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Full record GDS5242

Interleukin-21 effect on STAT3-deficient naïve B cells from autosomal dominant hyper IgE syndrome patients

Analysis of naïve B cells purified from peripheral blood of AD-HIES patients with STAT3 loss-of-function mutation and then cultured with CD40 ligand alone or together with interleukin-21. Results provide insight into IL-21R/STAT3 signaling induced genes underlying naïve B cell differentiation.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 7 individual, 2 protocol sets
Platform:
GPL6244
Series:
GSE51587
14 Samples
Download data: CEL
DataSet
Accession:
GDS5242
ID:
5242

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