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Series GSE59901 Query DataSets for GSE59901
Status Public on Nov 30, 2014
Title DNA methylation study in breast cancer [methylation]
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Addressing the still unresolved question of the existence of CIMP in breast cancer DNA methylation alterations among histological breast cancer subtypes were examined by applying the HM450K BeadChip of Illumina Inc., covering about 480,000 single CpG sites. In addition to the occurrence of the hypermethylator phenotype in breast cancer, its relation to genetic instability and histological subtypes was investigated.
Overall design Bisulfite converted DNA from 32 fresh-frozen primary breast tissue samples and 4 breast cancer cell lines were hybridized onto the HumanMethylation 450K BeadChip from Illumina Inc. Additionally, 28 of these primary samples were analyzed by array-based comparative hybdridization (aCGH).
Contributor(s) Rößler J, Lehmann U, Ammerpohl O, Gutwein J, Steinemann D
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Submission date Jul 30, 2014
Last update date Mar 22, 2019
Contact name Jessica Rößler
Organization name Medical School Hannover
Department Pathology
Street address Carl-Neuberg Str. 1
City Hannover
ZIP/Postal code 30625
Country Germany
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (36)
GSM1450436 TU_BRCA1_1
GSM1450437 TU_BRCA1_3
GSM1450438 TU_BRCA1_2
This SubSeries is part of SuperSeries:
GSE59903 DNA methylation study in breast cancer
BioProject PRJNA257041

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE59901_450K_MethylationData_raw.csv.gz 391.5 Mb (ftp)(http) CSV
GSE59901_RAW.tar 183.1 Mb (http)(custom) TAR
Processed data included within Sample table

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