GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE118814 Query DataSets for GSE118814
Status Public on Feb 24, 2020
Title MicroRNA-7 regulates the plasticity of the enteroendocrine lineage
Organisms Drosophila melanogaster; Mus musculus
Experiment type Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
Summary Systematic evaluation of the cell populations of the intestinal crypt confirms the plasticity of the EEC progenitors, and uncovering of a functional role for the evolutionarily consvered miRNA-7 in this context.
Overall design Separation of mouse intestinal crypts into subpopulations based on expression of Sox9-EGFP, LgR5, or Prox1. Fruit fly midgut was dissected prior to and at various time point following infection by Ecc15. Single cell RNA-seq of enteroids treated by LNAs.
Contributor(s) Sethupathy P, Kanke M
Citation(s) 31756561
Submission date Aug 20, 2018
Last update date Feb 24, 2020
Contact name Praveen Sethupathy
Organization name Cornell University
Lab Dr. Sethupathy Lab
Street address Cornell University College of Veterinary Medicine, Box 17
City Ithica
State/province NY
ZIP/Postal code 14853
Country USA
Platforms (4)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
GPL17275 Illumina HiSeq 2500 (Drosophila melanogaster)
Samples (49)
GSM3348104 Sox9eGFP Low Female Chow Rep #1
GSM3348105 Sox9eGFP Low Female HFD Rep #1
GSM3348106 Sox9eGFP Low Female HFD Rep #2
BioProject PRJNA486848
SRA SRP158442

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE118814_Lgr5_RPMMM_mirs_over_50.csv.gz 3.1 Kb (ftp)(http) CSV
GSE118814_Prox1_RPMMM_mirs_over_50.csv.gz 7.6 Kb (ftp)(http) CSV
GSE118814_RAW.tar 1.8 Mb (http)(custom) TAR (of MTX, TSV)
GSE118814_Sox9_HFD_RNAseq_normalized_counts.csv.gz 1.4 Mb (ftp)(http) CSV
GSE118814_Sox9_HFD_RPMMM_mirs_over_50.csv.gz 9.2 Kb (ftp)(http) CSV
GSE118814_Sox9_sorted_males_RPMMM_over_50.csv.gz 16.5 Kb (ftp)(http) CSV
GSE118814_drosophilia_infection_RPMMM_mirs_over_50.csv.gz 4.7 Kb (ftp)(http) CSV
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record
Processed data provided as supplementary file

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap