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| Status |
Public on Feb 06, 2020 |
| Title |
Transcriptomic and epigenetic profiling of genome control in the germline stem cell cycle in mice [ChIP-seq] |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
The faithful transmission of genome information is fundamental to the germline stem cell cycle. One exception to this is meiosis when active recombination takes place. This study aims to understand how dna damage responses and meiotic recombination mechanisms are properly coordinated with developmental programs of germ cells by comparing transcriptomic and epigenetic profiles of germline competent pluripotent stem cells, germline stem cells and somatic cells etc. in mice.
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| Overall design |
Histone modification and transcription factor binding profiles of mouse germline stem (GS) cells treated with or without retinoic acid were generated by Illumina deep sequencing.
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| Contributor(s) |
Chuma S, Hosokawa M |
| Citation missing |
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| |
| Submission date |
Jul 09, 2018 |
| Last update date |
Feb 07, 2020 |
| Contact name |
Shinichiro Chuma |
| E-mail(s) |
chuma.shinichiro.3x@kyoto-u.ac.jp
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| Phone |
+81-75-751-3821
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| Organization name |
Kyoto university
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| Department |
Institute for Frontier Life and Medical Sciences
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| Lab |
Laboratory of Developmental Epigenome
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| Street address |
53 Kawahara-cho, Shogoin, Sakyo-ku
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| City |
Kyoto |
| State/province |
Kyoto |
| ZIP/Postal code |
606-8507 |
| Country |
Japan |
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| Platforms (2) |
| GPL11002 |
Illumina Genome Analyzer IIx (Mus musculus) |
| GPL16417 |
Illumina MiSeq (Mus musculus) |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE116798 |
Transcriptomic and epigenetic profiling of genome control in the germline stem cell cycle in mice |
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| Relations |
| BioProject |
PRJNA480262 |
| SRA |
SRP152839 |
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