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Increased circulating immature neutrophil count

MedGen UID:
1685481
Concept ID:
C5139215
Finding
HPO: HP:0032236

Definition

An abnormally increased number of immature neutrophils in the peripheral blood circulation. [from HPO]

Recent clinical studies

Etiology

Khan R, Salman S, Harford L, Sheriff L, Hazeldine J, Rajoriya N, Newsome PN, Lalor PF
Front Immunol 2024;15:1330536. Epub 2024 Mar 13 doi: 10.3389/fimmu.2024.1330536. PMID: 38545104Free PMC Article
Park J, Dean LS, Heckl J, Gangcuangco LM, Pedro TK, Tallquist MD, Seto TB, Shiramizu B, Chow DC, Shikuma CM
Sci Rep 2023 Aug 16;13(1):13282. doi: 10.1038/s41598-023-40475-0. PMID: 37587169Free PMC Article
Kong T, Lee HS, Jeon SY, You JS, Lee JW, Chung HS, Chung SP
PLoS One 2021;16(10):e0258619. Epub 2021 Oct 15 doi: 10.1371/journal.pone.0258619. PMID: 34653202Free PMC Article
Kong T, Park YS, Lee HS, Kim S, Lee JW, Yu G, Eun C, You JS, Chung HS, Park I, Chung SP
Shock 2018 Jun;49(6):649-657. doi: 10.1097/SHK.0000000000001027. PMID: 29036031
Mare TA, Treacher DF, Shankar-Hari M, Beale R, Lewis SM, Chambers DJ, Brown KA
Crit Care 2015 Feb 25;19(1):57. doi: 10.1186/s13054-015-0778-z. PMID: 25887201Free PMC Article

Diagnosis

Khan R, Salman S, Harford L, Sheriff L, Hazeldine J, Rajoriya N, Newsome PN, Lalor PF
Front Immunol 2024;15:1330536. Epub 2024 Mar 13 doi: 10.3389/fimmu.2024.1330536. PMID: 38545104Free PMC Article
Monteiro Júnior JGM, de Oliveira Cipriano Torres D, Filho DCS
Curr Cardiol Rev 2019;15(4):274-282. doi: 10.2174/1573403X15666190225123544. PMID: 30799790Free PMC Article
Kong T, Park YS, Lee HS, Kim S, Lee JW, Yu G, Eun C, You JS, Chung HS, Park I, Chung SP
Shock 2018 Jun;49(6):649-657. doi: 10.1097/SHK.0000000000001027. PMID: 29036031
Mare TA, Treacher DF, Shankar-Hari M, Beale R, Lewis SM, Chambers DJ, Brown KA
Crit Care 2015 Feb 25;19(1):57. doi: 10.1186/s13054-015-0778-z. PMID: 25887201Free PMC Article
Verschoor CP, Loukov D, Naidoo A, Puchta A, Johnstone J, Millar J, Lelic A, Novakowski KE, Dorrington MG, Loeb M, Bramson JL, Bowdish DM
Mol Immunol 2015 May;65(1):148-56. Epub 2015 Feb 5 doi: 10.1016/j.molimm.2015.01.015. PMID: 25660689

Therapy

Ferreira-Duarte AP, Pinheiro-Torres AS, Takeshita WM, Gushiken VO, Roncalho-Buck IA, Anhê GF, DeSouza IA
Int Immunopharmacol 2020 Jan;78:106009. Epub 2019 Nov 23 doi: 10.1016/j.intimp.2019.106009. PMID: 31771815
Kumagai Y, Ohzawa H, Miyato H, Horie H, Hosoya Y, Lefor AK, Sata N, Kitayama J
J Surg Res 2020 Feb;246:52-61. Epub 2019 Sep 24 doi: 10.1016/j.jss.2019.08.022. PMID: 31561178
Yin J, Wang C, Huang M, Mao X, Zhou J, Zhang Y
Cancer Med 2016 Jul;5(7):1654-69. Epub 2016 Apr 25 doi: 10.1002/cam4.688. PMID: 27109254Free PMC Article
Baley JE, Stork EK, Warkentin PI, Shurin SB
Pediatrics 1987 Nov;80(5):712-20. PMID: 3670972
Hetherington SV, Quie PG
Am J Hematol 1985 Nov;20(3):235-46. doi: 10.1002/ajh.2830200305. PMID: 2998184

Prognosis

Khan R, Salman S, Harford L, Sheriff L, Hazeldine J, Rajoriya N, Newsome PN, Lalor PF
Front Immunol 2024;15:1330536. Epub 2024 Mar 13 doi: 10.3389/fimmu.2024.1330536. PMID: 38545104Free PMC Article
Schnegg-Kaufmann AS, Thoms JAI, Bhuyan GS, Hampton HR, Vaughan L, Rutherford K, Kakadia PM, Lee HM, Johansson EMV, Failes TW, Arndt GM, Koval J, Lindeman R, Warburton P, Rodriguez-Meira A, Mead AJ, Unnikrishnan A, Davidson S, Polizzotto MN, Hertzberg M, Papaemmanuil E, Bohlander SK, Faridani OR, Jolly CJ, Zanini F, Pimanda JE
Blood 2023 Mar 16;141(11):1316-1321. doi: 10.1182/blood.2022018602. PMID: 36493342Free PMC Article
Lee JY, Han BG, Choi SO, Eom M, Kim SH, Kim JS, Yang JW
Transplant Proc 2019 Oct;51(8):2671-2675. Epub 2019 Aug 30 doi: 10.1016/j.transproceed.2019.03.083. PMID: 31477419
Monteiro Júnior JGM, de Oliveira Cipriano Torres D, Filho DCS
Curr Cardiol Rev 2019;15(4):274-282. doi: 10.2174/1573403X15666190225123544. PMID: 30799790Free PMC Article
Kong T, Park YS, Lee HS, Kim S, Lee JW, Yu G, Eun C, You JS, Chung HS, Park I, Chung SP
Shock 2018 Jun;49(6):649-657. doi: 10.1097/SHK.0000000000001027. PMID: 29036031

Clinical prediction guides

Khan R, Salman S, Harford L, Sheriff L, Hazeldine J, Rajoriya N, Newsome PN, Lalor PF
Front Immunol 2024;15:1330536. Epub 2024 Mar 13 doi: 10.3389/fimmu.2024.1330536. PMID: 38545104Free PMC Article
Lourda M, Dzidic M, Hertwig L, Bergsten H, Palma Medina LM, Sinha I, Kvedaraite E, Chen P, Muvva JR, Gorin JB, Cornillet M, Emgård J, Moll K, García M, Maleki KT, Klingström J, Michaëlsson J, Flodström-Tullberg M, Brighenti S, Buggert M, Mjösberg J, Malmberg KJ, Sandberg JK, Henter JI, Folkesson E, Gredmark-Russ S, Sönnerborg A, Eriksson LI, Rooyackers O, Aleman S, Strålin K, Ljunggren HG, Björkström NK, Svensson M, Ponzetta A, Norrby-Teglund A, Chambers BJ; Karolinska KI/K COVID-19 Study Group
Proc Natl Acad Sci U S A 2021 Oct 5;118(40) doi: 10.1073/pnas.2109123118. PMID: 34548411Free PMC Article
Monteiro Júnior JGM, de Oliveira Cipriano Torres D, Filho DCS
Curr Cardiol Rev 2019;15(4):274-282. doi: 10.2174/1573403X15666190225123544. PMID: 30799790Free PMC Article
Duggal NA, Snelson C, Shaheen U, Pearce V, Lord JM
Sci Rep 2018 Jul 5;8(1):10186. doi: 10.1038/s41598-018-28409-7. PMID: 29976949Free PMC Article
Taneja R, Sharma AP, Hallett MB, Findlay GP, Morris MR
Shock 2008 Dec;30(6):618-22. doi: 10.1097/SHK.0b013e318173ef9c. PMID: 18496237

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