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Disorder of pharynx

MedGen UID:
10691
•Concept ID:
C0031345
•
Disease or Syndrome
Synonym: Disease of pharynx
SNOMED CT: Disorder of pharynx (75860007)
 
Monarch Initiative: MONDO:0020592

Definition

A non-neoplastic or neoplastic disorder that affects the pharynx. Representative examples include pharyngitis and carcinoma. [from NCI]

Professional guidelines

PubMed

HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management.
Lechner M, Liu J, Masterson L, Fenton TR
Nat Rev Clin Oncol 2022 May;19(5):306-327. Epub 2022 Feb 1 doi: 10.1038/s41571-022-00603-7. PMID: 35105976Free PMC Article
Pharyngitis: Approach to diagnosis and treatment.
Sykes EA, Wu V, Beyea MM, Simpson MTW, Beyea JA
Can Fam Physician 2020 Apr;66(4):251-257. PMID: 32273409Free PMC Article
Clinical Practice Guideline: Tonsillectomy in Children (Update)-Executive Summary.
Mitchell RB, Archer SM, Ishman SL, Rosenfeld RM, Coles S, Finestone SA, Friedman NR, Giordano T, Hildrew DM, Kim TW, Lloyd RM, Parikh SR, Shulman ST, Walner DL, Walsh SA, Nnacheta LC
Otolaryngol Head Neck Surg 2019 Feb;160(2):187-205. doi: 10.1177/0194599818807917. PMID: 30921525

Recent clinical studies

Etiology

Risk factor of pharyngocutaneous fistula.
Kedous S, Turki S, Elhedhili F, Dhambri S, Jbeli S, Touati S, Gritli S
Tunis Med 2019 Mar;97(3):491-499. PMID: 31729725
Reconstruction after salvage laryngectomy.
Yeh DH, Sahovaler A, Fung K
Oral Oncol 2017 Dec;75:22-27. Epub 2017 Oct 21 doi: 10.1016/j.oraloncology.2017.10.009. PMID: 29224818
Deep neck infections.
Conrad DE, Parikh SR
Infect Disord Drug Targets 2012 Aug;12(4):286-90. doi: 10.2174/187152612801319348. PMID: 22338590
Pharyngocutaneous fistula.
Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083
Discoordinate pharyngolaryngomalacia.
Froehlich P, Seid AB, Denoyelle F, Pransky SM, Kearns DB, Garabedian EN, Morgon A
Int J Pediatr Otorhinolaryngol 1997 Feb 14;39(1):9-18. doi: 10.1016/S0165-5876(96)01454-1. PMID: 9051435

Diagnosis

Pharyngeal rhinosporidiosis.
Chandran A, Sakthivel P, Kumar R, Rajeshwari M
BMJ Case Rep 2020 Jun 17;13(6) doi: 10.1136/bcr-2020-236404. PMID: 32554456Free PMC Article
Glossopharyngeal neuralgia.
Blumenfeld A, Nikolskaya G
Curr Pain Headache Rep 2013 Jul;17(7):343. doi: 10.1007/s11916-013-0343-x. PMID: 23709235
Laryngopharyngeal reflux.
Franco RA Jr
Allergy Asthma Proc 2006 Jan-Feb;27(1):21-5. PMID: 16598989
Pharyngocutaneous fistula.
Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083
Throat disorders.
Berger MS
Prim Care 1998 Sep;25(3):685-99. doi: 10.1016/s0095-4543(15)30009-9. PMID: 9673327

Therapy

Role of Exosomes in Pharyngucutaneous Fistula After Total Laryngectomy.
Chen L, Wang M, Zhong Z, Liu B, Zhang W, Zhu B, Jiao C, Yu C, Guan B
Int J Nanomedicine 2022;17:4119-4135. Epub 2022 Sep 12 doi: 10.2147/IJN.S372042. PMID: 36118178Free PMC Article
Role of steroids in conservative treatment of parapharyngeal and retropharyngeal abscess in children.
Villanueva-Fernández E, Casanueva-Muruáis R, Vivanco-Allende A, Llorente JL, Coca-Pelaz A
Eur Arch Otorhinolaryngol 2022 Nov;279(11):5331-5338. Epub 2022 Jun 29 doi: 10.1007/s00405-022-07423-6. PMID: 35767057Free PMC Article
Management of isolated cricopharyngeal dysfunction: systematic review.
Ashman A, Dale OT, Baldwin DL
J Laryngol Otol 2016 Jul;130(7):611-5. Epub 2016 May 19 doi: 10.1017/S0022215116007994. PMID: 27194375
Oropharyngeal histoplasmosis: report of eleven cases and review of the literature.
Antonello VS, Zaltron VF, Vial M, Oliveira FM, Severo LC
Rev Soc Bras Med Trop 2011 Jan-Feb;44(1):26-9. doi: 10.1590/s0037-86822011000100007. PMID: 21340403
Retropharyngeal abscess.
Hamer R
Ann Emerg Med 1982 Oct;11(10):549-52. doi: 10.1016/s0196-0644(82)80429-0. PMID: 7125316

Prognosis

Risk factor of pharyngocutaneous fistula.
Kedous S, Turki S, Elhedhili F, Dhambri S, Jbeli S, Touati S, Gritli S
Tunis Med 2019 Mar;97(3):491-499. PMID: 31729725
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
Second branchial cleft anomalies in children: a literature review.
Shen LF, Zhou SH, Chen QQ, Yu Q
Pediatr Surg Int 2018 Dec;34(12):1251-1256. Epub 2018 Sep 24 doi: 10.1007/s00383-018-4348-8. PMID: 30251021
Congenital lesions of epithelial origin.
Hills SE, Maddalozzo J
Otolaryngol Clin North Am 2015 Feb;48(1):209-23. doi: 10.1016/j.otc.2014.09.014. PMID: 25439555
Pharyngocutaneous fistula.
Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083

Clinical prediction guides

Risk factor of pharyngocutaneous fistula.
Kedous S, Turki S, Elhedhili F, Dhambri S, Jbeli S, Touati S, Gritli S
Tunis Med 2019 Mar;97(3):491-499. PMID: 31729725
Elucidating inconsistencies in dysphagia diagnostics: Redefining normal.
Plowman EK, Humbert IA
Int J Speech Lang Pathol 2018 Jun;20(3):310-317. Epub 2018 May 3 doi: 10.1080/17549507.2018.1461931. PMID: 29724130
The Toronto Bedside Swallowing Screening Test (TOR-BSST): development and validation of a dysphagia screening tool for patients with stroke.
Martino R, Silver F, Teasell R, Bayley M, Nicholson G, Streiner DL, Diamant NE
Stroke 2009 Feb;40(2):555-61. Epub 2008 Dec 12 doi: 10.1161/STROKEAHA.107.510370. PMID: 19074483
Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen.
Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M
Stroke 2007 Nov;38(11):2948-52. Epub 2007 Sep 20 doi: 10.1161/STROKEAHA.107.483933. PMID: 17885261
Tonsillar ectopia and headaches.
Arnett BC
Neurol Clin 2004 Feb;22(1):229-36. doi: 10.1016/S0733-8619(03)00101-4. PMID: 15062536

Recent systematic reviews

Clinical Predictors of Dysphagia Recovery After Stroke: A Systematic Review.
D'Netto P, Rumbach A, Dunn K, Finch E
Dysphagia 2023 Feb;38(1):1-22. Epub 2022 Apr 20 doi: 10.1007/s00455-022-10443-3. PMID: 35445366Free PMC Article
Screening for aspiration risk associated with dysphagia in acute stroke.
Boaden E, Burnell J, Hives L, Dey P, Clegg A, Lyons MW, Lightbody CE, Hurley MA, Roddam H, McInnes E, Alexandrov A, Watkins CL
Cochrane Database Syst Rev 2021 Oct 18;10(10):CD012679. doi: 10.1002/14651858.CD012679.pub2. PMID: 34661279Free PMC Article
Consensus on the treatment of dysphagia in Parkinson's disease.
Schindler A, Pizzorni N, Cereda E, Cosentino G, Avenali M, Montomoli C, Abbruzzese G, Antonini A, Barbiera F, Benazzo M, Benarroch E, Bertino G, Clavè P, Cortelli P, Eleopra R, Ferrari C, Hamdy S, Huckabee ML, Lopiano L, Marchese-Ragona R, Masiero S, Michou E, Occhini A, Pacchetti C, Pfeiffer RF, Restivo DA, Rondanelli M, Ruoppolo G, Sandrini G, Schapira A, Stocchi F, Tolosa E, Valentino F, Zamboni M, Zangaglia R, Zappia M, Tassorelli C, Alfonsi E
J Neurol Sci 2021 Nov 15;430:120008. Epub 2021 Sep 27 doi: 10.1016/j.jns.2021.120008. PMID: 34624796
Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.
Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508Free PMC Article
Dysphagia after stroke: incidence, diagnosis, and pulmonary complications.
Martino R, Foley N, Bhogal S, Diamant N, Speechley M, Teasell R
Stroke 2005 Dec;36(12):2756-63. Epub 2005 Nov 3 doi: 10.1161/01.STR.0000190056.76543.eb. PMID: 16269630

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