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Primary cutaneous lymphoma

MedGen UID:
220981
Concept ID:
C1302772
Neoplastic Process
Synonyms: cutaneous (skin) lymphoma; Primary Cutaneous Lymphoma; primary cutaneous lymphoma; Primary Skin Lymphoma; primary skin lymphoma
SNOMED CT: Primary cutaneous lymphoma (400001003); Primary cutaneous lymphoma (419392005)
 
Monarch Initiative: MONDO:0018898
Orphanet: ORPHA542

Definition

Cutaneous lymphoma is a heterogeneous entity with respect to its clinical and pathological features, evolutive profile, prognosis, molecular aetiology and response to therapy. These specifications have been taken into account in recent classifications, which have placed particular importance on the prognostic implications of these different entities. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPrimary cutaneous lymphoma

Professional guidelines

PubMed

D'Onghia M, Cartocci A, Calabrese L, Maio D, Sirchio A, Erasti M, Tognetti L, Rubegni P, Bocchia M, Cencini E, Fabbri A, Cinotti E
Curr Oncol 2023 Nov 8;30(11):9813-9823. doi: 10.3390/curroncol30110712. PMID: 37999132Free PMC Article
Krenitsky A, Klager S, Hatch L, Sarriera-Lazaro C, Chen PL, Seminario-Vidal L
Am J Clin Dermatol 2022 Sep;23(5):689-706. Epub 2022 Jul 19 doi: 10.1007/s40257-022-00704-0. PMID: 35854102
Pinter-Brown LC
Dermatol Clin 2015 Oct;33(4):835-40. doi: 10.1016/j.det.2015.05.003. PMID: 26433853

Curated

NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Primary Cutaneous Lymphomas, 2024

Recent clinical studies

Etiology

Zhang C, Jiang Y, Xu X, Sun J, Chen H
Dermatology 2023;239(4):553-564. Epub 2023 May 18 doi: 10.1159/000530884. PMID: 37231916
Goodlad JR, Cerroni L, Swerdlow SH
Virchows Arch 2023 Jan;482(1):281-298. Epub 2022 Oct 24 doi: 10.1007/s00428-022-03421-5. PMID: 36278991Free PMC Article
Willemze R
Presse Med 2022 Mar;51(1):104126. Epub 2022 May 13 doi: 10.1016/j.lpm.2022.104126. PMID: 35569698
Estrach T, Servitje O, Ortiz-Romero PL
Actas Dermosifiliogr 2017 Apr;108(3):181-183. doi: 10.1016/j.ad.2017.02.008. PMID: 28347423
Olek-Hrab K, Silny W, Dańczak-Pazdrowska A, Osmola-Mańkowska A, Sadowska PA, Polańska A, Gniadecki R, Jenerowicz D
Clin Exp Dermatol 2013 Mar;38(2):126-30. Epub 2012 Oct 22 doi: 10.1111/ced.12001. PMID: 23082901

Diagnosis

Olsen EA, Hodak E, Geskin L, Scarisbrick J; ISCL, USCLC, and EORTC-CLTG
J Am Acad Dermatol 2024 Feb;90(2):257-260. Epub 2023 Dec 1 doi: 10.1016/j.jaad.2023.10.007. PMID: 38043039
Goodlad JR, Cerroni L, Swerdlow SH
Virchows Arch 2023 Jan;482(1):281-298. Epub 2022 Oct 24 doi: 10.1007/s00428-022-03421-5. PMID: 36278991Free PMC Article
Olsen EA, Whittaker S, Willemze R, Pinter-Brown L, Foss F, Geskin L, Schwartz L, Horwitz S, Guitart J, Zic J, Kim YH, Wood GS, Duvic M, Ai W, Girardi M, Gru A, Guenova E, Hodak E, Hoppe R, Kempf W, Kim E, Lechowicz MJ, Ortiz-Romero P, Papadavid E, Quaglino P, Pittelkow M, Prince HM, Sanches JA, Sugaya M, Vermeer M, Zain J, Knobler R, Stadler R, Bagot M, Scarisbrick J
Blood 2022 Aug 4;140(5):419-437. doi: 10.1182/blood.2021012057. PMID: 34758074Free PMC Article
García-Herrera A, Calonje E
Surg Pathol Clin 2017 Jun;10(2):409-427. Epub 2017 Mar 28 doi: 10.1016/j.path.2017.01.003. PMID: 28477889
Jankowski M, Kopinski P, Schwartz R, Czajkowski R
Exp Dermatol 2014 Nov;23(11):792-4. doi: 10.1111/exd.12490. PMID: 25040178

Therapy

Elsayad K, Guenova E, Assaf C, Nicolay JP, Trautinger F, Stadler R, Waldstein C, Boterberg T, Meijnders P, Kirova Y, Dobos G, Duque-Santana V, Riggenbach E, Elsheshtawy W, Niezink A, Papadavid E, Scarisbrick J, Vermeer M, Neelis KJ, Bagot M, Battistella M, Quaglino P, Knobler R, Kempf W, Maklad A, Adeberg S, Kouloulias V, Simontacchi G, Corradini S, König L, Eich HT, Cowan R, Correia D
Eur J Cancer 2024 Nov;212:115064. Epub 2024 Oct 8 doi: 10.1016/j.ejca.2024.115064. PMID: 39418694
Olsen EA, Whittaker S, Willemze R, Pinter-Brown L, Foss F, Geskin L, Schwartz L, Horwitz S, Guitart J, Zic J, Kim YH, Wood GS, Duvic M, Ai W, Girardi M, Gru A, Guenova E, Hodak E, Hoppe R, Kempf W, Kim E, Lechowicz MJ, Ortiz-Romero P, Papadavid E, Quaglino P, Pittelkow M, Prince HM, Sanches JA, Sugaya M, Vermeer M, Zain J, Knobler R, Stadler R, Bagot M, Scarisbrick J
Blood 2022 Aug 4;140(5):419-437. doi: 10.1182/blood.2021012057. PMID: 34758074Free PMC Article
Enos TH, Feigenbaum LS, Wickless HW
Int J Dermatol 2017 Dec;56(12):1400-1405. Epub 2017 Aug 1 doi: 10.1111/ijd.13696. PMID: 28762479
Dabaja B
Oncol Res Treat 2017;40(5):255-260. Epub 2017 Apr 6 doi: 10.1159/000470845. PMID: 28380490
James E, Sokhn JG, Gibson JF, Carlson K, Subtil A, Girardi M, Wilson LD, Foss F
Leuk Lymphoma 2015 Apr;56(4):951-7. doi: 10.3109/10428194.2014.938331. PMID: 24996443

Prognosis

Zhang C, Jiang Y, Xu X, Sun J, Chen H
Dermatology 2023;239(4):553-564. Epub 2023 May 18 doi: 10.1159/000530884. PMID: 37231916
Olsen EA, Whittaker S, Willemze R, Pinter-Brown L, Foss F, Geskin L, Schwartz L, Horwitz S, Guitart J, Zic J, Kim YH, Wood GS, Duvic M, Ai W, Girardi M, Gru A, Guenova E, Hodak E, Hoppe R, Kempf W, Kim E, Lechowicz MJ, Ortiz-Romero P, Papadavid E, Quaglino P, Pittelkow M, Prince HM, Sanches JA, Sugaya M, Vermeer M, Zain J, Knobler R, Stadler R, Bagot M, Scarisbrick J
Blood 2022 Aug 4;140(5):419-437. doi: 10.1182/blood.2021012057. PMID: 34758074Free PMC Article
Junkins-Hopkins Md JM
Semin Diagn Pathol 2017 Jan;34(1):44-59. Epub 2016 Dec 24 doi: 10.1053/j.semdp.2016.11.004. PMID: 28187925
Olsen EA
Dermatol Clin 2015 Oct;33(4):643-54. doi: 10.1016/j.det.2015.06.001. PMID: 26433839
Jankowski M, Kopinski P, Schwartz R, Czajkowski R
Exp Dermatol 2014 Nov;23(11):792-4. doi: 10.1111/exd.12490. PMID: 25040178

Clinical prediction guides

McDonald EO, Amanullah AA, Park PSU, Song W, Werner TJ, Alavi A, Revheim ME
Ann Nucl Med 2023 Jun;37(6):328-348. Epub 2023 Apr 24 doi: 10.1007/s12149-023-01830-3. PMID: 37095393Free PMC Article
Olszewska-Szopa M, Sobas M, Laribi K, Bao Perez L, Drozd-Sokołowska J, Subocz E, Joks M, Zduniak K, Gajewska M, de Nalecz AK, Romejko-Jarosińska J, Kumiega B, Waszczuk-Gajda A, Wróbel T, Czyz A
Acta Oncol 2021 Oct;60(10):1361-1368. Epub 2021 Aug 4 doi: 10.1080/0284186X.2021.1956689. PMID: 34346830
Machan S, Juárez Martín Á, Cullen Aravena D, Haro R, Pielasinski Ú, Fuertes L, Córdoba R, Santonja C, Rodríguez-Pinilla SM, Requena L
J Cutan Pathol 2021 May;48(5):650-658. Epub 2021 Jan 13 doi: 10.1111/cup.13929. PMID: 33269496
Junkins-Hopkins Md JM
Semin Diagn Pathol 2017 Jan;34(1):44-59. Epub 2016 Dec 24 doi: 10.1053/j.semdp.2016.11.004. PMID: 28187925
Pinter-Brown LC
Dermatol Clin 2015 Oct;33(4):835-40. doi: 10.1016/j.det.2015.05.003. PMID: 26433853

Recent systematic reviews

Surmanowicz P, Doherty S, Sivanand A, Parvinnejad N, Deschenes J, Schneider M, Hardin J, Gniadecki R
Dermatology 2021;237(4):618-628. Epub 2020 Dec 16 doi: 10.1159/000511473. PMID: 33326960
Travaglino A, Varricchio S, Pace M, Russo D, Picardi M, Baldo A, Staibano S, Mascolo M
J Dtsch Dermatol Ges 2020 Dec;18(12):1379-1384. Epub 2020 Oct 8 doi: 10.1111/ddg.14289. PMID: 33029842

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Curated

    • NCCN, 2024
      NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®), Primary Cutaneous Lymphomas, 2024

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