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rev Rev [ Human immunodeficiency virus 1 ]

Gene ID: 155908, updated on 7-Aug-2024

Summary

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Gene symbol
rev
Gene description
Rev
Locus tag
HIV1gp6
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Human immunodeficiency virus 1
Lineage
Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Lentivirus; Primate lentivirus group
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Genomic context

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Sequence:
NC_001802.1 (5516..8199)

NC_001802.1Genomic Context describing neighboring genes Neighboring gene Gag-Pol Neighboring gene Pr55(Gag) Neighboring gene Vif Neighboring gene Vpr Neighboring gene Tat Neighboring gene Vpu Neighboring gene Envelope surface glycoprotein gp160, precursor Neighboring gene Asp Neighboring gene Nef

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001802.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Randomized codon mutagenesis reveals that the HIV Rev arginine-rich motif is robust to substitutions and that double substitution of two critical residues alters specificity. Possik EJ, et al. J Mol Recognit, 2013 Jun. PMID 23595810
  2. RTE and CTE mRNA export elements synergistically increase expression of unstable, Rev-dependent HIV and SIV mRNAs. Smulevitch S, et al. Retrovirology, 2006 Jan 13. PMID 16412225, Free PMC Article
  3. RNA-guided assembly of Rev-RRE nuclear export complexes. Bai Y, et al. Elife, 2014 Aug 27. PMID 25163983, Free PMC Article
  4. Analysis of the influence of subcellular localization of the HIV Rev protein on Rev-dependent gene expression by multi-fluorescence live-cell imaging. Wolff H, et al. Exp Cell Res, 2006 Feb 15. PMID 16368434
  5. Functional analysis of backbone cyclic peptides bearing the arm domain of the HIV-1 Rev protein: characterization of the karyophilic properties and inhibition of Rev-induced gene expression. Hariton-Gazal E, et al. Biochemistry, 2005 Aug 30. PMID 16114892

See all (254) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rev Protein Diversity in HIV-1 Group M Clades.
    Title: Rev Protein Diversity in HIV-1 Group M Clades.
  2. Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
    Title: Structural basis of microtubule depolymerization by the kinesin-like activity of HIV-1 Rev.
  3. CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev.
    Title: CBP80/20-dependent translation initiation factor (CTIF) inhibits HIV-1 Gag synthesis by targeting the function of the viral protein Rev.
  4. CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs.
    Title: CRNKL1 Is a Highly Selective Regulator of Intron-Retaining HIV-1 and Cellular mRNAs.
  5. Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.
    Title: Sequence and Functional Variation in the HIV-1 Rev Regulatory Axis.
  6. HIV-1 resists MxB inhibition of viral Rev protein.
    Title: HIV-1 resists MxB inhibition of viral Rev protein.
  7. Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA.
    Title: Native mass spectrometry reveals the initial binding events of HIV-1 rev to RRE stem II RNA.
  8. Premature Stop Codon at Residue 101 within HIV-1 Rev Does Not Influence Viral Replication of Clade BC but Severely Reduces Viral Fitness of Clade B.
    Title: Premature Stop Codon at Residue 101 within HIV-1 Rev Does Not Influence Viral Replication of Clade BC but Severely Reduces Viral Fitness of Clade B.
  9. Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability.
    Title: Highly Mutable Linker Regions Regulate HIV-1 Rev Function and Stability.
  10. ANP32A and ANP32B mediate the export of unspliced or partially spliced viral mRNA via interactions with Rev and CRM1.
    Title: ANP32A and ANP32B are key factors in the Rev-dependent CRM1 pathway for nuclear export of HIV-1 unspliced mRNA.
Submit: New GeneRIF Correction See all GeneRIFs (80)

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
ATP-binding cassette sub-family F member 1 isoform b ABCF1 interacts with PubMed
apoptotic chromatin condensation inducer in the nucleus isoform 1 ACIN1 interacts with PubMed
actin, cytoplasmic 1 ACTB associates with PubMed
ACTB associates with PubMed
ACTB associates with PubMed
double-stranded RNA-specific adenosine deaminase isoform a ADAR interacts with PubMed
ADAR regulated by PubMed
arf-GAP domain and FG repeat-containing protein 1 isoform 2 AGFG1 binds PubMed
AGFG1 binds PubMed
AGFG1 binds PubMed
AGFG1 requires PubMed
arf-GAP domain and FG repeat-containing protein 2 AGFG2 binds PubMed
AGFG2 binds PubMed
THO complex subunit 4 ALYREF inhibits PubMed
S-adenosylmethionine decarboxylase proenzyme isoform 1 AMD1 requires PubMed
acidic leucine-rich nuclear phosphoprotein 32 family member A ANP32A interacts with PubMed
ANP32A interacts with PubMed
acidic leucine-rich nuclear phosphoprotein 32 family member B ANP32B interacts with PubMed
ANP32B interacts with PubMed
acidic leucine-rich nuclear phosphoprotein 32 family member E isoform 1 ANP32E interacts with PubMed
DNA repair nuclease/redox regulator APEX1 APEX1 interacts with PubMed
serine-protein kinase ATM isoform a ATM stimulated by PubMed
sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform a ATP2A2 interacts with PubMed
complement component 1 Q subcomponent-binding protein, mitochondrial precursor C1QBP binds PubMed
C1QBP inhibits PubMed
C1QBP binds PubMed
C1QBP binds PubMed
ashwin isoform 1 C2orf49 interacts with PubMed
calreticulin precursor CALR interacts with PubMed
caprin-1 isoform 1 CAPRIN1 interacts with PubMed
cell division cycle 5-like protein CDC5L interacts with PubMed
cyclin-dependent kinase 1 isoform 1 CDK1 phosphorylated by PubMed
small ribosomal subunit protein mS37 CHCHD1 interacts with PubMed
cleavage and polyadenylation specificity factor subunit 2 isoform 1 CPSF2 interacts with PubMed
cleavage and polyadenylation specificity factor subunit 6 isoform 1 CPSF6 interacts with PubMed
cleavage and polyadenylation specificity factor subunit 7 isoform 1 CPSF7 interacts with PubMed
casein kinase II subunit alpha isoform a CSNK2A1 interacts with PubMed
CSNK2A1 modulated by PubMed
CSNK2A1 activates PubMed
CSNK2A1 phosphorylated by PubMed
CSNK2A1 binds PubMed
CSNK2A1 phosphorylated by PubMed
casein kinase II subunit alpha' CSNK2A2 interacts with PubMed
CSNK2A2 modulated by PubMed
CSNK2A2 activates PubMed
CSNK2A2 phosphorylated by PubMed
CSNK2A2 binds PubMed
CSNK2A2 phosphorylated by PubMed
casein kinase II subunit beta isoform 1 CSNK2B interacts with PubMed
CSNK2B activates PubMed
CSNK2B phosphorylated by PubMed
CSNK2B binds PubMed
CSNK2B phosphorylated by PubMed
CSNK2B modulated by PubMed
cleavage stimulation factor subunit 2 isoform 2 CSTF2 interacts with PubMed
cleavage stimulation factor subunit 3 isoform 1 CSTF3 interacts with PubMed
cullin-4A isoform 2 CUL4A interacts with PubMed
cullin-4B isoform 1 CUL4B interacts with PubMed
C-X-C chemokine receptor type 4 isoform b CXCR4 inhibits PubMed
DAZ-associated protein 1 isoform b DAZAP1 interacts with PubMed
DNA damage-binding protein 1 DDB1 interacts with PubMed
ATP-dependent RNA helicase DDX1 DDX1 interacts with PubMed
DDX1 binds PubMed
DDX1 co-localizes with PubMed
DDX1 interacts with PubMed
DDX1 interacts with PubMed
DDX1 interacts with PubMed
DDX1 interacts with PubMed
DDX1 relocalized by PubMed
DDX1 relocalized by PubMed
DDX1 interacts with PubMed
probable ATP-dependent RNA helicase DDX17 isoform 1 precursor DDX17 cooperates with PubMed
DDX17 interacts with PubMed
DDX17 interacts with PubMed
nucleolar RNA helicase 2 isoform 1 DDX21 enhanced by PubMed
DDX21 interacts with PubMed
ATP-dependent RNA helicase DDX24 DDX24 interacts with PubMed
DDX24 interacts with PubMed
spliceosome RNA helicase DDX39B DDX39B inhibits PubMed
ATP-dependent RNA helicase DDX3X isoform 1 DDX3X inhibited by PubMed
DDX3X interacts with PubMed
DDX3X cooperates with PubMed
DDX3X enhanced by PubMed
DDX3X interacts with PubMed
DDX3X regulated by PubMed
DDX3X exported by PubMed
DDX3X interacts with PubMed
probable ATP-dependent RNA helicase DDX47 isoform 1 DDX47 interacts with PubMed
probable ATP-dependent RNA helicase DDX5 isoform a DDX5 enhanced by PubMed
DDX5 interacts with PubMed
DDX5 enhanced by PubMed
DDX5 interacts with PubMed
probable ATP-dependent RNA helicase DDX56 isoform 1 DDX56 interacts with PubMed
ATP-dependent DNA/RNA helicase DHX36 isoform 1 DHX36 interacts with PubMed
ATP-dependent RNA helicase A DHX9 regulated by PubMed
DHX9 interacts with PubMed
DHX9 interacts with PubMed
endoribonuclease Dicer isoform 1 DICER1 inhibits PubMed
dnaJ homolog subfamily A member 1 isoform 1 DNAJA1 inhibited by PubMed
dnaJ homolog subfamily B member 6 isoform b DNAJB6 inhibited by PubMed
cytoplasmic dynein 1 heavy chain 1 DYNC1H1 interacts with PubMed
elongation factor 1-alpha 1 EEF1A1 interacts with PubMed
eukaryotic translation initiation factor 2 subunit 2 isoform 1 EIF2S2 interacts with PubMed
eukaryotic translation initiation factor 2 subunit 3 EIF2S3 interacts with PubMed
eukaryotic translation initiation factor 3 subunit I isoform 1 EIF3I interacts with PubMed
eukaryotic translation initiation factor 3 subunit M isoform 1 EIF3M interacts with PubMed
eukaryotic translation initiation factor 5A-1 isoform B EIF5A binds PubMed
EIF5A interacts with PubMed
EIF5A interacts with PubMed
EIF5A binds PubMed
EIF5A interacts with PubMed
EIF5A binds PubMed
ribosomal RNA small subunit methyltransferase NEP1 isoform 1 EMG1 interacts with PubMed
epsin-2 isoform a EPN2 interacts with PubMed
general transcription and DNA repair factor IIH helicase subunit XPD isoform 1 ERCC2 interacts with PubMed
ERCC2 interacts with PubMed
general transcription and DNA repair factor IIH helicase/translocase subunit XPB isoform a ERCC3 interacts with PubMed
ERCC3 interacts with PubMed
enhancer of rudimentary homolog ERH interacts with PubMed
RNA-binding protein EWS isoform 2 EWSR1 interacts with PubMed
exosome complex component CSL4 isoform a EXOSC1 interacts with PubMed
exosome complex component RRP46 EXOSC5 interacts with PubMed
exosome complex component RRP42 EXOSC7 interacts with PubMed
protein FAM98B FAM98B interacts with PubMed
ubiquitin-like FUBI-ribosomal protein eS30 fusion protein precursor FAU interacts with PubMed
RNA-binding protein FUS isoform 1 FUS interacts with PubMed
glyceraldehyde-3-phosphate dehydrogenase isoform 1 GAPDH interacts with PubMed
G patch domain-containing protein 4 isoform 1 GPATCH4 interacts with PubMed
GPN-loop GTPase 1 isoform a GPN1 interacts with PubMed
histone H2A.J H2AJ interacts with PubMed
histone H2B type 1-M H2BC14 interacts with PubMed
histone H2B type 1-N H2BC15 interacts with PubMed
histone H2B type 2-F isoform a H2BC18 interacts with PubMed
histone H2B type 2-E H2BC21 interacts with PubMed
histone H2B type 3-B H2BC26 interacts with PubMed
histone H2B type 1-B H2BC3 interacts with PubMed
histone H2B type 1-C/E/F/G/I H2BC4 interacts with PubMed
histone H2B type 1-D H2BC5 interacts with PubMed
histone H2B type 1-H H2BC9 interacts with PubMed
histone H3.3 H3-3B interacts with PubMed
histone H3.1t H3-4 co-localizes with PubMed
histone H4 H4C1 interacts with PubMed
HCLS1-associated protein X-1 isoform a HAX1 co-localizes with PubMed
HAX1 binds PubMed
E3 ISG15--protein ligase HERC5 HERC5 relocalized by PubMed
hexokinase-2 isoform 1 HK2 interacts with PubMed
major histocompatibility complex, class I, B precursor HLA-B interacts with PubMed
HLA class I histocompatibility antigen, C alpha chain precursor HLA-C interacts with PubMed
heterogeneous nuclear ribonucleoprotein A1 isoform a HNRNPA1 interacts with PubMed
HNRNPA1 interacts with PubMed
HNRNPA1 modulated by PubMed
HNRNPA1 interacts with PubMed
HNRNPA1 stimulates PubMed
heterogeneous nuclear ribonucleoproteins A2/B1 isoform A2 HNRNPA2B1 interacts with PubMed
heterogeneous nuclear ribonucleoprotein A3 isoform a HNRNPA3 interacts with PubMed
heterogeneous nuclear ribonucleoprotein A/B isoform b HNRNPAB interacts with PubMed
heterogeneous nuclear ribonucleoproteins C1/C2 isoform b HNRNPC interacts with PubMed
heterogeneous nuclear ribonucleoprotein D0 isoform d HNRNPD interacts with PubMed
heterogeneous nuclear ribonucleoprotein D-like isoform a HNRNPDL interacts with PubMed
heterogeneous nuclear ribonucleoprotein F HNRNPF interacts with PubMed
heterogeneous nuclear ribonucleoprotein H isoform a HNRNPH1 interacts with PubMed
heterogeneous nuclear ribonucleoprotein H2 HNRNPH2 interacts with PubMed
heterogeneous nuclear ribonucleoprotein H3 isoform a HNRNPH3 interacts with PubMed
heterogeneous nuclear ribonucleoprotein K isoform a HNRNPK interacts with PubMed
HNRNPK interacts with PubMed
heterogeneous nuclear ribonucleoprotein M isoform a HNRNPM interacts with PubMed
heterogeneous nuclear ribonucleoprotein R isoform 2 HNRNPR interacts with PubMed
HNRNPR binds PubMed
heterogeneous nuclear ribonucleoprotein U isoform b HNRNPU interacts with PubMed
HNRNPU interacts with PubMed
endoplasmin precursor HSP90B1 interacts with PubMed
E3 ubiquitin-protein ligase HUWE1 HUWE1 interacts with PubMed
insulin-like growth factor 2 mRNA-binding protein 1 isoform 1 IGF2BP1 interacts with PubMed
insulin-like growth factor 2 mRNA-binding protein 2 isoform a IGF2BP2 inhibited by PubMed
protein Red IK interacts with PubMed
interleukin enhancer-binding factor 2 isoform 1 ILF2 interacts with PubMed
interleukin enhancer-binding factor 3 isoform a ILF3 interacts with PubMed
ILF3 inhibited by PubMed
ILF3 regulated by PubMed
ILF3 regulated by PubMed
ILF3 interacts with PubMed
importin-5 IPO5 binds PubMed
IPO5 inhibited by PubMed
importin-7 IPO7 interacts with PubMed
inosine triphosphate pyrophosphatase isoform a ITPA inhibits PubMed
KH domain-containing, RNA-binding, signal transduction-associated protein 1 isoform 1 KHDRBS1 requires PubMed
KHDRBS1 inhibited by PubMed
KHDRBS1 requires PubMed
KHDRBS1 modulated by PubMed
KHDRBS1 inhibited by PubMed
KHDRBS1 synergizes with PubMed
KHDRBS1 binds PubMed
KH domain-containing, RNA-binding, signal transduction-associated protein 2 isoform 2 KHDRBS2 enhanced by PubMed
KH domain-containing, RNA-binding, signal transduction-associated protein 3 KHDRBS3 enhanced by PubMed
kinesin-like protein KIF22 isoform 1 KIF22 binds PubMed
importin subunit alpha-5 KPNA1 interacts with PubMed
importin subunit alpha-1 KPNA2 interacts with PubMed
importin subunit alpha-3 KPNA4 interacts with PubMed
importin subunit alpha-7 KPNA6 interacts with PubMed
importin subunit beta-1 isoform 1 KPNB1 interacts with PubMed
KPNB1 binds PubMed
KPNB1 inhibited by PubMed
KPNB1 binds PubMed
KRR1 small subunit processome component homolog KRR1 binds PubMed
galectin-3 isoform 1 LGALS3 inhibits PubMed
DNA ligase 3 isoform beta precursor LIG3 interacts with PubMed
lamin isoform C LMNA binds PubMed
mitogen-activated protein kinase 1 MAPK1 phosphorylated by PubMed
mitogen-activated protein kinase 3 isoform 1 MAPK3 phosphorylated by PubMed
matrin-3 isoform a MATR3 regulated by PubMed
MATR3 interacts with PubMed
MATR3 interacts with PubMed
DNA replication licensing factor MCM3 isoform 1 MCM3 co-localizes with PubMed
myoD family inhibitor domain-containing protein isoform p40 MDFIC downregulated by PubMed
MDFIC inhibited by PubMed
MDFIC interacts with PubMed
microfibrillar-associated protein 1 MFAP1 interacts with PubMed
MIT domain-containing protein 1 isoform 1 MITD1 interacts with PubMed
helicase MOV-10 isoform 1 MOV10 requires PubMed
MOV10 interacts with PubMed
MOV10 upregulated by PubMed
DNA-3-methyladenine glycosylase isoform a MPG interacts with PubMed
large ribosomal subunit protein uL11m isoform a MRPL11 interacts with PubMed
large ribosomal subunit protein mL42 precursor MRPL42 interacts with PubMed
small ribosomal subunit protein bS1m MRPS28 interacts with PubMed
small ribosomal subunit protein uS9m MRPS9 interacts with PubMed
magnesium transporter MRS2 homolog, mitochondrial isoform b precursor MRS2 interacts with PubMed
exosome RNA helicase MTR4 MTREX interacts with PubMed
myb-binding protein 1A isoform 2 MYBBP1A interacts with PubMed
nucleosome assembly protein 1-like 1 isoform 1 NAP1L1 interacts with PubMed
NAP1L1 interacts with PubMed
nucleosome assembly protein 1-like 4 isoform 1 NAP1L4 interacts with PubMed
asparagine--tRNA ligase, cytoplasmic NARS1 interacts with PubMed
RNA cytidine acetyltransferase isoform a NAT10 interacts with PubMed
NF-kappa-B inhibitor alpha NFKBIA inhibited by PubMed
nipped-B-like protein isoform B NIPBL interacts with PubMed
nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 isoform 1 NMNAT1 interacts with PubMed
non-POU domain-containing octamer-binding protein isoform 1 NONO associates with PubMed
NONO interacts with PubMed
nucleolar protein 58 NOP58 interacts with PubMed
nucleolar protein 9 isoform 1 NOP9 interacts with PubMed
nucleophosmin isoform 1 NPM1 interacts with PubMed
NPM1 co-localizes with PubMed
NPM1 interacts with PubMed
NPM1 binds PubMed
NPM1 associates with PubMed
NPM1 binds PubMed
NPM1 stimulated by PubMed
NAD(P)H dehydrogenase NQO1 downregulates PubMed
nardilysin isoform a NRDC interacts with PubMed
nuclear pore complex protein Nup153 isoform 2 NUP153 inhibited by PubMed
NUP153 interacts with PubMed
nuclear pore complex protein Nup214 isoform 2 NUP214 interacts with PubMed
NUP214 interacts with PubMed
NUP214 inhibited by PubMed
NUP214 recruits PubMed
NUP214 inhibited by PubMed
nucleoporin NUP42 isoform 2 NUP42 interacts with PubMed
NUP42 interacts with PubMed
nuclear pore glycoprotein p62 NUP62 interacts with PubMed
nuclear pore complex protein Nup98 isoform 3 precursor NUP98 interacts with PubMed
NUP98 interacts with PubMed
NUP98 recruits PubMed
NUP98 inhibited by PubMed
nuclear RNA export factor 1 isoform 1 NXF1 inhibits PubMed
protein disulfide-isomerase precursor P4HB interacts with PubMed
polyadenylate-binding protein 1 PABPC1 interacts with PubMed
PABPC1 interacts with PubMed
phosphofurin acidic cluster sorting protein 1 PACS1 enhanced by PubMed
PAX3- and PAX7-binding protein 1 isoform 2 PAXBP1 interacts with PubMed
poly(rC)-binding protein 1 PCBP1 inhibits PubMed
PCBP1 modulated by PubMed
PCBP1 interacts with PubMed
poly(rC)-binding protein 2 isoform a PCBP2 interacts with PubMed
protein RRP5 homolog isoform 2 PDCD11 interacts with PubMed
ATP-dependent 6-phosphofructokinase, liver type isoform b PFKL interacts with PubMed
ATP-dependent 6-phosphofructokinase, platelet type isoform 1 PFKP interacts with PubMed
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 isoform 2 precursor PLOD1 interacts with PubMed
pleiotropic regulator 1 isoform 1 PLRG1 interacts with PubMed
bifunctional polynucleotide phosphatase/kinase PNKP interacts with PubMed
serum paraoxonase/arylesterase 2 isoform 1 PON2 interacts with PubMed
suppressor of SWI4 1 homolog isoform 1 PPAN interacts with PubMed
PPAN-P2RY11 protein isoform 1 PPAN-P2RY11 interacts with PubMed
peptidyl-prolyl cis-trans isomerase B precursor PPIB interacts with PubMed
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform 1 PPP2R2A interacts with PubMed
serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform a PPP2R2D interacts with PubMed
serine/threonine-protein phosphatase 6 catalytic subunit isoform b PPP6C interacts with PubMed
protein kinase C alpha type PRKCA phosphorylated by PubMed
DNA-dependent protein kinase catalytic subunit isoform 1 PRKDC interacts with PubMed
interferon-inducible double-stranded RNA-dependent protein kinase activator A isoform 1 PRKRA binds PubMed
protein arginine N-methyltransferase 6 PRMT6 methylated by PubMed
PRMT6 methylated by PubMed
serine/threonine-protein kinase PRP4 homolog PRP4K interacts with PubMed
pre-mRNA-processing factor 19 PRPF19 interacts with PubMed
U4/U6 small nuclear ribonucleoprotein Prp31 PRPF31 interacts with PubMed
pre-mRNA-processing factor 6 PRPF6 interacts with PubMed
pre-mRNA-processing-splicing factor 8 PRPF8 interacts with PubMed
PC4 and SFRS1-interacting protein isoform 1 PSIP1 complexes with PubMed
PSIP1 interacts with PubMed
paraspeckle component 1 isoform 1 PSPC1 interacts with PubMed
polypyrimidine tract-binding protein 1 isoform a PTBP1 interacts with PubMed
prostaglandin E synthase 3 isoform a PTGES3 interacts with PubMed
prothymosin alpha isoform 2 PTMA binds PubMed
transcriptional activator protein Pur-alpha PURA interacts with PubMed
PURA co-localizes with PubMed
transcriptional regulator protein Pur-beta PURB interacts with PubMed
small ribosomal subunit protein RACK1 RACK1 interacts with PubMed
GTP-binding nuclear protein Ran isoform 1 RAN binds PubMed
RAN binds PubMed
RAN interacts with PubMed
RAN enhanced by PubMed
RAN binds PubMed
ran-specific GTPase-activating protein isoform 2 RANBP1 competes with PubMed
E3 SUMO-protein ligase RanBP2 isoform 1 RANBP2 regulated by PubMed
ran GTPase-activating protein 1 RANGAP1 interacts with PubMed
RNA-binding protein 14 isoform 1 RBM14 enhanced by PubMed
RBM14 associates with PubMed
RBM14 enhanced by PubMed
RNA-binding protein 15 isoform 1 RBM15 interacts with PubMed
RNA-binding protein 39 isoform b RBM39 interacts with PubMed
RNA-binding protein 42 isoform 1 RBM42 interacts with PubMed
ATP-dependent DNA helicase Q1 RECQL interacts with PubMed
large ribosomal subunit protein uL22 isoform a RPL17 interacts with PubMed
large ribosomal subunit protein uL14 RPL23 interacts with PubMed
large ribosomal subunit protein eL27 RPL27 interacts with PubMed
large ribosomal subunit protein uL3 isoform a RPL3 interacts with PubMed
large ribosomal subunit protein eL32 RPL32 interacts with PubMed
large ribosomal subunit protein eL33 RPL35A interacts with PubMed
large ribosomal subunit protein uL18 RPL5 interacts with PubMed
large ribosomal subunit protein eL6 isoform 1 RPL6 interacts with PubMed
small ribosomal subunit protein eS17 RPS17 interacts with PubMed
small ribosomal subunit protein uS5 RPS2 interacts with PubMed
small ribosomal subunit protein uS12 RPS23 interacts with PubMed
small ribosomal subunit protein eS25 RPS25 interacts with PubMed
ubiquitin-ribosomal protein eS31 fusion protein precursor RPS27A interacts with PubMed
small ribosomal subunit protein eS1 isoform 1 RPS3A interacts with PubMed
small ribosomal subunit protein eS4, X isoform RPS4X interacts with PubMed
small ribosomal subunit protein uS7 RPS5 interacts with PubMed
small ribosomal subunit protein eS6 RPS6 interacts with PubMed
small ribosomal subunit protein uS2 isoform 1 RPSA interacts with PubMed
RNA-splicing ligase RtcB homolog RTCB interacts with PubMed
RNA transcription, translation and transport factor protein RTRAF interacts with PubMed
ruvB-like 1 isoform 1 RUVBL1 interacts with PubMed
scaffold attachment factor B1 isoform 3 SAFB interacts with PubMed
protein SET isoform 2 SET interacts with PubMed
splicing factor 3A subunit 1 SF3A1 interacts with PubMed
splicing factor 3A subunit 2 SF3A2 interacts with PubMed
splicing factor 3A subunit 3 isoform 1 SF3A3 interacts with PubMed
splicing factor, proline- and glutamine-rich SFPQ regulated by PubMed
SFPQ interacts with PubMed
WD40 repeat-containing protein SMU1 SMU1 interacts with PubMed
U5 small nuclear ribonucleoprotein 200 kDa helicase SNRNP200 interacts with PubMed
U5 small nuclear ribonucleoprotein 40 kDa protein SNRNP40 interacts with PubMed
U1 small nuclear ribonucleoprotein 70 kDa isoform 1 SNRNP70 interacts with PubMed
U2 small nuclear ribonucleoprotein A' SNRPA1 inhibits PubMed
U1 small nuclear ribonucleoprotein C SNRPC interacts with PubMed
small nuclear ribonucleoprotein E isoform 1 SNRPE interacts with PubMed
small nuclear ribonucleoprotein F isoform 1 SNRPF interacts with PubMed
small nuclear ribonucleoprotein G isoform a SNRPG interacts with PubMed
spermatogenesis-associated serine-rich protein 2 SPATS2 interacts with PubMed
spectrin alpha chain, non-erythrocytic 1 isoform 2 SPTAN1 interacts with PubMed
spectrin beta chain, non-erythrocytic 1 isoform 1 SPTBN1 interacts with PubMed
S1 RNA-binding domain-containing protein 1 SRBD1 interacts with PubMed
signal recognition particle subunit SRP54 isoform 1 SRP54 interacts with PubMed
signal recognition particle 9 kDa protein isoform 2 SRP9 interacts with PubMed
serine/arginine-rich splicing factor 1 isoform 1 SRSF1 inhibited by PubMed
SRSF1 interacts with PubMed
SRSF1 inhibits PubMed
SRSF1 requires PubMed
serine/arginine-rich splicing factor 2 SRSF2 inhibited by PubMed
SRSF2 co-localizes with PubMed
serine/arginine-rich splicing factor 5 isoform 1 SRSF5 requires PubMed
serine/arginine-rich splicing factor 6 SRSF6 inhibited by PubMed
serine/arginine-rich splicing factor 9 SRSF9 interacts with PubMed
lupus La protein SSB interacts with PubMed
SSB interacts with PubMed
single-stranded DNA-binding protein, mitochondrial precursor SSBP1 interacts with PubMed
double-stranded RNA-binding protein Staufen homolog 2 isoform e STAU2 interacts with PubMed
stress-induced-phosphoprotein 1 isoform b STIP1 interacts with PubMed
activated RNA polymerase II transcriptional coactivator p15 SUB1 interacts with PubMed
FACT complex subunit SPT16 SUPT16H interacts with PubMed
heterogeneous nuclear ribonucleoprotein Q isoform 1 SYNCRIP cooperates with PubMed
SYNCRIP interacts with PubMed
SYNCRIP binds PubMed
RISC-loading complex subunit TARBP2 isoform b TARBP2 interacts with PubMed
TARBP2 binds PubMed
protein-glutamine gamma-glutamyltransferase 2 isoform a TGM2 inhibited by PubMed
trimethylguanosine synthase isoform 1 TGS1 associates with PubMed
THO complex subunit 6 isoform 1 THOC6 interacts with PubMed
transmembrane emp24 domain-containing protein 10 precursor TMED10 interacts with PubMed
transmembrane emp24 domain-containing protein 4 isoform 1 precursor TMED4 interacts with PubMed
transmembrane emp24 domain-containing protein 9 precursor TMED9 interacts with PubMed
transportin-1 isoform 1 TNPO1 interacts with PubMed
TNPO1 binds PubMed
TNPO1 inhibited by PubMed
transportin-3 isoform 1 TNPO3 disrupts PubMed
TNPO3 binds PubMed
target of EGR1 protein 1 TOE1 interacts with PubMed
cellular tumor antigen p53 isoform a TP53 activates PubMed
pachytene checkpoint protein 2 homolog isoform 1 TRIP13 interacts with PubMed
TRMT1-like protein isoform 1 TRMT1L interacts with PubMed
tubulin alpha-1A chain isoform 1 TUBA1A interacts with PubMed
TUBA1A depolymerizes PubMed
tubulin alpha-1B chain TUBA1B interacts with PubMed
TUBA1B depolymerizes PubMed
tubulin alpha-1C chain isoform c TUBA1C interacts with PubMed
TUBA1C depolymerizes PubMed
tubulin alpha-3C chain TUBA3C depolymerizes PubMed
tubulin alpha-4A chain isoform 1 TUBA4A interacts with PubMed
TUBA4A depolymerizes PubMed
tubulin alpha-8 chain isoform 1 TUBA8 interacts with PubMed
TUBA8 depolymerizes PubMed
tubulin beta chain isoform b TUBB interacts with PubMed
tubulin beta-1 chain TUBB1 depolymerizes PubMed
tubulin beta-2A chain isoform 1 TUBB2A interacts with PubMed
TUBB2A depolymerizes PubMed
tubulin beta-2B chain TUBB2B interacts with PubMed
tubulin beta-3 chain isoform 1 TUBB3 interacts with PubMed
TUBB3 depolymerizes PubMed
tubulin beta-4A chain isoform 3 TUBB4A interacts with PubMed
TUBB4A depolymerizes PubMed
tubulin beta-4B chain TUBB4B interacts with PubMed
TUBB4B depolymerizes PubMed
tubulin beta-6 chain isoform 1 TUBB6 depolymerizes PubMed
tubulin beta-8 chain isoform 1 TUBB8 depolymerizes PubMed
splicing factor U2AF 35 kDa subunit isoform a U2AF1 interacts with PubMed
polyubiquitin-B precursor UBB ubiquitinated by PubMed
polyubiquitin-C UBC ubiquitinated by PubMed
ubiquitin D UBD ubiquitinated by PubMed
E3 ubiquitin-protein ligase UBR4 UBR4 interacts with PubMed
ubiquitin carboxyl-terminal hydrolase 39 isoform 1 USP39 interacts with PubMed
WASH complex subunit 2A isoform 1 WASHC2A inhibited by PubMed
WASHC2A co-localizes with PubMed
WASHC2A interacts with PubMed
WASH complex subunit 2C isoform 1 WASHC2C interacts with PubMed
WASHC2C inhibited by PubMed
WASHC2C co-localizes with PubMed
WD repeat-containing protein 3 WDR3 interacts with PubMed
WD repeat-containing protein 36 WDR36 interacts with PubMed
exportin-1 isoform 1 XPO1 binds PubMed
XPO1 complexes with PubMed
XPO1 associates with PubMed
XPO1 cooperates with PubMed
XPO1 interacts with PubMed
XPO1 binds PubMed
XPO1 binds PubMed
XPO1 interacts with PubMed
XPO1 co-localizes with PubMed
XPO1 regulated by PubMed
XPO1 recruits PubMed
XPO1 interacts with PubMed
XPO1 binds PubMed
XPO1 interacts with PubMed
XPO1 interacts with PubMed
XPO1 inhibited by PubMed
XPO1 modulated by PubMed
XPO1 interacts with PubMed
XPO1 regulated by PubMed
XPO1 regulated by PubMed
XPO1 co-localizes with PubMed
XPO1 exported by PubMed
XPO1 enhanced by PubMed
XPO1 interacts with PubMed
XPO1 binds PubMed
XPO1 interacts with PubMed

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Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General protein information

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Preferred Names
Rev

NCBI Reference Sequences (RefSeq)

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NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001802.1 Reference assembly

    Range
    5516..8199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_057854.1 Rev [Human immunodeficiency virus 1]

    See identical proteins and their annotated locations for NP_057854.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P04618
    UniProtKB/TrEMBL
    Q72501, Q77YF8
    Conserved Domains (1) summary
    pfam00424
    Location:1 → 91
    REV; REV protein (anti-repression trans-activator protein)
Nucleotide Protein
Heading Accession and Version

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