.1200/JCO.23.01799. PMID: 37983570
Munir F, Hardit V, Sheikh IN, AlQahtani S, He J, Cuglievan B, Hosing C, Tewari P, Khazal S
Int J Mol Sci 2023 Jun 13;24(12) doi: 10.3390/ijms241210095. PMID: 37373245Free PMC Article
Advani RH, Moskowitz AJ, Bartlett NL, Vose JM, Ramchandren R, Feldman TA, LaCasce AS, Christian BA, Ansell SM, Moskowitz CH, Brown L, Zhang C, Taft D, Ansari S, Sacchi M, Ho L, Herrera AF
Blood 2021 Aug 12;138(6):427-438. doi: 10.1182/blood.2020009178. PMID: 33827139
Eichenauer DA, Engert A
Blood 2020 Dec 24;136(26):2987-2993. doi: 10.1182/blood.2019004044. PMID: 32877522
Armand P, Engert A, Younes A, Fanale M, Santoro A, Zinzani PL, Timmerman JM, Collins GP, Ramchandren R, Cohen JB, De Boer JP, Kuruvilla J, Savage KJ, Trneny M, Shipp MA, Kato K, Sumbul A, Farsaci B, Ansell SM
J Clin Oncol 2018 May 10;36(14):1428-1439. Epub 2018 Mar 27 doi: 10.1200/JCO.2017.76.0793. PMID: 29584546Free PMC Article

Diagnosis

Kahn J, Dabaja B, Wu S, Kelly K, Berkahn L, Pavlovsky A, Sureda A, LaCasce A
Hematol Oncol 2024 Nov;42(6):e3239. Epub 2023 Dec 1 doi: 10.1002/hon.3239. PMID: 38037872
Eichenauer DA, Engert A
Blood 2020 Dec 24;136(26):2987-2993. doi: 10.1182/blood.2019004044. PMID: 32877522
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Ansell SM
Am J Hematol 2020 Aug;95(8):978-989. Epub 2020 Jun 8 doi: 10.1002/ajh.25856. PMID: 32384177
Fan Z, Natkunam Y, Bair E, Tibshirani R, Warnke RA
Am J Surg Pathol 2003 Oct;27(10):1346-56. doi: 10.1097/00000478-200310000-00007. PMID: 14508396

Therapy

Herrera AF, LeBlanc M, Castellino SM, Li H, Rutherford SC, Evens AM, Davison K, Punnett A, Parsons SK, Ahmed S, Casulo C, Bartlett NL, Tuscano JM, Mei MG, Hess BT, Jacobs R, Saeed H, Torka P, Hu B, Moskowitz C, Kaur S, Goyal G, Forlenza C, Doan A, Lamble A, Kumar P, Chowdhury S, Brinker B, Sharma N, Singh A, Blum KA, Perry AM, Kovach A, Hodgson D, Constine LS, Shields LK, Prica A, Dillon H, Little RF, Shipp MA, Crump M, Kahl B, Leonard JP, Smith SM, Song JY, Kelly KM, Friedberg JW
N Engl J Med 2024 Oct 17;391(15):1379-1389. doi: 10.1056/NEJMoa2405888. PMID: 39413375Free PMC Article
Munir F, Hardit V, Sheikh IN, AlQahtani S, He J, Cuglievan B, Hosing C, Tewari P, Khazal S
Int J Mol Sci 2023 Jun 13;24(12) doi: 10.3390/ijms241210095. PMID: 37373245Free PMC Article
Harker-Murray P, Mauz-Körholz C, Leblanc T, Mascarin M, Michel G, Cooper S, Beishuizen A, Leger KJ, Amoroso L, Buffardi S, Rigaud C, Hoppe BS, Lisano J, Francis S, Sacchi M, Cole PD, Drachtman RA, Kelly KM, Daw S
Blood 2023 Apr 27;141(17):2075-2084. doi: 10.1182/blood.2022017118. PMID: 36564047Free PMC Article
Kuruvilla J, Ramchandren R, Santoro A, Paszkiewicz-Kozik E, Gasiorowski R, Johnson NA, Fogliatto LM, Goncalves I, de Oliveira JSR, Buccheri V, Perini GF, Goldschmidt N, Kriachok I, Dickinson M, Komarnicki M, McDonald A, Ozcan M, Sekiguchi N, Zhu Y, Nahar A, Marinello P, Zinzani PL; KEYNOTE-204 investigators
Lancet Oncol 2021 Apr;22(4):512-524. Epub 2021 Mar 12 doi: 10.1016/S1470-2045(21)00005-X. PMID: 33721562
Evens AM, Advani RH, Helenowski IB, Fanale M, Smith SM, Jovanovic BD, Bociek GR, Klein AK, Winter JN, Gordon LI, Hamlin PA
J Clin Oncol 2018 Oct 20;36(30):3015-3022. Epub 2018 Sep 4 doi: 10.1200/JCO.2018.79.0139. PMID: 30179569

Prognosis

Munir F, Hardit V, Sheikh IN, AlQahtani S, He J, Cuglievan B, Hosing C, Tewari P, Khazal S
Int J Mol Sci 2023 Jun 13;24(12) doi: 10.3390/ijms241210095. PMID: 37373245Free PMC Article
Advani RH, Moskowitz AJ, Bartlett NL, Vose JM, Ramchandren R, Feldman TA, LaCasce AS, Christian BA, Ansell SM, Moskowitz CH, Brown L, Zhang C, Taft D, Ansari S, Sacchi M, Ho L, Herrera AF
Blood 2021 Aug 12;138(6):427-438. doi: 10.1182/blood.2020009178. PMID: 33827139
Eichenauer DA, Engert A
Blood 2020 Dec 24;136(26):2987-2993. doi: 10.1182/blood.2019004044. PMID: 32877522
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Armand P, Engert A, Younes A, Fanale M, Santoro A, Zinzani PL, Timmerman JM, Collins GP, Ramchandren R, Cohen JB, De Boer JP, Kuruvilla J, Savage KJ, Trneny M, Shipp MA, Kato K, Sumbul A, Farsaci B, Ansell SM
J Clin Oncol 2018 May 10;36(14):1428-1439. Epub 2018 Mar 27 doi: 10.1200/JCO.2017.76.0793. PMID: 29584546Free PMC Article

Clinical prediction guides

Herrera AF, LeBlanc M, Castellino SM, Li H, Rutherford SC, Evens AM, Davison K, Punnett A, Parsons SK, Ahmed S, Casulo C, Bartlett NL, Tuscano JM, Mei MG, Hess BT, Jacobs R, Saeed H, Torka P, Hu B, Moskowitz C, Kaur S, Goyal G, Forlenza C, Doan A, Lamble A, Kumar P, Chowdhury S, Brinker B, Sharma N, Singh A, Blum KA, Perry AM, Kovach A, Hodgson D, Constine LS, Shields LK, Prica A, Dillon H, Little RF, Shipp MA, Crump M, Kahl B, Leonard JP, Smith SM, Song JY, Kelly KM, Friedberg JW
N Engl J Med 2024 Oct 17;391(15):1379-1389. doi: 10.1056/NEJMoa2405888. PMID: 39413375Free PMC Article
Harker-Murray P, Mauz-Körholz C, Leblanc T, Mascarin M, Michel G, Cooper S, Beishuizen A, Leger KJ, Amoroso L, Buffardi S, Rigaud C, Hoppe BS, Lisano J, Francis S, Sacchi M, Cole PD, Drachtman RA, Kelly KM, Daw S
Blood 2023 Apr 27;141(17):2075-2084. doi: 10.1182/blood.2022017118. PMID: 36564047Free PMC Article
Connors JM, Cozen W, Steidl C, Carbone A, Hoppe RT, Flechtner HH, Bartlett NL
Nat Rev Dis Primers 2020 Jul 23;6(1):61. doi: 10.1038/s41572-020-0189-6. PMID: 32703953
Evens AM, Advani RH, Helenowski IB, Fanale M, Smith SM, Jovanovic BD, Bociek GR, Klein AK, Winter JN, Gordon LI, Hamlin PA
J Clin Oncol 2018 Oct 20;36(30):3015-3022. Epub 2018 Sep 4 doi: 10.1200/JCO.2018.79.0139. PMID: 30179569
Fan Z, Natkunam Y, Bair E, Tibshirani R, Warnke RA
Am J Surg Pathol 2003 Oct;27(10):1346-56. doi: 10.1097/00000478-200310000-00007. PMID: 14508396

Recent systematic reviews

El Fakih R, Bajuaifer YS, Shah AY, Sulaiman R, Almohamady R, ELGohary G, Alothaimeen HS, Aljurf M
Ann Hematol 2024 Apr;103(4):1131-1137. Epub 2023 Jul 10 doi: 10.1007/s00277-023-05357-5. PMID: 37428199
Campana IG, Silva GD
Cerebellum 2022 Dec;21(6):1085-1091. Epub 2021 Nov 24 doi: 10.1007/s12311-021-01346-4. PMID: 34817790
Allen PB, Ayers A, Behera M, Evens AM, Flowers C
Leuk Lymphoma 2020 Jul;61(7):1555-1564. Epub 2020 Feb 26 doi: 10.1080/10428194.2020.1731497. PMID: 32102579
Goldkuhle M, Dimaki M, Gartlehner G, Monsef I, Dahm P, Glossmann JP, Engert A, von Tresckow B, Skoetz N
Cochrane Database Syst Rev 2018 Jul 12;7(7):CD012556. doi: 10.1002/14651858.CD012556.pub2. PMID: 30001476Free PMC Article
Saini KS, Azim HA Jr, Cocorocchio E, Vanazzi A, Saini ML, Raviele PR, Pruneri G, Peccatori FA
Cancer Treat Rev 2011 Aug;37(5):385-90. Epub 2010 Dec 22 doi: 10.1016/j.ctrv.2010.11.005. PMID: 21183282

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