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Series GSE16670 Query DataSets for GSE16670
Status Public on Jun 24, 2009
Title Responsiveness of a frog cell line to the AHR ligands FICZ and TCDD
Organism Xenopus laevis
Experiment type Expression profiling by array
Summary The aryl hydrocarbon receptor (AHR) mediates the toxic effects of environmental contaminants, such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Frogs are very insensitive to the toxic effects of TCDD.
Overall design XLK-WG cells (ATCC) were grown to ~90% confluence in RPMI-1640 media supplemented with 20% FBS at 29 degrees and 5% CO2. Cells were subsequently exposed to 100 nM TCDD, FICZ, or DMSO vehicle (0.25%) for 3 hr prior to extraction of total RNA.
Study included three complete biological replicates of each treatment.
Contributor(s) Laub LB, Jones BD, Boundarant SS, Powell WH
Citation(s) 19799885
Submission date Jun 17, 2009
Last update date Sep 25, 2019
Contact name Wade H Powell
Phone 740-427-5396
Fax 740-427-5741
Organization name Kenyon College
Department Biology Dept.
Street address 302A College Park St.
City Gambier
State/province OH
ZIP/Postal code 43022
Country USA
Platforms (1)
GPL1318 [Xenopus_laevis] Affymetrix Xenopus laevis Genome Array
Samples (9)
GSM417875 DMSO CH 1
GSM417876 DMSO CH 2
GSM417877 DMSO CH 3
BioProject PRJNA117383

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE16670_RAW.tar 19.1 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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