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| Status |
Public on Sep 04, 2018 |
| Title |
Genome-wide gene expression profiles of 14 paired (normal and varicose) vein samples from the patients with varicose vein disease. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To identify genes whose products are involved in the formation of a pathological phenotype of varicose veins, we attempted to analyze the transcriptome of their constituent cells and compare it to the transcriptome of normal veins from the same patient. We identified a number of genes of extracellular matrix remodeling and cell-cell communication significantly changing gene expression status in disease condition.
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| Overall design |
7 pairs (14) of RNA samples of varicose and normal veins were tested on the gene expression beadchips.
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| Contributor(s) |
Smetanina MA |
| Citation(s) |
30070582 |
| Submission date |
Apr 27, 2015 |
| Last update date |
Sep 05, 2018 |
| Contact name |
Mariya Alexandrovna Smetanina |
| Organization name |
Institute of Chemical Biology and Fundamental Medicine SB RAS
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| Lab |
Laboratory of Pharmacogenomics
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| Street address |
8 Lavrentiev Avenue
|
| City |
Novosibirsk |
| ZIP/Postal code |
630090 |
| Country |
Russia |
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| Platforms (1) |
| GPL6883 |
Illumina HumanRef-8 v3.0 expression beadchip |
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| Samples (14)
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| This SubSeries is part of SuperSeries: |
| GSE68372 |
Profiles of 20 paired (normal and varicose) vein samples from the patients with varicose vein disease |
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| Relations |
| BioProject |
PRJNA282528 |
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