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Refractory Myelodysplastic Syndrome

MedGen UID:
1656162
Concept ID:
C4724986
Neoplastic Process

Definition

Myelodysplastic syndrome that does not respond to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Myelodysplastic Syndrome

Professional guidelines

PubMed

Garcia-Manero G
Am J Hematol 2023 Aug;98(8):1307-1325. Epub 2023 Jun 8 doi: 10.1002/ajh.26984. PMID: 37288607
Duffy MJ, O'Grady S, Tang M, Crown J
Cancer Treat Rev 2021 Mar;94:102154. Epub 2021 Jan 19 doi: 10.1016/j.ctrv.2021.102154. PMID: 33524794
Ullmann AJ, Aguado JM, Arikan-Akdagli S, Denning DW, Groll AH, Lagrou K, Lass-Flörl C, Lewis RE, Munoz P, Verweij PE, Warris A, Ader F, Akova M, Arendrup MC, Barnes RA, Beigelman-Aubry C, Blot S, Bouza E, Brüggemann RJM, Buchheidt D, Cadranel J, Castagnola E, Chakrabarti A, Cuenca-Estrella M, Dimopoulos G, Fortun J, Gangneux JP, Garbino J, Heinz WJ, Herbrecht R, Heussel CP, Kibbler CC, Klimko N, Kullberg BJ, Lange C, Lehrnbecher T, Löffler J, Lortholary O, Maertens J, Marchetti O, Meis JF, Pagano L, Ribaud P, Richardson M, Roilides E, Ruhnke M, Sanguinetti M, Sheppard DC, Sinkó J, Skiada A, Vehreschild MJGT, Viscoli C, Cornely OA
Clin Microbiol Infect 2018 May;24 Suppl 1:e1-e38. Epub 2018 Mar 12 doi: 10.1016/j.cmi.2018.01.002. PMID: 29544767

Recent clinical studies

Etiology

Connor MP, Loren AW, Hexner EO, Martin ME, Gill SI, Luger SM, Mangan JK, Perl AE, McCurdy SR, Pratz KW, Timlin C, Freyer CW, Carulli A, Catania C, Smith J, Hollander L, Zebrowski AM, Stadtmauer EA, Porter DL, Frey NV
Transplant Cell Ther 2023 Feb;29(2):113-118. Epub 2022 Nov 4 doi: 10.1016/j.jtct.2022.10.027. PMID: 36336258

Diagnosis

Srisuttiyakorn C, Reeve J, Reddy S, Imaeda S, Lazova R
J Cutan Pathol 2014 May;41(5):475-9. doi: 10.1111/cup.12305. PMID: 24877196

Therapy

DiNardo CD, Roboz GJ, Watts JM, Madanat YF, Prince GT, Baratam P, de Botton S, Stein A, Foran JM, Arellano ML, Sallman DA, Hossain M, Marchione DM, Bai X, Patel PA, Kapsalis SM, Garcia-Manero G, Fathi AT
Blood Adv 2024 Aug 13;8(15):4209-4220. doi: 10.1182/bloodadvances.2023012302. PMID: 38640348Free PMC Article
Dawson MA, Borthakur G, Huntly BJP, Karadimitris A, Alegre A, Chaidos A, Vogl DT, Pollyea DA, Davies FE, Morgan GJ, Glass JL, Kamdar M, Mateos MV, Tovar N, Yeh P, Delgado RG, Basheer F, Marando L, Gallipoli P, Wyce A, Krishnatry AS, Barbash O, Bakirtzi E, Ferron-Brady G, Karpinich NO, McCabe MT, Foley SW, Horner T, Dhar A, Kremer BE, Dickinson M
Clin Cancer Res 2023 Feb 16;29(4):711-722. doi: 10.1158/1078-0432.CCR-22-1284. PMID: 36350312Free PMC Article
Connor MP, Loren AW, Hexner EO, Martin ME, Gill SI, Luger SM, Mangan JK, Perl AE, McCurdy SR, Pratz KW, Timlin C, Freyer CW, Carulli A, Catania C, Smith J, Hollander L, Zebrowski AM, Stadtmauer EA, Porter DL, Frey NV
Transplant Cell Ther 2023 Feb;29(2):113-118. Epub 2022 Nov 4 doi: 10.1016/j.jtct.2022.10.027. PMID: 36336258
Roboz GJ, Desai P, Lee S, Ritchie EK, Winer ES, DeMario M, Brennan B, Nüesch E, Chesne E, Brennan L, Lechner K, Kornacker M, DeAngelo DJ
Leuk Lymphoma 2021 Jul;62(7):1740-1748. Epub 2021 Feb 13 doi: 10.1080/10428194.2021.1881509. PMID: 33586590
Hassaballa HA, Lateef OB, Silver MR, Balk RA
J Crit Care 2005 Mar;20(1):111-3. doi: 10.1016/j.jcrc.2004.08.009. PMID: 16015525

Prognosis

Connor MP, Loren AW, Hexner EO, Martin ME, Gill SI, Luger SM, Mangan JK, Perl AE, McCurdy SR, Pratz KW, Timlin C, Freyer CW, Carulli A, Catania C, Smith J, Hollander L, Zebrowski AM, Stadtmauer EA, Porter DL, Frey NV
Transplant Cell Ther 2023 Feb;29(2):113-118. Epub 2022 Nov 4 doi: 10.1016/j.jtct.2022.10.027. PMID: 36336258
Cherian MA, Tibes R, Gao F, Fletcher T, Fiala M, Uy GL, Westervelt P, Jacoby MA, Cashen AF, Stockerl-Goldstein K, DiPersio JF, Vij R
Leuk Lymphoma 2016 Nov;57(11):2535-40. Epub 2016 Apr 27 doi: 10.3109/10428194.2016.1173213. PMID: 27122296

Clinical prediction guides

DiNardo CD, Roboz GJ, Watts JM, Madanat YF, Prince GT, Baratam P, de Botton S, Stein A, Foran JM, Arellano ML, Sallman DA, Hossain M, Marchione DM, Bai X, Patel PA, Kapsalis SM, Garcia-Manero G, Fathi AT
Blood Adv 2024 Aug 13;8(15):4209-4220. doi: 10.1182/bloodadvances.2023012302. PMID: 38640348Free PMC Article
Dawson MA, Borthakur G, Huntly BJP, Karadimitris A, Alegre A, Chaidos A, Vogl DT, Pollyea DA, Davies FE, Morgan GJ, Glass JL, Kamdar M, Mateos MV, Tovar N, Yeh P, Delgado RG, Basheer F, Marando L, Gallipoli P, Wyce A, Krishnatry AS, Barbash O, Bakirtzi E, Ferron-Brady G, Karpinich NO, McCabe MT, Foley SW, Horner T, Dhar A, Kremer BE, Dickinson M
Clin Cancer Res 2023 Feb 16;29(4):711-722. doi: 10.1158/1078-0432.CCR-22-1284. PMID: 36350312Free PMC Article

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