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Paranasal sinus lymphoma

MedGen UID:
277498
•Concept ID:
C1335339
•
Neoplastic Process
Synonyms: Accessory Sinus Lymphoma; accessory sinus lymphoma; Lymphoma of Accessory Sinus; lymphoma of accessory sinus; Lymphoma of Paranasal Sinus; lymphoma of paranasal sinus; Lymphoma of the Accessory Sinus; lymphoma of the accessory sinus; Lymphoma of the Paranasal Sinus; lymphoma of the paranasal sinus; Paranasal Sinus Lymphoma; paranasal sinus lymphoma; Primary Paranasal Sinus Lymphoma; primary paranasal sinus lymphoma
 
Monarch Initiative: MONDO:0001743

Definition

A lymphoma that arises from the paranasal sinus. Representative examples include diffuse large B-cell lymphoma and extranodal NK/T-cell lymphoma, nasal type. [from NCI]

Professional guidelines

PubMed

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors.
Kuan EC, Wang EW, Adappa ND, Beswick DM, London NR Jr, Su SY, Wang MB, Abuzeid WM, Alexiev B, Alt JA, Antognoni P, Alonso-Basanta M, Batra PS, Bhayani M, Bell D, Bernal-Sprekelsen M, Betz CS, Blay JY, Bleier BS, Bonilla-Velez J, Callejas C, Carrau RL, Casiano RR, Castelnuovo P, Chandra RK, Chatzinakis V, Chen SB, Chiu AG, Choby G, Chowdhury NI, Citardi MJ, Cohen MA, Dagan R, Dalfino G, Dallan I, Dassi CS, de Almeida J, Dei Tos AP, DelGaudio JM, Ebert CS, El-Sayed IH, Eloy JA, Evans JJ, Fang CH, Farrell NF, Ferrari M, Fischbein N, Folbe A, Fokkens WJ, Fox MG, Lund VJ, Gallia GL, Gardner PA, Geltzeiler M, Georgalas C, Getz AE, Govindaraj S, Gray ST, Grayson JW, Gross BA, Grube JG, Guo R, Ha PK, Halderman AA, Hanna EY, Harvey RJ, Hernandez SC, Holtzman AL, Hopkins C, Huang Z, Huang Z, Humphreys IM, Hwang PH, Iloreta AM, Ishii M, Ivan ME, Jafari A, Kennedy DW, Khan M, Kimple AJ, Kingdom TT, Knisely A, Kuo YJ, Lal D, Lamarre ED, Lan MY, Le H, Lechner M, Lee NY, Lee JK, Lee VH, Levine CG, Lin JC, Lin DT, Lobo BC, Locke T, Luong AU, Magliocca KR, Markovic SN, Matnjani G, McKean EL, Meço C, Mendenhall WM, Michel L, Na'ara S, Nicolai P, Nuss DW, Nyquist GG, Oakley GM, Omura K, Orlandi RR, Otori N, Papagiannopoulos P, Patel ZM, Pfister DG, Phan J, Psaltis AJ, Rabinowitz MR, Ramanathan M Jr, Rimmer R, Rosen MR, Sanusi O, Sargi ZB, Schafhausen P, Schlosser RJ, Sedaghat AR, Senior BA, Shrivastava R, Sindwani R, Smith TL, Smith KA, Snyderman CH, Solares CA, Sreenath SB, Stamm A, Stölzel K, Sumer B, Surda P, Tajudeen BA, Thompson LDR, Thorp BD, Tong CCL, Tsang RK, Turner JH, Turri-Zanoni M, Udager AM, van Zele T, VanKoevering K, Welch KC, Wise SK, Witterick IJ, Won TB, Wong SN, Woodworth BA, Wormald PJ, Yao WC, Yeh CF, Zhou B, Palmer JN
Int Forum Allergy Rhinol 2024 Feb;14(2):149-608. Epub 2024 Jan 2 doi: 10.1002/alr.23262. PMID: 37658764
The contemporary management of cancers of the sinonasal tract in adults.
Thawani R, Kim MS, Arastu A, Feng Z, West MT, Taflin NF, Thein KZ, Li R, Geltzeiler M, Lee N, Fuller CD, Grandis JR, Floudas CS, Heinrich MC, Hanna E, Chandra RA
CA Cancer J Clin 2023 Jan;73(1):72-112. Epub 2022 Aug 2 doi: 10.3322/caac.21752. PMID: 35916666Free PMC Article
Radiotherapy of sinonasal cancers.
Larnaudie A, Delaby N, Marcy PY, Leleu T, Costes-Martineau V, Vergez S, de Gabory L, Quintyn JC, Doré M, Pointreau Y, Thariat J
Cancer Radiother 2022 Feb-Apr;26(1-2):156-167. Epub 2021 Dec 22 doi: 10.1016/j.canrad.2021.10.007. PMID: 34953697

Recent clinical studies

Etiology

Paranasal sinus lymphoma: Retrospective review with focus on clinical features, histopathology, prognosis, and relationship to systemic lymphoma.
Wajda BN, Rabinowitz MR, Nyquist GG, Mardekian SK, Rosen MR, Rabinowitz MP
Head Neck 2017 Jun;39(6):1065-1070. Epub 2017 Mar 24 doi: 10.1002/hed.24686. PMID: 28339134
Extranodal natural killer/T-Cell lymphoma: A population-based comparison of sinonasal and extranasal disease.
Vazquez A, Khan MN, Blake DM, Sanghvi S, Baredes S, Eloy JA
Laryngoscope 2014 Apr;124(4):888-95. Epub 2013 Oct 7 doi: 10.1002/lary.24371. PMID: 24114591
Primary paranasal sinus lymphoma: natural history and improved outcome with central nervous system chemoprophylaxis.
Laskin JJ, Savage KJ, Voss N, Gascoyne RD, Connors JM
Leuk Lymphoma 2005 Dec;46(12):1721-7. doi: 10.1080/17402520500182345. PMID: 16263574
Treatment of lethal midline granuloma type nasal T-cell lymphoma.
Sakata K, Hareyama M, Ohuchi A, Sido M, Nagakura H, Morita K, Harabuchi Y, Kataura A
Acta Oncol 1997;36(3):307-11. doi: 10.3109/02841869709001268. PMID: 9208902

Diagnosis

Paranasal sinus lymphoma: Retrospective review with focus on clinical features, histopathology, prognosis, and relationship to systemic lymphoma.
Wajda BN, Rabinowitz MR, Nyquist GG, Mardekian SK, Rosen MR, Rabinowitz MP
Head Neck 2017 Jun;39(6):1065-1070. Epub 2017 Mar 24 doi: 10.1002/hed.24686. PMID: 28339134
Primary diffuse large B-cell non-Hodgkin lymphoma of the paranasal sinuses presenting as cavernous sinus syndrome.
Lee H, Choi KE, Park M, Lee SH, Baek S
J Craniofac Surg 2014 Jul;25(4):e338-9. doi: 10.1097/SCS.0000000000000597. PMID: 25006937
Extranodal natural killer/T-Cell lymphoma: A population-based comparison of sinonasal and extranasal disease.
Vazquez A, Khan MN, Blake DM, Sanghvi S, Baredes S, Eloy JA
Laryngoscope 2014 Apr;124(4):888-95. Epub 2013 Oct 7 doi: 10.1002/lary.24371. PMID: 24114591
Secondary intraocular uveal involvement by primary paranasal sinus lymphoma.
Corrêa ZM, Augsburger JJ, Dalal MD, Spaulding A
Int Ophthalmol 2012 Aug;32(4):397-400. Epub 2012 May 13 doi: 10.1007/s10792-012-9570-0. PMID: 22581320
Primary paranasal sinus lymphoma: natural history and improved outcome with central nervous system chemoprophylaxis.
Laskin JJ, Savage KJ, Voss N, Gascoyne RD, Connors JM
Leuk Lymphoma 2005 Dec;46(12):1721-7. doi: 10.1080/17402520500182345. PMID: 16263574

Therapy

Primary paranasal sinus lymphoma: natural history and improved outcome with central nervous system chemoprophylaxis.
Laskin JJ, Savage KJ, Voss N, Gascoyne RD, Connors JM
Leuk Lymphoma 2005 Dec;46(12):1721-7. doi: 10.1080/17402520500182345. PMID: 16263574
Brief chemotherapy, involved field radiation therapy, and central nervous system prophylaxis for paranasal sinus lymphoma.
Cooper DL, Ginsberg SS
Cancer 1992 Jun 15;69(12):2888-93. doi: 10.1002/1097-0142(19920615)69:12<2888::aid-cncr2820691205>3.0.co;2-d. PMID: 1375527
Optic neuropathy associated with chronic lymphomatous meningitis.
Coppeto JR, Monteiro ML, Cannarozzi DB
J Clin Neuroophthalmol 1988 Mar;8(1):39-45. PMID: 2972750

Prognosis

Paranasal sinus lymphoma: Retrospective review with focus on clinical features, histopathology, prognosis, and relationship to systemic lymphoma.
Wajda BN, Rabinowitz MR, Nyquist GG, Mardekian SK, Rosen MR, Rabinowitz MP
Head Neck 2017 Jun;39(6):1065-1070. Epub 2017 Mar 24 doi: 10.1002/hed.24686. PMID: 28339134
Extranodal natural killer/T-Cell lymphoma: A population-based comparison of sinonasal and extranasal disease.
Vazquez A, Khan MN, Blake DM, Sanghvi S, Baredes S, Eloy JA
Laryngoscope 2014 Apr;124(4):888-95. Epub 2013 Oct 7 doi: 10.1002/lary.24371. PMID: 24114591
Primary diffuse large B-cell lymphoma of the ethmoido-orbital region.
Catalfamo L, Nava C, Matyasova J, De Ponte FS
J Craniofac Surg 2013 Nov;24(6):e602-4. doi: 10.1097/SCS.0b013e3182a28b99. PMID: 24220479
Orbital invasion of frontal sinus lymphoma.
Nemet AY, Deckel Y, Kourt G
Orbit 2006 Jun;25(2):149-51. doi: 10.1080/01676830600575592. PMID: 16754228
Primary paranasal sinus lymphoma: natural history and improved outcome with central nervous system chemoprophylaxis.
Laskin JJ, Savage KJ, Voss N, Gascoyne RD, Connors JM
Leuk Lymphoma 2005 Dec;46(12):1721-7. doi: 10.1080/17402520500182345. PMID: 16263574

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