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Advanced Bile Duct Carcinoma

MedGen UID:
1647986
•Concept ID:
C4684880
•
Neoplastic Process
Synonyms: Advanced Bile Duct Cancer; Advanced Biliary Tract Cancer; Advanced Biliary Tract Carcinoma

Definition

A carcinoma that arises from the intrahepatic or extrahepatic bile ducts and has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Professional guidelines

PubMed

Synergic effect of photodynamic therapy using talaporfin sodium with conventional anticancer chemotherapy for the treatment of bile duct carcinoma.
Nonaka Y, Nanashima A, Nonaka T, Uehara M, Isomoto H, Abo T, Nagayasu T
J Surg Res 2013 May;181(2):234-41. Epub 2012 Jul 13 doi: 10.1016/j.jss.2012.06.047. PMID: 22835954
Intracatheter hyperthermia and iridium-192 radiotherapy in the treatment of bile duct carcinoma.
Wong JY, Vora NL, Chou CK, McDougall JA, Chan KW, Findley DO, Forell BW, Luk KH, Philben VJ, Beatty JD
Int J Radiat Oncol Biol Phys 1988 Feb;14(2):353-9. doi: 10.1016/0360-3016(88)90443-9. PMID: 3338957

Recent clinical studies

Etiology

Photodynamic Therapy Using Novel Glucose-conjugated Chlorin Increases Apoptosis of Cholangiocellular Carcinoma in Comparison with Talaporfin Sodium.
Murakami G, Nanashima A, Nonaka T, Tominaga T, Wakata K, Sumida Y, Akashi H, Okazaki S, Kataoka H, Nagayasu T
Anticancer Res 2016 Sep;36(9):4493-501. doi: 10.21873/anticanres.10995. PMID: 27630287
Major hepatectomy and pancreatoduodenectomy for advanced carcinoma of the biliary tract.
Tsukada K, Yoshida K, Aono T, Koyama S, Shirai Y, Uchida K, Muto T
Br J Surg 1994 Jan;81(1):108-10. doi: 10.1002/bjs.1800810139. PMID: 7906181
Hazard and outcome of retreated choledochal cyst patients.
Chijiiwa K
Int Surg 1993 Jul-Sep;78(3):204-7. PMID: 8276541
Intraoperative radiation therapy for biliary tract carcinoma: results of a 5-year experience.
Busse PM, Stone MD, Sheldon TA, Chaffey JT, Cady B, McDermott WV, Bothe A Jr, Jenkins R, Steele G Jr
Surgery 1989 Jun;105(6):724-33. PMID: 2727900
Eastern Cooperative Oncology Group experience with chemotherapy for inoperable gallbladder and bile duct cancer.
Falkson G, MacIntyre JM, Moertel CG
Cancer 1984 Sep 15;54(6):965-9. doi: 10.1002/1097-0142(19840915)54:6<965::aid-cncr2820540603>3.0.co;2-x. PMID: 6235908

Diagnosis

A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.
Takayoshi K, Sagara K, Uchino K, Kusaba H, Sakamoto N, Iguchi A, Baba E
BMC Cancer 2015 May 22;15:426. doi: 10.1186/s12885-015-1443-2. PMID: 26001650Free PMC Article

Therapy

Two cases of bile duct carcinoma patients who underwent the photodynamic therapy using talaporfin sodium (Laserphyrin(®)).
Nanashima A, Hiyoshi M, Imamura N, Hamada T, Nishida T, Kawakami H, Ban T, Kubota Y, Nakashima K, Yano K, Wada T, Takeno S, Kai M
Clin J Gastroenterol 2020 Feb;13(1):102-109. Epub 2019 Jun 20 doi: 10.1007/s12328-019-01006-5. PMID: 31222455
A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.
Takayoshi K, Sagara K, Uchino K, Kusaba H, Sakamoto N, Iguchi A, Baba E
BMC Cancer 2015 May 22;15:426. doi: 10.1186/s12885-015-1443-2. PMID: 26001650Free PMC Article
Synergic effect of photodynamic therapy using talaporfin sodium with conventional anticancer chemotherapy for the treatment of bile duct carcinoma.
Nonaka Y, Nanashima A, Nonaka T, Uehara M, Isomoto H, Abo T, Nagayasu T
J Surg Res 2013 May;181(2):234-41. Epub 2012 Jul 13 doi: 10.1016/j.jss.2012.06.047. PMID: 22835954
Thermo-chemo-radiotherapy for advanced bile duct carcinoma.
Kamisawa T, Tu Y, Egawa N, Karasawa K, Matsuda T, Tsuruta K, Okamoto A
World J Gastroenterol 2005 Jul 21;11(27):4206-9. doi: 10.3748/wjg.v11.i27.4206. PMID: 16015690Free PMC Article
Intracatheter hyperthermia and iridium-192 radiotherapy in the treatment of bile duct carcinoma.
Wong JY, Vora NL, Chou CK, McDougall JA, Chan KW, Findley DO, Forell BW, Luk KH, Philben VJ, Beatty JD
Int J Radiat Oncol Biol Phys 1988 Feb;14(2):353-9. doi: 10.1016/0360-3016(88)90443-9. PMID: 3338957

Prognosis

A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.
Takayoshi K, Sagara K, Uchino K, Kusaba H, Sakamoto N, Iguchi A, Baba E
BMC Cancer 2015 May 22;15:426. doi: 10.1186/s12885-015-1443-2. PMID: 26001650Free PMC Article
Thermo-chemo-radiotherapy for advanced bile duct carcinoma.
Kamisawa T, Tu Y, Egawa N, Karasawa K, Matsuda T, Tsuruta K, Okamoto A
World J Gastroenterol 2005 Jul 21;11(27):4206-9. doi: 10.3748/wjg.v11.i27.4206. PMID: 16015690Free PMC Article
Major hepatectomy and pancreatoduodenectomy for advanced carcinoma of the biliary tract.
Tsukada K, Yoshida K, Aono T, Koyama S, Shirai Y, Uchida K, Muto T
Br J Surg 1994 Jan;81(1):108-10. doi: 10.1002/bjs.1800810139. PMID: 7906181
Hazard and outcome of retreated choledochal cyst patients.
Chijiiwa K
Int Surg 1993 Jul-Sep;78(3):204-7. PMID: 8276541
Intraoperative radiation therapy for biliary tract carcinoma: results of a 5-year experience.
Busse PM, Stone MD, Sheldon TA, Chaffey JT, Cady B, McDermott WV, Bothe A Jr, Jenkins R, Steele G Jr
Surgery 1989 Jun;105(6):724-33. PMID: 2727900

Clinical prediction guides

Two cases of bile duct carcinoma patients who underwent the photodynamic therapy using talaporfin sodium (Laserphyrin(®)).
Nanashima A, Hiyoshi M, Imamura N, Hamada T, Nishida T, Kawakami H, Ban T, Kubota Y, Nakashima K, Yano K, Wada T, Takeno S, Kai M
Clin J Gastroenterol 2020 Feb;13(1):102-109. Epub 2019 Jun 20 doi: 10.1007/s12328-019-01006-5. PMID: 31222455
A case of metastatic renal cell carcinoma and bile duct carcinoma treated with a combination of sunitinib and gemcitabine.
Takayoshi K, Sagara K, Uchino K, Kusaba H, Sakamoto N, Iguchi A, Baba E
BMC Cancer 2015 May 22;15:426. doi: 10.1186/s12885-015-1443-2. PMID: 26001650Free PMC Article
Thermo-chemo-radiotherapy for advanced bile duct carcinoma.
Kamisawa T, Tu Y, Egawa N, Karasawa K, Matsuda T, Tsuruta K, Okamoto A
World J Gastroenterol 2005 Jul 21;11(27):4206-9. doi: 10.3748/wjg.v11.i27.4206. PMID: 16015690Free PMC Article

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