U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Subglottis carcinoma

MedGen UID:
226968
•Concept ID:
C1299239
•
Neoplastic Process
Synonyms: Cancer of Subglottis; Cancer of the Subglottis; Carcinoma of subglottis; Carcinoma of Subglottis; carcinoma of subglottis; Carcinoma of the Subglottis; carcinoma of the subglottis; Subglottic Cancer; Subglottic Carcinoma; subglottic carcinoma; Subglottis Carcinoma; subglottis carcinoma
SNOMED CT: Carcinoma of subglottis (372104008)
 
Monarch Initiative: MONDO:0004358

Definition

A carcinoma of the larynx that arises from the subglottic area. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSubglottis carcinoma

Professional guidelines

PubMed

Neck management in patients undergoing postradiotherapy salvage laryngeal surgery for recurrent/persistent laryngeal cancer.
Farrag TY, Lin FR, Cummings CW, Koch WM, Flint PW, Califano JA, Broussard J, Bajaj G, Tufano RP
Laryngoscope 2006 Oct;116(10):1864-6. doi: 10.1097/01.mlg.0000234917.08822.cd. PMID: 17003711
Surgical treatment of laryngeal carcinoma with subglottis involvement.
Chiesa F, Tradati N, Calabrese L, Zurrida S, DePaoli F, Costa L, Molinari R
Oncol Rep 2001 Jan-Feb;8(1):137-40. PMID: 11115585
The pathology and management of subglottic cancer.
Ferlito A, Rinaldo A
Eur Arch Otorhinolaryngol 2000;257(3):168-73. doi: 10.1007/s004050050217. PMID: 10839493

Recent clinical studies

Etiology

Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Epidemiological, clinical and oncological outcomes of young patients with laryngeal cancer: a systematic review.
Lechien JR, Maniaci A, Hans S, Iannella G, Fakhry N, Mayo-Yáñez M, Ayad T, Mannelli G, Chiesa-Estomba CM
Eur Arch Otorhinolaryngol 2022 Dec;279(12):5741-5753. Epub 2022 Jun 2 doi: 10.1007/s00405-022-07466-9. PMID: 35652941
Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Laryngotracheal Microbiota in Adult Laryngotracheal Stenosis.
Hillel AT, Tang SS, Carlos C, Skarlupka JH, Gowda M, Yin LX, Motz K, Currie CR, Suen G, Thibeault SL
mSphere 2019 May 1;4(3) doi: 10.1128/mSphereDirect.00211-19. PMID: 31043518Free PMC Article
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197

Diagnosis

Prognosis of subglottic carcinoma: Is it really worse?
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A
Head Neck 2019 Feb;41(2):511-521. Epub 2018 Jun 26 doi: 10.1002/hed.25172. PMID: 29947111
Epithelial-myoepithelial carcinoma arising from the subglottis: a case report and review of the literature.
Oh HJ, Do NY, Kee KH, Park JH
J Med Case Rep 2016 Feb 27;10:45. doi: 10.1186/s13256-016-0824-8. PMID: 26922486Free PMC Article
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review.
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176
Subglottic Basal Cell Adenocarcinoma.
Loochtan MJ, Shaar M, Pambuccian S, Borrowdale RW
Ann Otol Rhinol Laryngol 2016 Feb;125(2):169-72. Epub 2015 Sep 7 doi: 10.1177/0003489415603720. PMID: 26346279
Elective superior mediastinal dissection for laryngeal carcinoma involving subglottis.
Dogan E, Yuksel Aslier NG, Cetinayak HO, Erdag TK, Sarioglu S, Ikiz AO
Acta Otolaryngol 2014 Dec;134(12):1275-80. Epub 2014 Oct 21 doi: 10.3109/00016489.2014.952335. PMID: 25331522

Therapy

Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Advances in Organ Preservation for Laryngeal Cancer.
Campbell G, Glazer TA, Kimple RJ, Bruce JY
Curr Treat Options Oncol 2022 Apr;23(4):594-608. Epub 2022 Mar 18 doi: 10.1007/s11864-022-00945-5. PMID: 35303749Free PMC Article
Non-epithelial tumors of the larynx: case series of 12 years.
Saraydaroglu O, Narter S, Ozsen M, Coskun H
Eur Arch Otorhinolaryngol 2019 Oct;276(10):2843-2847. Epub 2019 Jun 29 doi: 10.1007/s00405-019-05527-0. PMID: 31256243
Study of the Histopathologic Characteristics and Surface Morphologies of Glottic Carcinomas With Anterior Vocal Commissure Involvement.
Wu J, Zhao J, Wang Z, Li Z, Luo J, Liao B, Yang Z, Liu Q, Wang B, Wen W, Lei W
Medicine (Baltimore) 2015 Jul;94(29):e1169. doi: 10.1097/MD.0000000000001169. PMID: 26200618Free PMC Article
Management of acute and chronic disorders of the trachea and subglottis.
Brooks R, Bartlett RH, Gazzaniga AB
Am J Surg 1985 Jul;150(1):24-31. doi: 10.1016/0002-9610(85)90005-4. PMID: 3893182

Prognosis

Malignant Minor Salivary gland neoplasms ofLarynx: Our Experience.
Joshi P, Bhattacharya K, Menon MB, Ghosh Laskar S, Joshi A, Patil V, Chaturvedi P
Otolaryngol Pol 2023 Sep 29;77(5):1-7. doi: 10.5604/01.3001.0053.4040. PMID: 38032326
Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Prognosis of subglottic carcinoma: Is it really worse?
Coskun H, Mendenhall WM, Rinaldo A, Rodrigo JP, Suárez C, Strojan P, López F, Mondin V, Saba NF, Shaha AR, Smee R, Takes RP, Ferlito A
Head Neck 2019 Feb;41(2):511-521. Epub 2018 Jun 26 doi: 10.1002/hed.25172. PMID: 29947111
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197
Peristomal recurrence.
Hosal IN, Onerci M, Turan E
Am J Otolaryngol 1993 May-Jun;14(3):206-8. doi: 10.1016/0196-0709(93)90031-2. PMID: 8338204

Clinical prediction guides

The nonsurgical management of early stage (T1/2 N0 M0) laryngeal cancer: A population analysis.
Lee KC, Chuang SK
Oral Surg Oral Med Oral Pathol Oral Radiol 2020 Jul;130(1):18-24. Epub 2020 May 30 doi: 10.1016/j.oooo.2020.01.006. PMID: 32487468
Laryngotracheal Microbiota in Adult Laryngotracheal Stenosis.
Hillel AT, Tang SS, Carlos C, Skarlupka JH, Gowda M, Yin LX, Motz K, Currie CR, Suen G, Thibeault SL
mSphere 2019 May 1;4(3) doi: 10.1128/mSphereDirect.00211-19. PMID: 31043518Free PMC Article
Subglottic Squamous Cell Carcinoma: A Population-Based Study of 889 Cases.
Marchiano E, Patel DM, Patel TD, Patel AA, Xue YE, Eloy JA, Baredes S, Park RC
Otolaryngol Head Neck Surg 2016 Feb;154(2):315-21. Epub 2015 Nov 25 doi: 10.1177/0194599815618190. PMID: 26607281
Elective superior mediastinal dissection for laryngeal carcinoma involving subglottis.
Dogan E, Yuksel Aslier NG, Cetinayak HO, Erdag TK, Sarioglu S, Ikiz AO
Acta Otolaryngol 2014 Dec;134(12):1275-80. Epub 2014 Oct 21 doi: 10.3109/00016489.2014.952335. PMID: 25331522
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197

Recent systematic reviews

Paratracheal lymph node dissection during total (pharyngo-)laryngectomy: A systematic review and meta-analysis.
Chabrillac E, Jackson R, Mattei P, D'Andréa G, Vergez S, Dupret-Bories A, Edafe O
Oral Oncol 2022 Sep;132:106017. Epub 2022 Jul 10 doi: 10.1016/j.oraloncology.2022.106017. PMID: 35830760
Epidemiological, clinical and oncological outcomes of young patients with laryngeal cancer: a systematic review.
Lechien JR, Maniaci A, Hans S, Iannella G, Fakhry N, Mayo-Yáñez M, Ayad T, Mannelli G, Chiesa-Estomba CM
Eur Arch Otorhinolaryngol 2022 Dec;279(12):5741-5753. Epub 2022 Jun 2 doi: 10.1007/s00405-022-07466-9. PMID: 35652941
Laryngeal Adenoid Cystic Carcinoma: A Systematic Review.
Marchiano E, Chin OY, Fang CH, Park RC, Baredes S, Eloy JA
Otolaryngol Head Neck Surg 2016 Mar;154(3):433-9. Epub 2015 Dec 23 doi: 10.1177/0194599815621884. PMID: 26701176
Thyroid gland invasion in total laryngectomy and total laryngopharyngectomy: a systematic review and meta-analysis of the English literature.
Kumar R, Drinnan M, Robinson M, Meikle D, Stafford F, Welch A, Zammit-Maempel I, Paleri V
Clin Otolaryngol 2013 Oct;38(5):372-8. doi: 10.1111/coa.12165. PMID: 23998197

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...