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Major salivary gland adenoid cystic carcinoma

MedGen UID:
235286
Concept ID:
C1334548
Neoplastic Process
Synonyms: Adenoid Cystic Carcinoma of Major Salivary Gland; adenoid cystic carcinoma of major salivary gland; Adenoid Cystic Carcinoma of the Major Salivary Gland; adenoid cystic carcinoma of the major salivary gland; major salivary gland adenoid cystic cancer; Major Salivary Gland Adenoid Cystic Carcinoma; major salivary gland adenoid cystic carcinoma
 
Monarch Initiative: MONDO:0045063

Definition

An aggressive carcinoma that arises from the major salivary glands. It is characterized by the presence of malignant epithelial and myoepithelial cells forming cribriform, tubular, and solid patterns. It usually presents as a slow growing mass. Patients develop pain because of the tendency of these carcinomas to invade perineural tissues. [from NCI]

Professional guidelines

PubMed

Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Walvekar R, Phalke NP
Otolaryngol Clin North Am 2021 Jun;54(3):629-639. doi: 10.1016/j.otc.2021.02.011. PMID: 34024489
Wang X, Luo Y, Li M, Yan H, Sun M, Fan T
Oncotarget 2017 Jan 17;8(3):3946-3956. doi: 10.18632/oncotarget.13952. PMID: 27992367Free PMC Article

Recent clinical studies

Etiology

Qian ZJ, Chen MM, Divi V, Megwalu UC
Head Neck 2019 Jun;41(6):1903-1907. Epub 2019 Jan 8 doi: 10.1002/hed.25628. PMID: 30620437Free PMC Article
Megwalu UC, Sirjani D
Otolaryngol Head Neck Surg 2017 Apr;156(4):660-664. Epub 2017 Feb 7 doi: 10.1177/0194599817690138. PMID: 28168897
INTERNATIONAL HEAD AND NECK SCIENTIFIC GROUP
J Laryngol Otol 2017 Feb;131(2):96-105. Epub 2016 Dec 15 doi: 10.1017/S0022215116009749. PMID: 27974071

Diagnosis

Su HZ, Zhang F, Zhang XD, Hong LC, Huang SJ, Su YQ, Su YM
J Ultrasound Med 2023 Feb;42(3):603-611. Epub 2022 Jun 20 doi: 10.1002/jum.16043. PMID: 35722660
Megwalu UC, Sirjani D
Otolaryngol Head Neck Surg 2017 Apr;156(4):660-664. Epub 2017 Feb 7 doi: 10.1177/0194599817690138. PMID: 28168897
Netto Jde N, Miranda AM, da Silveira HM, dos Santos TC, Pires FR
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008 Aug;106(2):242-5. doi: 10.1016/j.tripleo.2008.04.015. PMID: 18644520

Prognosis

Su HZ, Zhang F, Zhang XD, Hong LC, Huang SJ, Su YQ, Su YM
J Ultrasound Med 2023 Feb;42(3):603-611. Epub 2022 Jun 20 doi: 10.1002/jum.16043. PMID: 35722660
Qian ZJ, Chen MM, Divi V, Megwalu UC
Head Neck 2019 Jun;41(6):1903-1907. Epub 2019 Jan 8 doi: 10.1002/hed.25628. PMID: 30620437Free PMC Article

Clinical prediction guides

Su HZ, Zhang F, Zhang XD, Hong LC, Huang SJ, Su YQ, Su YM
J Ultrasound Med 2023 Feb;42(3):603-611. Epub 2022 Jun 20 doi: 10.1002/jum.16043. PMID: 35722660

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