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Full record GDS1647

RPE65 null mutant model of Leber's congenital amaurosis

Analysis of retinas of RPE65 null mutants at 2, 4 and 6 months of age. RPE65 is highly expressed in retinal pigment epithelial cells. Mutations in REP65 cause 10-15% of Leber's congenital amaurosis (LCA) cases, a severe form of retinal dystrophy. Results provide insight into early LCA progression.

Organism:: Mus musculus

Type:: Expression profiling by array, transformed count, 3 age, 2 genotype/variation sets

Platform:: GPL1261
Series:: GSE3249
18 Samples

DataSet

Accession:: GDS1647

ID:: 1647

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RPE65 null mutant model of Leber's congenital amaurosis
RPE65 null mutant model of Leber's congenital amaurosis
Accession: GDS1647

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PopSet: 406598945

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