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Posterior uveitis

MedGen UID:
22597
•Concept ID:
C0042167
•
Disease or Syndrome
Synonyms: Posterior Uveitis; Uveitis, Posterior
SNOMED CT: Posterior uveitis (43363007)
 
HPO: HP:0012123
Monarch Initiative: MONDO:0006918

Definition

Inflammation of the uveal tract in which the primary site of inflammation is the retina or choroid. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior uveitis
Follow this link to review classifications for Posterior uveitis in Orphanet.

Conditions with this feature

Birdshot chorioretinopathy
MedGen UID:
340098
•Concept ID:
C1853959
•
Disease or Syndrome
Multiple cream-yellow colored hypopigmented lesions typically located at the level of the choroid or retinal pigment epithelium; ovoid, cream-colored with indistinct borders. They are between 50 and 1,500 micrometers in size with a characteristic nasal, radial distribution in the postequatorial fundus.
See: Condition Record
Birdshot chorioretinopathy

Professional guidelines

PubMed

Diagnosis and Treatment of Primary Inflammatory Choriocapillaropathies (PICCPs): A Comprehensive Overview.
Papasavvas I, Herbort CP Jr
Medicina (Kaunas) 2022 Jan 21;58(2) doi: 10.3390/medicina58020165. PMID: 35208488Free PMC Article
Classification Criteria for Behçet Disease Uveitis.
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:80-88. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.058. PMID: 33845008Free PMC Article
Advancements in the management of uveitis.
Schwartzman S
Best Pract Res Clin Rheumatol 2016 Apr;30(2):304-315. Epub 2016 Oct 31 doi: 10.1016/j.berh.2016.07.005. PMID: 27886802

Recent clinical studies

Etiology

Ocular Toxoplasmosis.
Goh EJH, Putera I, La Distia Nora R, Mahendradas P, Biswas J, Chee SP, Testi I, Pavesio CE, Curi ALL, Vasconcelos-Santos DV, Arora A, Gupta V, de-la-Torre A, Agrawal R
Ocul Immunol Inflamm 2023 Sep;31(7):1342-1361. Epub 2022 Sep 12 doi: 10.1080/09273948.2022.2117705. PMID: 36095008
Classification Criteria for Behçet Disease Uveitis.
Standardization of Uveitis Nomenclature (SUN) Working Group
Am J Ophthalmol 2021 Aug;228:80-88. Epub 2021 May 11 doi: 10.1016/j.ajo.2021.03.058. PMID: 33845008Free PMC Article
Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
A Focus on the Epidemiology of Uveitis.
Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, Androudi S
Ocul Immunol Inflamm 2018;26(1):2-16. Epub 2016 Jul 28 doi: 10.1080/09273948.2016.1196713. PMID: 27467180
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Diagnosis

Behçet Syndrome.
Hatemi G, Uçar D, Uygunoğlu U, Yazici H, Yazici Y
Rheum Dis Clin North Am 2023 Aug;49(3):585-602. Epub 2023 May 2 doi: 10.1016/j.rdc.2023.03.010. PMID: 37331734
Ocular toxoplasmosis: a review of the current diagnostic and therapeutic approaches.
Kalogeropoulos D, Sakkas H, Mohammed B, Vartholomatos G, Malamos K, Sreekantam S, Kanavaros P, Kalogeropoulos C
Int Ophthalmol 2022 Jan;42(1):295-321. Epub 2021 Aug 9 doi: 10.1007/s10792-021-01994-9. PMID: 34370174Free PMC Article
Vaccine-Associated Posterior Uveitis.
Cunningham ET Jr, Moorthy RS
Retin Cases Brief Rep 2022 Jan 1;16(1):1-4. doi: 10.1097/ICB.0000000000000958. PMID: 31971925
Childhood Uveitis.
Thurau S
Klin Monbl Augenheilkd 2020 Oct;237(10):1177-1186. Epub 2020 Oct 15 doi: 10.1055/a-1252-5281. PMID: 33059377
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Therapy

COVID Vaccine-Associated Uveitis.
Habot-Wilner Z, Neri P, Okada AA, Agrawal R, Xin Le N, Cohen S, Fischer N, Kilmartin F, Coman A, Kilmartin D
Ocul Immunol Inflamm 2023 Aug;31(6):1198-1205. Epub 2023 May 5 doi: 10.1080/09273948.2023.2200858. PMID: 37145198
Ocular Sarcoidosis.
Sève P, Jamilloux Y, Tilikete C, Gerfaud-Valentin M, Kodjikian L, El Jammal T
Semin Respir Crit Care Med 2020 Oct;41(5):673-688. Epub 2020 Aug 10 doi: 10.1055/s-0040-1710536. PMID: 32777852
Vaccine-Associated Posterior Uveitis.
Cunningham ET Jr, Moorthy RS
Retina 2020 Apr;40(4):595-598. doi: 10.1097/IAE.0000000000002816. PMID: 32221173
Adalimumab in Patients with Active Noninfectious Uveitis.
Jaffe GJ, Dick AD, Brézin AP, Nguyen QD, Thorne JE, Kestelyn P, Barisani-Asenbauer T, Franco P, Heiligenhaus A, Scales D, Chu DS, Camez A, Kwatra NV, Song AP, Kron M, Tari S, Suhler EB
N Engl J Med 2016 Sep 8;375(10):932-43. doi: 10.1056/NEJMoa1509852. PMID: 27602665
Posterior Uveitis.
Uy HS, Yu-Keh E, Chan PS
Dev Ophthalmol 2016;55:163-6. Epub 2015 Oct 26 doi: 10.1159/000438968. PMID: 26502276

Prognosis

Behçet Syndrome.
Hatemi G, Uçar D, Uygunoğlu U, Yazici H, Yazici Y
Rheum Dis Clin North Am 2023 Aug;49(3):585-602. Epub 2023 May 2 doi: 10.1016/j.rdc.2023.03.010. PMID: 37331734
Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
Mechanisms of macular edema: Beyond the surface.
Daruich A, Matet A, Moulin A, Kowalczuk L, Nicolas M, Sellam A, Rothschild PR, Omri S, Gélizé E, Jonet L, Delaunay K, De Kozak Y, Berdugo M, Zhao M, Crisanti P, Behar-Cohen F
Prog Retin Eye Res 2018 Mar;63:20-68. Epub 2017 Nov 7 doi: 10.1016/j.preteyeres.2017.10.006. PMID: 29126927
A Focus on the Epidemiology of Uveitis.
Tsirouki T, Dastiridou A, Symeonidis C, Tounakaki O, Brazitikou I, Kalogeropoulos C, Androudi S
Ocul Immunol Inflamm 2018;26(1):2-16. Epub 2016 Jul 28 doi: 10.1080/09273948.2016.1196713. PMID: 27467180
Viral posterior uveitis.
Lee JH, Agarwal A, Mahendradas P, Lee CS, Gupta V, Pavesio CE, Agrawal R
Surv Ophthalmol 2017 Jul-Aug;62(4):404-445. Epub 2016 Dec 22 doi: 10.1016/j.survophthal.2016.12.008. PMID: 28012878Free PMC Article

Clinical prediction guides

Retinal toxicities of systemic anticancer drugs.
Arora S, Surakiatchanukul T, Arora T, Errera MH, Agrawal H, Lupidi M, Chhablani J
Surv Ophthalmol 2022 Jan-Feb;67(1):97-148. Epub 2021 May 26 doi: 10.1016/j.survophthal.2021.05.007. PMID: 34048859
Analysis of the clinical diagnosis and treatment of uveitis.
Wang L, Guo Z, Zheng Y, Li Q, Yuan X, Hua X
Ann Palliat Med 2021 Dec;10(12):12782-12788. doi: 10.21037/apm-21-3549. PMID: 35016443
Toxoplasmosis and behavioural changes.
Desmettre T
J Fr Ophtalmol 2020 Mar;43(3):e89-e93. Epub 2020 Jan 21 doi: 10.1016/j.jfo.2020.01.001. PMID: 31980266
Punctate inner choroidopathy: A review.
Ahnood D, Madhusudhan S, Tsaloumas MD, Waheed NK, Keane PA, Denniston AK
Surv Ophthalmol 2017 Mar-Apr;62(2):113-126. Epub 2016 Oct 15 doi: 10.1016/j.survophthal.2016.10.003. PMID: 27751823
Magnetic resonance imaging of uveitis.
Li CQ, Cho AA, Edward NJ, Edward DP, Fajardo RG, Mafee MF
Neuroradiology 2015 Aug;57(8):825-32. Epub 2015 Apr 24 doi: 10.1007/s00234-015-1531-7. PMID: 25903430

Recent systematic reviews

Corticosteroid implants for chronic non-infectious uveitis.
Reddy A, Liu SH, Brady CJ, Sieving PC, Palestine AG
Cochrane Database Syst Rev 2023 Aug 29;8(8):CD010469. doi: 10.1002/14651858.CD010469.pub4. PMID: 37642198Free PMC Article
A Systematic Review of Clinical Trials in Uveitis: Lessons Learned.
Lobo-Chan AM, Joltikov K, Haseeb A, Mehta SD
Ophthalmic Epidemiol 2023 Oct;30(5):445-452. Epub 2022 Oct 6 doi: 10.1080/09286586.2022.2131837. PMID: 36204817Free PMC Article
Tubulointerstitial nephritis and uveitis syndrome: a systematic review.
Regusci A, Lava SAG, Milani GP, Bianchetti MG, Simonetti GD, Vanoni F
Nephrol Dial Transplant 2022 Apr 25;37(5):876-886. doi: 10.1093/ndt/gfab030. PMID: 33561271
Ocular Manifestations in Rheumatoid Arthritis, Connective Tissue Disease, and Vasculitis: A Systematic Review and Metaanalysis.
Turk MA, Hayworth JL, Nevskaya T, Pope JE
J Rheumatol 2021 Jan 1;48(1):25-34. Epub 2020 May 1 doi: 10.3899/jrheum.190768. PMID: 32358156
Uveitis: a global perspective.
Chang JH, Wakefield D
Ocul Immunol Inflamm 2002 Dec;10(4):263-79. doi: 10.1076/ocii.10.4.263.15592. PMID: 12854035

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