Similar studies for GEO DataSets (Select 2233) - GEO DataSets

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Items: 17

Select item 22331.

Circadian clock deficient Per2/Cry1 double mutant adrenal gland in constant darkness: time course

Analysis of adrenal glands of Per2/Cry1 double mutant animals at 46 and 54 hours after transferring the animals from a light-day cycle to constant darkness. Per2/Cry1 double mutants lack a circadian clock. Results identify clock-regulated genes in the adrenal that are not necessarily rhythmic.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 time sets

Platform:: GPL1261
Series:: GSE4239
6 Samples

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DataSet

Accession:: GDS2233

ID:: 2233

Select item 2000042532.

Wildtype and Per2Cry1 double mutant mice: temporal gene expression profiling of adrenal gland

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1261
30 Samples

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Series

Accession:: GSE4253

ID:: 200004253

Select item 2000042393.

Transcriptome regulation in the adrenal gland of circadian clock deficient Per2Cry1 double mutant mice

(Submitter supplied) This array set was used to determine clock regulated genes in the adrenal gland that are not necessarily rhythmic but still controlled by the circadian TTL. Keywords: comparative genomic hybridization / time series

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2233
Platform:: GPL1261
6 Samples

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Series

Accession:: GSE4239

ID:: 200004239

Select item 2000042384.

rhythmic transcriptome in the murine wt adrenal

(Submitter supplied) This study was performed to characterize the rhythmic transcirptome of the murine adrenal gland with a focus on the corticosterone synthesis pathway. Keywords: time course

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2232
Platform:: GPL1261
24 Samples

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Series

Accession:: GSE4238

ID:: 200004238

Select item 22325.

Adrenal gland in constant darkness: time course

Analysis of adrenal glands of wild type animals at various time points after transferring the animals from a light-day cycle to constant darkness. Results provide insight into the function of the adrenal cortical clock.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 12 time sets

Platform:: GPL1261
Series:: GSE4238
24 Samples

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DataSet

Accession:: GDS2232

ID:: 2232

Select item 2000016736.

Circadian Profiling of the Transcriptome in Immortalized Rat SCN Cells: Comparison to Long-Evans Rat SCN

(Submitter supplied) To determine whether immortalized cells derived from the rat SCN (SCN 2.2) retain intrinsic rhythm-generating properties characteristic of the SCN, oscillatory properties of the SCN2.2 transcriptome were analyzed and compared to those found in the rat SCN in vivo using rat U34A Affymetrix GeneChips. In this comparison, adult male Long-Evans rats (175-200g; N=45) were housed under a standard 12h light:12h dark photoperiod (LD 12:12; lights-on at 0600 hr). more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL85
18 Samples

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Series

Accession:: GSE1673

ID:: 200001673

Select item 2000016547.

Circadian Profiling of the Transcriptome in Immortalized Rat SCN Cells (3 biological replicates)

(Submitter supplied) To determine whether immortalized cells derived from the rat SCN (SCN 2.2) retain intrinsic rhythm-generating properties characteristic of the SCN, oscillatory properties of the SCN2.2 transcriptome were analyzed and compared to those found in the rat SCN in vivo using rat U34A Affymetrix GeneChips. SCN2.2 cells were expanded in 6-well plates. At 6-hour interval across 2 circadian cycles, cells from single 6-well plates were harvested and pooled for total RNA extraction. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Platform:: GPL85
27 Samples

Download data: CEL, EXP, RPT

Series

Accession:: GSE1654

ID:: 200001654

Select item 2000021628.

Two circadian oscillatory mechanisms in the mouse liver

(Submitter supplied) Genome-wide expression analysis of two circadian oscillatory mechanisms in the mouse liver To identify the genes of which the circadian expression is regulated by endogenous glucocorticoids, we performed DNA microarray analysis using hepatic RNA from adrenalectomized (ADX) and sham-operated mice. Mice were housed in a 12:12 h light-dark cycle (LD12:12; lights on at zeitgeber time (ZT) 0) for at least two weeks before the day of the experiment. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS1870
Platform:: GPL81
4 Samples

Download data: CEL, EXP, RPT, TXT

Series

Accession:: GSE2162

ID:: 200002162

Select item 18709.

Adrenalectomized liver at light and dark periods of the circadian cycle

Expression profiling of livers of adrenalectomized C57BL/6 males 2 hours into the light or dark periods of a 12:12 hour light cycle. Results identify genes regulated by endogenous glucocorticoids in a circadian manner.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 2 protocol, 2 time sets

Platform:: GPL81
Series:: GSE2162
4 Samples

Download data: CEL, EXP, RPT, TXT

DataSet

Accession:: GDS1870

ID:: 1870

Select item 20008153210.

Diurnal transcriptome rhythms in mice with genetically ablated clock function in the suprachiasmatic nucleus (SCN)

(Submitter supplied) Male KO (Syt10-Cre/Cre x Bmal1-flox/-) and CON (Syt10-Cre/Cre x Bmal1-+/-) mice were entrained to 12h:12h light:dark conditions for two weeks and sacrificed at 4 different time points (CT1, 7, 13, 19) on the second day after release into constant darkness conditions. Total RNA was isolated from epididymal white adipose tissue biopsies and subjected to microarray hybridization.

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL16570
24 Samples

Download data: CEL

Series

Accession:: GSE81532

ID:: 200081532

Select item 20000375111.

Circadian rhythm in clock mutants

(Submitter supplied) One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into DD (CT18), tissues from 5 (skeletal muscle) or 10 (liver or SCN) wildtype mice were collected every 4 hours for 48 hours, for a total of 12 timepoints. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1073
76 Samples

Download data: CEL

Series

Accession:: GSE3751

ID:: 200003751

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000374812.

Circadian liver_wt and Clock mutants

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1073
38 Samples

Download data: CEL

Series

Accession:: GSE3748

ID:: 200003748

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000374613.

Circadian skeletal muscle_wt and Clock mutants

(Submitter supplied) One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into DD (CT18), the left leg muscle from 5 wildtype mice, and the right leg muscle from the same wildtype mice were collected every 4 hours for 48 hours, for a total of 12 timepoints. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL1073
38 Samples

Download data: CEL

Series

Accession:: GSE3746

ID:: 200003746

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000056414.

Liver treatments Con, Veh, Dex

(Submitter supplied) Mouse liver RNA was extracted using Trizol (Invitrogen) and Qiagen RNeasy kits. RNA was checked with an Agilent Bioanalyzer for evidence of sub-genomic DNA and degradation. Targets were produced using standard Affymetrix protocols. Each sample represents data from a single mouse liver. Keywords: other

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL81
27 Samples

Download data

Series

Accession:: GSE564

ID:: 200000564

Select item 20002862215.

Expression data of mouse fetal liver during embryonic day 18 and 19

(Submitter supplied) The oscillation status of the circadian clock during late gestation is not clear. To gain a better understanding on the oscillation state of the clock and possible influences by maternal cues, we performed transcriptome analyses on the fetal liver tissue during late gestation. Fetal liver transcriptome data were analyzed and compared to adult mouse data in the public database: GSE11923 and GSE13093 (only samples GSM327130 to GSM327141). more...

Organism:: Mus musculus

Type:: Expression profiling by array; Third-party reanalysis

Platform:: GPL8321
24 Samples

Download data: CEL, TXT

Series

Accession:: GSE28622

ID:: 200028622

PubMed Full text in PMC Similar studies

Select item 20022403816.

Genome-wide RNAseq of hippocampi from single time point (2 hours post 0.75 mg/mL corticosterone injection) in adrenalectomized rats

(Submitter supplied) Disrupted circadian activity is associated with many neuropsychiatric disorders. A major coordinator of circadian biological systems is adrenal glucocorticoid secretion which exhibits a pronounced pre-awakening peak that regulates metabolic, immune, and cardiovascular processes, as well as mood and cognitive function. Loss of this circadian rhythm during corticosteroid therapy is often associated with memory impairment. more...