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Metastatic Pancreatic Neuroendocrine Neoplasm

MedGen UID:
1715119
Concept ID:
C5237188
Neoplastic Process

Definition

A pancreatic neuroendocrine neoplasm that has spread from its original site of growth to another anatomic site. [from NCI]

Professional guidelines

PubMed

Crinò SF, Napoleon B, Facciorusso A, Lakhtakia S, Borbath I, Caillol F, Do-Cong Pham K, Rizzatti G, Forti E, Palazzo L, Belle A, Vilmann P, van Laethem JL, Mohamadnejad M, Godat S, Hindryckx P, Benson A, Tacelli M, De Nucci G, Binda C, Kovacevic B, Jacob H, Partelli S, Falconi M, Salvia R, Landoni L; ERASING study collaborators, Larghi A
Clin Gastroenterol Hepatol 2023 Oct;21(11):2834-2843.e2. Epub 2023 Mar 4 doi: 10.1016/j.cgh.2023.02.022. PMID: 36871765
Fishbein L, Del Rivero J, Else T, Howe JR, Asa SL, Cohen DL, Dahia PLM, Fraker DL, Goodman KA, Hope TA, Kunz PL, Perez K, Perrier ND, Pryma DA, Ryder M, Sasson AR, Soulen MC, Jimenez C
Pancreas 2021 Apr 1;50(4):469-493. doi: 10.1097/MPA.0000000000001792. PMID: 33939658
Weber JS, Kähler KC, Hauschild A
J Clin Oncol 2012 Jul 20;30(21):2691-7. Epub 2012 May 21 doi: 10.1200/JCO.2012.41.6750. PMID: 22614989

Recent clinical studies

Etiology

Pulvirenti A, Javed AA, Michelakos T, Sekigami Y, Zheng J, Kalvin HL, McIntyre CA, Nebbia M, Chou JF, Gonen M, Raj N, Reidy-Lagunes DL, Zureikat AH, Ferrone CR, He J, Wei AC; PAncreatic Neuroendocrine Disease Alliance (PANDA)
Ann Surg 2023 Nov 1;278(5):e1063-e1067. Epub 2023 Jan 24 doi: 10.1097/SLA.0000000000005809. PMID: 37796750Free PMC Article
Patel SP, Mayerson E, Chae YK, Strosberg J, Wang J, Konda B, Hayward J, McLeod CM, Chen HX, Sharon E, Othus M, Ryan CW, Plets M, Blanke CD, Kurzrock R
Cancer 2021 Sep 1;127(17):3194-3201. Epub 2021 Apr 21 doi: 10.1002/cncr.33591. PMID: 33882143Free PMC Article
Chin RI, Wu FS, Menda Y, Kim H
Semin Radiat Oncol 2021 Jan;31(1):60-70. doi: 10.1016/j.semradonc.2020.07.007. PMID: 33246637
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Caplin ME, Pavel M, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, Cadiot G, Wolin EM, Capdevila J, Wall L, Rindi G, Langley A, Martinez S, Blumberg J, Ruszniewski P; CLARINET Investigators
N Engl J Med 2014 Jul 17;371(3):224-33. doi: 10.1056/NEJMoa1316158. PMID: 25014687

Diagnosis

Fishbein L, Del Rivero J, Else T, Howe JR, Asa SL, Cohen DL, Dahia PLM, Fraker DL, Goodman KA, Hope TA, Kunz PL, Perez K, Perrier ND, Pryma DA, Ryder M, Sasson AR, Soulen MC, Jimenez C
Pancreas 2021 Apr 1;50(4):469-493. doi: 10.1097/MPA.0000000000001792. PMID: 33939658
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Ito T, Igarashi H, Jensen RT
J Gastroenterol 2012 Sep;47(9):941-60. Epub 2012 Aug 11 doi: 10.1007/s00535-012-0642-8. PMID: 22886480Free PMC Article

Therapy

Ambrosini V, Kunikowska J, Baudin E, Bodei L, Bouvier C, Capdevila J, Cremonesi M, de Herder WW, Dromain C, Falconi M, Fani M, Fanti S, Hicks RJ, Kabasakal L, Kaltsas G, Lewington V, Minozzi S, Cinquini M, Öberg K, Oyen WJG, O'Toole D, Pavel M, Ruszniewski P, Scarpa A, Strosberg J, Sundin A, Taïeb D, Virgolini I, Wild D, Herrmann K, Yao J
Eur J Cancer 2021 Mar;146:56-73. Epub 2021 Feb 12 doi: 10.1016/j.ejca.2021.01.008. PMID: 33588146Free PMC Article
Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Caplin ME, Pavel M, Ćwikła JB, Phan AT, Raderer M, Sedláčková E, Cadiot G, Wolin EM, Capdevila J, Wall L, Rindi G, Langley A, Martinez S, Blumberg J, Ruszniewski P; CLARINET Investigators
N Engl J Med 2014 Jul 17;371(3):224-33. doi: 10.1056/NEJMoa1316158. PMID: 25014687
Raymond E, Dahan L, Raoul JL, Bang YJ, Borbath I, Lombard-Bohas C, Valle J, Metrakos P, Smith D, Vinik A, Chen JS, Hörsch D, Hammel P, Wiedenmann B, Van Cutsem E, Patyna S, Lu DR, Blanckmeister C, Chao R, Ruszniewski P
N Engl J Med 2011 Feb 10;364(6):501-13. doi: 10.1056/NEJMoa1003825. PMID: 21306237

Prognosis

Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362
Basuroy R, Srirajaskanthan R, Ramage JK
Gastroenterol Clin North Am 2016 Sep;45(3):487-507. doi: 10.1016/j.gtc.2016.04.007. PMID: 27546845
Krampitz GW, Norton JA, Poultsides GA, Visser BC, Sun L, Jensen RT
Arch Surg 2012 Sep;147(9):820-7. doi: 10.1001/archsurg.2012.1261. PMID: 22987171Free PMC Article
Ito T, Igarashi H, Jensen RT
J Gastroenterol 2012 Sep;47(9):941-60. Epub 2012 Aug 11 doi: 10.1007/s00535-012-0642-8. PMID: 22886480Free PMC Article

Clinical prediction guides

Chin RI, Wu FS, Menda Y, Kim H
Semin Radiat Oncol 2021 Jan;31(1):60-70. doi: 10.1016/j.semradonc.2020.07.007. PMID: 33246637
Titan AL, Norton JA, Fisher AT, Foster DS, Harris EJ, Worhunsky DJ, Worth PJ, Dua MM, Visser BC, Poultsides GA, Longaker MT, Jensen RT
JAMA Netw Open 2020 Nov 2;3(11):e2024318. doi: 10.1001/jamanetworkopen.2020.24318. PMID: 33146734Free PMC Article
Perri G, Prakash LR, Katz MHG
Curr Opin Gastroenterol 2019 Sep;35(5):468-477. doi: 10.1097/MOG.0000000000000571. PMID: 31306159
Cives M, Strosberg JR
CA Cancer J Clin 2018 Nov;68(6):471-487. Epub 2018 Oct 8 doi: 10.3322/caac.21493. PMID: 30295930
Salaria SN, Shi C
Surg Pathol Clin 2016 Dec;9(4):595-617. Epub 2016 Oct 12 doi: 10.1016/j.path.2016.05.006. PMID: 27926362

Recent systematic reviews

Arman T, Nelson PS
Front Endocrinol (Lausanne) 2022;13:1012005. Epub 2022 Nov 11 doi: 10.3389/fendo.2022.1012005. PMID: 36440195Free PMC Article
Muttillo EM, Mazzarella G, Picardi B, Rossi S, Cinelli L, Diana M, Baiocchini A, Felli E, Pessaux P, Felli E, Muttillo IA
HPB (Oxford) 2022 Nov;24(11):1832-1843. Epub 2022 Jun 21 doi: 10.1016/j.hpb.2022.06.009. PMID: 35794053
Jia Z, Wang W
Eur J Radiol 2018 Mar;100:23-29. Epub 2018 Jan 9 doi: 10.1016/j.ejrad.2018.01.012. PMID: 29496075
Tamburrino D, Partelli S, Renzi C, Crippa S, Muffatti F, Perali C, Parisi A, Randolph J, Fusai GK, Cirocchi R, Falconi M
Expert Rev Gastroenterol Hepatol 2017 Jan;11(1):65-73. Epub 2016 Nov 8 doi: 10.1080/17474124.2017.1253473. PMID: 27781493
Pezzilli R, Partelli S, Cannizzaro R, Pagano N, Crippa S, Pagnanelli M, Falconi M
Adv Med Sci 2016 Mar;61(1):147-53. Epub 2015 Oct 23 doi: 10.1016/j.advms.2015.10.001. PMID: 26774266

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