|
| Status |
Public on Jan 26, 2007 |
| Title |
Expression data in the absence of Notch1 in hair follicles |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Notch1 deficient hair matrix keratinocytes have lower mitotic rates, resulting in smaller follicles with fewer cells. In addition, the ratio of melanocytes to keratinocytes is greatly reduced. Microarray was performed to study downstream mechanism of Notch1-deficiency
Keywords: genetic modification
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| |
|
| Overall design |
Microarray was first performed using HF_emN1-1 and HF_anN1-1 samples. Later, HF_emN1-2, HF_anN1-2, HF_WT-1, and HF_WT-2 were used to perform another set of microarray. anN1s and WTs were used as wild-type controls.
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| |
|
| Citation(s) |
17611229 |
| Submission date |
Jan 25, 2007 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Raphael Kopan |
| E-mail(s) |
raphael.kopan@cchmc.org
|
| Organization name |
Cincinnati Children's Hospital
|
| Department |
Developmental Biology
|
| Lab |
Kopan Lab
|
| Street address |
3333 Burnet Avenue
|
| City |
Cincinnati |
| State/province |
Ohio |
| ZIP/Postal code |
45011 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
|
| Samples (6)
|
| GSM158357 |
emN1 P9 hair follicle, biological rep1 |
| GSM158359 |
anN1 P9 hair follicle, biological rep1 |
| GSM158360 |
emN1 P9 hair follicle, biological rep2 |
| GSM158361 |
anN1 P9 hair follicle, biological rep2 |
| GSM158362 |
wild-type P9 hair follicle, biological rep1 |
| GSM158363 |
wild-type P9 hair follicle, biological rep2 |
|
| Relations |
| BioProject |
PRJNA99119 |
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