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| Status |
Public on Nov 12, 2012 |
| Title |
Identification of target genes of cancer-related microRNAs in human cancer |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To identify target genes of cancer-related microRNAs in human cancer, several cell lines (bladder cancer, prostate cancer, renal cell carcinoma, esophageal squamous cell carcinoma, and head and neck squamous cell carcinoma) were subjected to Agilent whole genome microarrays.
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| Overall design |
Human cancer cell lines (BOY, T24, A498, 786-O, caki-1, LNCap, PC3, TE2, T.Tn, FaDu, SAS, HSC3, and IMC-3) were transfected with miRNAs (miR-375, miR-145, miR-200a, miR-200b, miR-200c, miR-141, miR-429, miR-138, miR-218, miR-874, miR-31, miR-222, miR-1285, and miR-206) or siRNAs (si-FOXA1_1, si-FOXA1_3, and si-TAGLN2). The miRNA-transfected human cancer cell lines were compared to control cell lines.
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| Contributor(s) |
Seki N |
| Citation(s) |
22766839, 22294552, 21922130, 23159910, 22854542, 24647829, 23558898, 23176581 |
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| Submission date |
Apr 09, 2012 |
| Last update date |
Nov 24, 2020 |
| Contact name |
Naohiko Seki |
| E-mail(s) |
naoseki@faculty.chiba-u.jp
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| Phone |
81-43-226-2971
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| Fax |
81-43-227-3442
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| Organization name |
Chiba University
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| Department |
School of Medicine
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| Lab |
Functional Genomics
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| Street address |
1-8-1 Inohana,Chuo-ku
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| City |
Chiba |
| State/province |
Chiba |
| ZIP/Postal code |
260-8670 |
| Country |
Japan |
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| Platforms (2) |
| GPL10332 |
Agilent-026652 Whole Human Genome Microarray 4x44K v2 (Feature Number version) |
| GPL13607 |
Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Feature Number version) |
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| Samples (35)
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| GSM911052 |
Identification of miR-375 target genes in HNSCC, IMC-3 |
| GSM911053 |
Identification of miR-145 target genes in HNSCC, IMC-3 |
| GSM911054 |
Identification of differentially expressed genes by knocking down of FOXA1 in prostate cancer, LNCap [si-FOXA1_1] |
| GSM911055 |
Identification of differentially expressed genes by knocking down of FOXA1 in prostate cancer, LNCap [si-FOXA1_3] |
| GSM911056 |
Identification of miR-874 target genes in HNSCC, SAS |
| GSM911057 |
Identification of miR-874 target genes in HNSCC, FaDu |
| GSM911058 |
Identification of miR-31 target genes in prostate cancer, PC3 |
| GSM911059 |
Identification of miR-222 target genes in prostate cancer, PC3 |
| GSM911060 |
Identification of miR-375 target genes in esophageal squamous cell carcinoma, T.Tn |
| GSM911061 |
Identification of miR-375 target genes in esophageal squamous cell carcinoma, TE2 |
| GSM911062 |
Identification of differentially expressed genes by knocking down of TAGLN2 in HNSCC, HSC3 |
| GSM911063 |
Identification of differentially expressed genes by knocking down of TAGLN2 in HNSCC, FaDu |
| GSM911064 |
Identification of miR-1285 target genes in renal cell carcinoma, A498 |
| GSM911065 |
Identification of miR-1285 target genes in renal cell carcinoma, 786-O |
| GSM911066 |
Identification of differentially expressed genes by knocking down of TAGLN2 in bladder cancer, BOY |
| GSM911067 |
Identification of differentially expressed genes by knocking down of TAGLN2 in bladder cancer, T24 |
| GSM911068 |
Identification of miR-206 target genes in renal cell carcinoma, A498 |
| GSM911069 |
Identification of miR-200c target genes in renal cell carcinoma, A498 |
| GSM911070 |
Identification of miR-429 target genes in renal cell carcinoma, A498 |
| GSM911071 |
Identification of miR-218 target genes in renal cell carcinoma, A498 |
| GSM911072 |
Identification of miR-200a target genes in renal cell carcinoma, A498 |
| GSM911073 |
Identification of miR-200b target genes in renal cell carcinoma, A498 |
| GSM911074 |
Identification of miR-141 target genes in renal cell carcinoma, A498 |
| GSM911075 |
Identification of miR-138 target genes in renal cell carcinoma, A498 |
| GSM911076 |
Identification of miR-218 target genes in HNSCC, FaDu |
| GSM911077 |
Identification of miR-218 target genes in HNSCC, SAS |
| GSM911078 |
Identification of miR-200a target genes in renal cell carcinoma, caki-1 |
| GSM911079 |
Identification of miR-200b target genes in renal cell carcinoma, caki-1 |
| GSM911080 |
Identification of miR-200c target genes in renal cell carcinoma, caki-1 |
| GSM911081 |
Identification of miR-141 target genes in renal cell carcinoma, caki-1 |
| GSM911082 |
Identification of miR-429 target genes in renal cell carcinoma, caki-1 |
| GSM911083 |
Identification of miR-1291 target genes in renal cell carcinoma, A498 |
| GSM911084 |
Identification of miR-1291 target genes in renal cell carcinoma, 786-O |
| GSM911085 |
Identification of miR-504 target genes in HNSCC, FaDu |
| GSM911086 |
Identification of miR-504 target genes in HNSCC, SAS |
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| Relations |
| BioProject |
PRJNA158277 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE37119_RAW.tar |
633.3 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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