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Refractory Lung Carcinoma

MedGen UID:
1639600
Concept ID:
C4683497
Neoplastic Process

Definition

Lung carcinoma that does not respond to treatment. [from NCI]

Professional guidelines

PubMed

Yu Y, Chen K, Fan Y
Int J Cancer 2023 Jun 1;152(11):2243-2256. Epub 2022 Nov 29 doi: 10.1002/ijc.34346. PMID: 36346100
Wang S, Zimmermann S, Parikh K, Mansfield AS, Adjei AA
Mayo Clin Proc 2019 Aug;94(8):1599-1622. doi: 10.1016/j.mayocp.2019.01.034. PMID: 31378235
Champiat S, Lambotte O, Barreau E, Belkhir R, Berdelou A, Carbonnel F, Cauquil C, Chanson P, Collins M, Durrbach A, Ederhy S, Feuillet S, François H, Lazarovici J, Le Pavec J, De Martin E, Mateus C, Michot JM, Samuel D, Soria JC, Robert C, Eggermont A, Marabelle A
Ann Oncol 2016 Apr;27(4):559-74. Epub 2015 Dec 28 doi: 10.1093/annonc/mdv623. PMID: 26715621

Recent clinical studies

Etiology

Dicpinigaitis PV, Morice AH, Smith JA, Sher MR, Vaezi M, Guilleminault L, Niimi A, Gude K, Krahn U, Saarinen R, Pires PV, Wosnitza M, McGarvey L; PAGANINI Investigators
Lung 2023 Jun;201(3):255-266. Epub 2023 Jun 1 doi: 10.1007/s00408-023-00621-x. PMID: 37261531Free PMC Article
Li BT, Smit EF, Goto Y, Nakagawa K, Udagawa H, Mazières J, Nagasaka M, Bazhenova L, Saltos AN, Felip E, Pacheco JM, Pérol M, Paz-Ares L, Saxena K, Shiga R, Cheng Y, Acharyya S, Vitazka P, Shahidi J, Planchard D, Jänne PA; DESTINY-Lung01 Trial Investigators
N Engl J Med 2022 Jan 20;386(3):241-251. Epub 2021 Sep 18 doi: 10.1056/NEJMoa2112431. PMID: 34534430Free PMC Article
Wang S, Zimmermann S, Parikh K, Mansfield AS, Adjei AA
Mayo Clin Proc 2019 Aug;94(8):1599-1622. doi: 10.1016/j.mayocp.2019.01.034. PMID: 31378235
Suresh K, Naidoo J, Lin CT, Danoff S
Chest 2018 Dec;154(6):1416-1423. Epub 2018 Sep 4 doi: 10.1016/j.chest.2018.08.1048. PMID: 30189190Free PMC Article
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article

Diagnosis

Larrue R, Fellah S, Boukrout N, De Sousa C, Lemaire J, Leboeuf C, Goujon M, Perrais M, Mari B, Cauffiez C, Pottier N, Van der Hauwaert C
Cell Death Dis 2023 Sep 13;14(9):603. doi: 10.1038/s41419-023-06125-z. PMID: 37704611Free PMC Article
Wong SK, Horn L
Cancer J 2020 Nov/Dec;26(6):496-501. doi: 10.1097/PPO.0000000000000482. PMID: 33298720
Owen DH, Giffin MJ, Bailis JM, Smit MD, Carbone DP, He K
J Hematol Oncol 2019 Jun 18;12(1):61. doi: 10.1186/s13045-019-0745-2. PMID: 31215500Free PMC Article
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Lee WR, Giantonio B, Hanks GE
Curr Probl Cancer 1994 Nov-Dec;18(6):295-357. doi: 10.1016/0147-0272(94)90005-1. PMID: 7536141

Therapy

Larrue R, Fellah S, Boukrout N, De Sousa C, Lemaire J, Leboeuf C, Goujon M, Perrais M, Mari B, Cauffiez C, Pottier N, Van der Hauwaert C
Cell Death Dis 2023 Sep 13;14(9):603. doi: 10.1038/s41419-023-06125-z. PMID: 37704611Free PMC Article
Markham A
Drugs 2021 Nov;81(17):2063-2068. doi: 10.1007/s40265-021-01628-5. PMID: 34709602
Markham A, Keam SJ
Drugs 2019 Aug;79(12):1355-1361. doi: 10.1007/s40265-019-01167-0. PMID: 31313098
Zhao Q, Yu J, Meng X
Cancer Med 2019 Aug;8(10):4519-4526. Epub 2019 Jun 23 doi: 10.1002/cam4.2336. PMID: 31231980Free PMC Article
Dhillon S
Drugs 2019 Feb;79(3):331-339. doi: 10.1007/s40265-019-1062-3. PMID: 30721452

Prognosis

Larrue R, Fellah S, Boukrout N, De Sousa C, Lemaire J, Leboeuf C, Goujon M, Perrais M, Mari B, Cauffiez C, Pottier N, Van der Hauwaert C
Cell Death Dis 2023 Sep 13;14(9):603. doi: 10.1038/s41419-023-06125-z. PMID: 37704611Free PMC Article
Li BT, Smit EF, Goto Y, Nakagawa K, Udagawa H, Mazières J, Nagasaka M, Bazhenova L, Saltos AN, Felip E, Pacheco JM, Pérol M, Paz-Ares L, Saxena K, Shiga R, Cheng Y, Acharyya S, Vitazka P, Shahidi J, Planchard D, Jänne PA; DESTINY-Lung01 Trial Investigators
N Engl J Med 2022 Jan 20;386(3):241-251. Epub 2021 Sep 18 doi: 10.1056/NEJMoa2112431. PMID: 34534430Free PMC Article
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Rowe J, Cen P
Hum Vaccin Immunother 2014;10(11):3196-200. doi: 10.4161/21645515.2014.973323. PMID: 25483641Free PMC Article
Lee WR, Giantonio B, Hanks GE
Curr Probl Cancer 1994 Nov-Dec;18(6):295-357. doi: 10.1016/0147-0272(94)90005-1. PMID: 7536141

Clinical prediction guides

Hallin J, Engstrom LD, Hargis L, Calinisan A, Aranda R, Briere DM, Sudhakar N, Bowcut V, Baer BR, Ballard JA, Burkard MR, Fell JB, Fischer JP, Vigers GP, Xue Y, Gatto S, Fernandez-Banet J, Pavlicek A, Velastagui K, Chao RC, Barton J, Pierobon M, Baldelli E, Patricoin EF 3rd, Cassidy DP, Marx MA, Rybkin II, Johnson ML, Ou SI, Lito P, Papadopoulos KP, Jänne PA, Olson P, Christensen JG
Cancer Discov 2020 Jan;10(1):54-71. Epub 2019 Oct 28 doi: 10.1158/2159-8290.CD-19-1167. PMID: 31658955Free PMC Article
Zhang M, Yang J, Hua W, Li Z, Xu Z, Qian Q
Front Med 2019 Feb;13(1):32-44. Epub 2019 Jan 24 doi: 10.1007/s11684-018-0678-0. PMID: 30680606
Hsieh JJ, Purdue MP, Signoretti S, Swanton C, Albiges L, Schmidinger M, Heng DY, Larkin J, Ficarra V
Nat Rev Dis Primers 2017 Mar 9;3:17009. doi: 10.1038/nrdp.2017.9. PMID: 28276433Free PMC Article
Rowe J, Cen P
Hum Vaccin Immunother 2014;10(11):3196-200. doi: 10.4161/21645515.2014.973323. PMID: 25483641Free PMC Article
Lee WR, Giantonio B, Hanks GE
Curr Probl Cancer 1994 Nov-Dec;18(6):295-357. doi: 10.1016/0147-0272(94)90005-1. PMID: 7536141

Recent systematic reviews

Zhao Y, He Y, Wang W, Cai Q, Ge F, Chen Z, Zheng J, Zhang Y, Deng H, Chen Y, Lao S, Liang H, Liang W, He J
Lancet Oncol 2024 Oct;25(10):1347-1356. Epub 2024 Aug 16 doi: 10.1016/S1470-2045(24)00379-6. PMID: 39159630
Jiménez-Labaig P, Rullan A, Hernando-Calvo A, Llop S, Bhide S, O'Leary B, Braña I, Harrington KJ
Cancer Treat Rev 2024 Jul;128:102772. Epub 2024 May 26 doi: 10.1016/j.ctrv.2024.102772. PMID: 38820656
Häuser W, Welsch P, Radbruch L, Fisher E, Bell RF, Moore RA
Cochrane Database Syst Rev 2023 Jun 5;6(6):CD014915. doi: 10.1002/14651858.CD014915.pub2. PMID: 37283486Free PMC Article
Parisi C, Mahjoubi L, Gazzah A, Barlesi F
Cancer Treat Rev 2023 Jul;118:102572. Epub 2023 May 19 doi: 10.1016/j.ctrv.2023.102572. PMID: 37230055
Dogan V, Rieckmann T, Münscher A, Busch CJ
Clin Otolaryngol 2018 Feb;43(1):13-21. Epub 2017 May 29 doi: 10.1111/coa.12895. PMID: 28464441

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