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Series GSE45727 Query DataSets for GSE45727
Status Public on Nov 04, 2013
Title NLRP7 promotes trophoblast lineage differentiation, YY1 binding and alters CpG methylation
Organism Homo sapiens
Experiment type Methylation profiling by array
Summary Genome wide DNA methylation profiling of hESC in the untransduced, scrambled control and with knockdown of NLRP7 in undifferentiated and BMP4 differentiated states using the Illumina HumanMethylation 450 BeadChip. Several genomic sites exhibit altered methylation upon knocking down NLRP7.
Overall design Bisulphite converted DNA from 3 replicates of untransduced, scrambled control and NLRP7 knockdown in the undifferentiated and BMP differentiated groups were hybridised to the Illumina Human Methylation 450 Beadchip.
Contributor(s) Mahadevan S, Wen S, Wan Y, Peng H, Otta S, Liu Z, Iacovino M, Mahen EM, Kyba M, Sadikovic B, Van den Veyver IB
Citation(s) 24105472
Submission date Apr 03, 2013
Last update date Mar 22, 2019
Contact name Sangeetha Kaveri Mahadevan
Organization name Baylor College of Medicine
Department Obsterics and Gynecology
Lab Ignatia Van den Veyver
Street address 1250 Moursund St, Room 1025
City Houston
State/province Texas
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (18)
GSM1113249 genomic DNA from undifferentiated, untransduced H9 hESC, replicate A
GSM1113250 genomic DNA from undifferentiated, scrambled H9 hESC, replicate A
GSM1113251 genomic DNA from undifferentiated, NLRP7 knockdown H9 hESC, replicate A
BioProject PRJNA196136

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE45727_RAW.tar 183.1 Mb (http)(custom) TAR
GSE45727_non_normalized_array1.txt.gz 19.5 Mb (ftp)(http) TXT
GSE45727_non_normalized_array2.txt.gz 33.1 Mb (ftp)(http) TXT
Processed data included within Sample table

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