Similar studies for GEO DataSets (Select 2052) - GEO DataSets

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Items: 20

Select item 20521.

Endometrium throughout the menstrual cycle

Analysis of the normal endometrium at distinct phases of the menstrual cycle. Results provide insight into whether molecular profiles of the endometrium can distinguish the different phases of the menstrual cycle.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 5 other sets

Platform:: GPL570
Series:: GSE4888
27 Samples

Download data: CEL

DataSet

Accession:: GDS2052

ID:: 2052

Select item 2000048882.

Molecular phenotyping of human endometrium

(Submitter supplied) To examine the possibility that biochemical or molecular signatures of endometrium may prove to be more useful, we have investigated whole genome molecular phenotyping (54,600 genes/ESTs) of this tissue sampled across the cycle in 28 normo-ovulatory women, using high-density oligonucleotide microarrays. The results demonstrate that endometrial samples obtained by two different sampling techniques (biopsy and curetting hysterectomy specimens) from subjects who are as normal as possible in a human study and 4 including those with unknown histology, can be classified by their molecular signatures and correspond to known phases of the menstrual cycle with identical results using two independent analytical methods. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2052
Platform:: GPL570
27 Samples

Download data: CEL

Series

Accession:: GSE4888

ID:: 200004888

Select item 2000004033.

cAMP-induced differentiation of endometrial stromal cells

(Submitter supplied) Timecourse of cAMP-induced decidualization of endometrial stromal cells. Keywords: time-course

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8300
12 Samples

Download data

Series

Accession:: GSE403

ID:: 200000403

Select item 2000860034.

Identification of genes that play a role in menstrual breakdown and repair

(Submitter supplied) We examined the molecular profile of human endometrium on days 2, 3 and 4 of menstruation to identify genes and pathways that play a role in the menstrual process. Endometrial samples were collected by Pipelle biopsy on days 2 (n=9), 3 (n=9) or 4 (n=6) of menstruation and arrayed. We identified key gene pathways involved in menstruation and identified a number of genes not previously associated with the process (Paiva et al. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL22366
24 Samples

Download data: TSV

Series

Accession:: GSE86003

ID:: 200086003

Select item 2000390435.

Global gene expression changes during the estrous cycle in equine endometrium

(Submitter supplied) The equine endometrium exhibits characteristic morphological and functional changes during the estrous cycle controlled by the interplay of progesterone and estradiol. A microarray analysis of endometrial tissue samples derived from 5 time points of the estrous cycle (D0, D3, D8, D12, and D16) was performed to study the dynamics of endometrial gene expression. Endometrial biopsies were collected from five mares (Bavarian Warmblood) at the respective time points. more...

Organism:: Equus caballus

Type:: Expression profiling by array

Platform:: GPL15189
25 Samples

Download data: TXT

Series

Accession:: GSE39043

ID:: 200039043

Select item 2000165326.

Endometrial gene expression analysis at the time of embryo implantation in women with unexplained infertility

(Submitter supplied) The aim of this study was to investigate the endometrial gene expression profile in women with unexplained infertility in comparison to fertile controls at the time of embryo implantation in order to find potential informative markers of uterine receptivity, and further, to identify the molecular mechanisms related to infertility.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL4133
9 Samples

Download data: GPR

Series

Accession:: GSE16532

ID:: 200016532

Select item 2000210467.

Identification of differentially expressed genes in equine endometrium at day 8 and 12 of pregnancy

(Submitter supplied) In order to systematically analyze the maternal, i.e. the endometrial, changes in the equine endometrium underlying the complex embryo-maternal dialogue during early pregnancy, a transcriptome study of endometrium samples from five mares at day 8 and six mares at day 12 of early pregnancy and the corresponding non-pregnant stage was performed.

Organism:: Equus caballus

Type:: Expression profiling by array

Platform:: GPL10248
22 Samples

Download data: TXT

Series

Accession:: GSE21046

ID:: 200021046

Select item 2001066028.

Expression profile of early and mid-secretory human endometrium revealed by RNA-seq: a paired-sample cohort study

(Submitter supplied) Inner uterine lining or endometrium is a unique constantly self-renewed adult tissue that is vital for embryo implantation. As the footrace for universal endometrial receptivity markers continues, RNA-seq remains the most powerful tool for transcriptomic marker discovery. In this study, we aimed to elucidate endometrial maturation mechanisms at transcriptomic level and identify novel robust biomarker candidates for endometrial receptivity in a multicentre study. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
70 Samples

Download data: CSV, TSV

Series

Accession:: GSE106602

ID:: 200106602

Select item 2000793679.

Differential gene expression profiling of endometrium during the mid-luteal phase of the estrous cycle between repeat breeder and normal fertile cows

(Submitter supplied) We investigated differential gene expression profiles of endometrium during the mid-luteal phase of the estrous cycle between repeat breeding (RB) and normally fertilized cows using microarray analysis. Caruncular (CAR) and intercaruncular (ICAR) endometrium of both ipsilateral and contralateral uterine horns to the corpus luteum were collected from RB (inseminated at least three times but not pregnant) and normally fertile cows on Day 15 of the estrous cycle. more...

Organism:: Bos taurus

Type:: Expression profiling by array

Platform:: GPL19801
32 Samples

Download data: TXT

Series

Accession:: GSE79367

ID:: 200079367

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20000636410.

Gene Profiling of Endometrium Reveals Progesterone Resistance and Candidate Genetic Loci in Women with Endometriosis

(Submitter supplied) The transition of regularly cycling endometrium from the proliferative or Estrogen-dominant phase of the menstrual cycle to the Progesterone-dominant Early and Mid Secretory phases requires wide-spread changes in gene expression that shift the endometrium from a proliferative capacity to a differentiated 'decidual' phenotype in preparation for implantation. This process appears delayed in women with severe endometriosis, suggestive of a progesterone resistant endometrium in this disease. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2737
Platform:: GPL570
37 Samples

Download data: CEL

Series

Accession:: GSE6364

ID:: 200006364

Select item 273711.

Endometriosis

Analysis of endometrial specimens from women with endometriosis. Endometrial gene expression examined at various phases of the menstrual cycle. Results provide insight into the molecular pathogenesis of endometriosis.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state, 3 other sets

Platform:: GPL570
Series:: GSE6364
37 Samples

Download data: CEL

DataSet

Accession:: GDS2737

ID:: 2737

Select item 20009716312.

Stromal fibroblasts exhibit a similar transcriptome to mesenchymal stem cells in the perimenopausal endometrium

(Submitter supplied) Mesenchymal stem cells (eMSC) from perimenopausal (PeriM) endometrium do not exhibit significantly different transcriptomes from their premenopausal (PreM) counterparts, but PeriM endometrial stromal fibroblasts (eSF) demonstrate altered pathway activation.We compared transcriptomes of PeriM and PreM eSF, investigated if eMSC persist in PeriM endometrium, and whether eMSC and eSF undergo changes as a result of the perimenopausal endocrine milieu.Endometrium was obtained from 9 PeriM and 9 PreM women. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL6244
33 Samples

Download data: CEL

Series

Accession:: GSE97163

ID:: 200097163

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007395013.

The influence of menstrual cycle and endometriosis on endometrial methylome

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
43 Samples

Download data: IDAT

Series

Accession:: GSE73950

ID:: 200073950

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007394914.

Endometrial methylome of patients without endometriosis

(Submitter supplied) Alterations in endometrial DNA methylation profile have been proposed as one potential mechanism initiating the development of endometriosis. However, the normal endometrial methylome is influenced by the cyclic hormonal changes and the menstrual cycle phase-dependent epigenetic signature should be considered when studying endometrial disorders. So far, no studies have been performed to evaluate the menstrual cycle influences and endometriosis-specific endometrial methylation pattern at the same time. more...

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
17 Samples

Download data: IDAT, TXT

Series

Accession:: GSE73949

ID:: 200073949

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20007394815.

Endometrial methylome of patients with endometriosis

Organism:: Homo sapiens

Type:: Methylation profiling by genome tiling array

Platform:: GPL13534
26 Samples

Download data: IDAT, TXT

Series

Accession:: GSE73948

ID:: 200073948

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20005198116.

Molecular Classification of Endometriosis and Disease Stage Using High-Dimensional Genomic Data

(Submitter supplied) Endometriosis, an estrogen-dependent, progesterone-resistant, inflammatory disorder affects 10% of reproductive-age women. It is diagnosed and staged at surgery, resulting in an 11-year latency from symptom onset to diagnosis, underscoring the need for less invasive, less expensive approaches. Since the uterine lining (endometrium) in women with endometriosis has altered molecular profiles, we tested whether molecular classification of this tissue can distinguish and stage disease. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL570
148 Samples

Download data: CEL

Series

Accession:: GSE51981

ID:: 200051981

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20012658117.

Characterizing the Human Menstrual Cycle from a gene co-expression perspective reveals the pregnant endometrium as a global transcriptionally derepressed state

(Submitter supplied) Background: a fundamental challenge for reproductive biology is to understand the menstrual cycle, specially the window of implantation, whose regulation and mechanistic remain incompletely understood in human reproductive physiology. Transcriptomics from a systems biology perspective provides a genomic framework to discover endometrial tissue specific regulation and behavior and its function in reproductive physiology. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL26199
529 Samples

Download data: GPR

Series

Accession:: GSE126581

ID:: 200126581

Select item 20008045518.

Transcriptional Profiling of Human Endocervical Tissues Reveals Distinct Gene Expression in the Follicular and Luteal Phases of the Menstrual Cycle

(Submitter supplied) The goal of this study was to identify genes differentially expressed in the follicular and luteal phases of the menstrual cycle in the human endocervix and to identify significantly represented biological pathways and processes. This was done in order to better understand mechanisms associated with hormonal regulation of endocervix function which has implications in susceptibility to infections.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL10558
12 Samples

Download data: IDAT, TXT

Series

Accession:: GSE80455

ID:: 200080455

Select item 20011197619.

Single cell RNA-seq analysis on human endometrium across the natural menstrual cycle

(Submitter supplied) To unbiasedly and systematically characterize endometrial transformation across the human menstrual cycle in preparation for embryo implantation, we analyzed the transcriptomic transformation of human endometrium at single cell resolution, dissecting multidimensional cellular heterogeneity of the tissue across the entire natural menstrual cycle.