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Refractory T-Cell Large Granular Lymphocyte Leukemia

MedGen UID:
1794066
Concept ID:
C5557625
Neoplastic Process

Definition

T-cell large granular lymphocyte leukemia that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory T-Cell Large Granular Lymphocyte Leukemia

Professional guidelines

PubMed

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T
Br J Haematol 2024 Sep;205(3):915-923. Epub 2024 Apr 19 doi: 10.1111/bjh.19476. PMID: 38639192
Zhang Y, Lee D, Gesiotto Q, Sokol L
Expert Rev Hematol 2021 Aug;14(8):731-740. Epub 2021 Jul 20 doi: 10.1080/17474086.2021.1955345. PMID: 34263714
Zhang D, Loughran TP Jr
Hematology Am Soc Hematol Educ Program 2012;2012:652-9. doi: 10.1182/asheducation-2012.1.652. PMID: 23233648

Recent clinical studies

Etiology

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T
Br J Haematol 2024 Sep;205(3):915-923. Epub 2024 Apr 19 doi: 10.1111/bjh.19476. PMID: 38639192
Braunstein Z, Mishra A, Staub A, Freud AG, Porcu P, Brammer JE
Br J Haematol 2021 Feb;192(3):484-493. Epub 2020 Jun 9 doi: 10.1111/bjh.16808. PMID: 32519348Free PMC Article
Greenberg SA, Pinkus JL, Amato AA, Kristensen T, Dorfman DM
Brain 2016 May;139(Pt 5):1348-60. Epub 2016 Feb 26 doi: 10.1093/brain/aww024. PMID: 26920676
Costa RO, Bellesso M, Chamone DA, Ruiz MA, Hallack Neto AE, Aldred VL, Pereira J
Clinics (Sao Paulo) 2012 Jul;67(7):745-8. doi: 10.6061/clinics/2012(07)07. PMID: 22892917Free PMC Article
Osuji N, Matutes E, Tjonnfjord G, Grech H, Del Giudice I, Wotherspoon A, Swansbury JG, Catovsky D
Cancer 2006 Aug 1;107(3):570-8. doi: 10.1002/cncr.22032. PMID: 16795070

Diagnosis

Zhang Y, Lee D, Gesiotto Q, Sokol L
Expert Rev Hematol 2021 Aug;14(8):731-740. Epub 2021 Jul 20 doi: 10.1080/17474086.2021.1955345. PMID: 34263714
Braunstein Z, Mishra A, Staub A, Freud AG, Porcu P, Brammer JE
Br J Haematol 2021 Feb;192(3):484-493. Epub 2020 Jun 9 doi: 10.1111/bjh.16808. PMID: 32519348Free PMC Article
Poh C, Arora M, Ghuman S, Tuscano J
Acta Haematol 2021;144(1):95-99. Epub 2020 Apr 29 doi: 10.1159/000506918. PMID: 32348994
Zhang D, Loughran TP Jr
Hematology Am Soc Hematol Educ Program 2012;2012:652-9. doi: 10.1182/asheducation-2012.1.652. PMID: 23233648
Mohan SR, Maciejewski JP
Curr Opin Hematol 2009 Jan;16(1):27-34. doi: 10.1097/MOH.0b013e32831c8407. PMID: 19057202

Therapy

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T
Br J Haematol 2024 Sep;205(3):915-923. Epub 2024 Apr 19 doi: 10.1111/bjh.19476. PMID: 38639192
Moskowitz AJ, Ghione P, Jacobsen E, Ruan J, Schatz JH, Noor S, Myskowski P, Vardhana S, Ganesan N, Hancock H, Davey T, Perez L, Ryu S, Santarosa A, Dowd J, Obadi O, Pomerantz L, Yi N, Sohail S, Galasso N, Neuman R, Liotta B, Blouin W, Baik J, Geyer MB, Noy A, Straus D, Kumar P, Dogan A, Hollmann T, Drill E, Rademaker J, Schoder H, Inghirami G, Weinstock DM, Horwitz SM
Blood 2021 Dec 30;138(26):2828-2837. doi: 10.1182/blood.2021013379. PMID: 34653242Free PMC Article
Poh C, Arora M, Ghuman S, Tuscano J
Acta Haematol 2021;144(1):95-99. Epub 2020 Apr 29 doi: 10.1159/000506918. PMID: 32348994
Zhang D, Loughran TP Jr
Hematology Am Soc Hematol Educ Program 2012;2012:652-9. doi: 10.1182/asheducation-2012.1.652. PMID: 23233648
Leblanc F, Zhang D, Liu X, Loughran TP
Future Oncol 2012 Jul;8(7):787-801. doi: 10.2217/fon.12.75. PMID: 22830400Free PMC Article

Prognosis

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T
Br J Haematol 2024 Sep;205(3):915-923. Epub 2024 Apr 19 doi: 10.1111/bjh.19476. PMID: 38639192
Zhang Y, Lee D, Gesiotto Q, Sokol L
Expert Rev Hematol 2021 Aug;14(8):731-740. Epub 2021 Jul 20 doi: 10.1080/17474086.2021.1955345. PMID: 34263714
Braunstein Z, Mishra A, Staub A, Freud AG, Porcu P, Brammer JE
Br J Haematol 2021 Feb;192(3):484-493. Epub 2020 Jun 9 doi: 10.1111/bjh.16808. PMID: 32519348Free PMC Article
Mohan SR, Maciejewski JP
Curr Opin Hematol 2009 Jan;16(1):27-34. doi: 10.1097/MOH.0b013e32831c8407. PMID: 19057202
Dearden C
Semin Oncol 2006 Apr;33(2 Suppl 5):S44-52. doi: 10.1053/j.seminoncol.2006.01.029. PMID: 16720203

Clinical prediction guides

Marchand T, Pastoret C, Damaj G, Lebouvier A, Herbaux C, Moignet A, Pavlosky M, Pavlosky A, Blouet A, Eloit M, Launay V, Lebreton P, Stamatoullas A, Nilsson C, Ochmann M, Prola J, Lamy T
Br J Haematol 2024 Sep;205(3):915-923. Epub 2024 Apr 19 doi: 10.1111/bjh.19476. PMID: 38639192
Zhu Y, Gao Q, Hu J, Liu X, Guan D, Zhang F
Leuk Res 2020 Mar;90:106299. Epub 2020 Jan 21 doi: 10.1016/j.leukres.2020.106299. PMID: 32035354
Dumitriu B, Ito S, Feng X, Stephens N, Yunce M, Kajigaya S, Melenhorst JJ, Rios O, Scheinberg P, Chinian F, Keyvanfar K, Battiwalla M, Wu CO, Maric I, Xi L, Raffeld M, Muranski P, Townsley DM, Young NS, Barrett AJ, Scheinberg P
Lancet Haematol 2016 Jan;3(1):e22-9. Epub 2015 Dec 17 doi: 10.1016/S2352-3026(15)00227-6. PMID: 26765645Free PMC Article
Shimura Y, Horiike S, Tsutsumi Y, Hatsuse M, Okano A, Fuchida S, Kobayashi T, Matsumoto Y, Kuroda J, Kawata-Iida E, Uchiyama H, Uoshima N, Shimazaki C, Kaneko H, Kobayashi Y, Taniwaki M
Int J Hematol 2015 Oct;102(4):426-33. Epub 2015 Aug 13 doi: 10.1007/s12185-015-1848-3. PMID: 26267232
Osuji N, Matutes E, Tjonnfjord G, Grech H, Del Giudice I, Wotherspoon A, Swansbury JG, Catovsky D
Cancer 2006 Aug 1;107(3):570-8. doi: 10.1002/cncr.22032. PMID: 16795070

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