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| Status |
Public on Jun 21, 2014 |
| Title |
GTF2I Mutations are Common in Thymic Epithelial Tumors |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by genome tiling array
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| Summary |
Within a project aim to define the genomic aberration of thymic epithelial tumors, we performed array CGH in 65 thymic epithelial tumors. Tumor samples were collected during surgery or by image-guided biopsies and immediately frozen. Section from frozen material were cut and stained with Haematoxylin and Eosin. A pathologist reviewed the slides and selected only cases with >80% of cancer cells.
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| Overall design |
Copy number aberrations of a series of 65 thymic epithelial tumors were evaluated using array CGH. Differences in copy number aberrations between different histotypes were evaluated. Significant regions of CN aberrations were defined using GISTIC algorithms.
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| Contributor(s) |
Petrini I, Meltzer PS, Kim IK, Lucchi M, Fontanini G, Gao J, Zucali PA, Calabrese F, Favaretto A, Federico R, Rodriguez-Canales J, Walker RL, Pineda M, Zhu YJ, Lau C, Killian KJ, Bilke S, Voeller D, Dakshanamurthy S, Wang Y, Giaccone G |
| Citation(s) |
24974848 |
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| Submission date |
Mar 13, 2014 |
| Last update date |
Oct 31, 2014 |
| Contact name |
Iacopo Petrini |
| E-mail(s) |
i.petrini@sssup.it
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| Phone |
00393428566432
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| Organization name |
Pisa University
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| Street address |
Via Roma 67
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| City |
Pisa |
| ZIP/Postal code |
56100 |
| Country |
Italy |
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| Platforms (1) |
| GPL10123 |
Agilent-022060 SurePrint G3 Human CGH Microarray 4x180K (Feature Number version) |
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| Samples (65)
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| Relations |
| BioProject |
PRJNA241155 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE55852_RAW.tar |
1.1 Gb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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