GEO DataSets

(Submitter supplied) We report the results of treatment of embryonic limbs with bisphenol AF. RNA sequencing was performed to measure differential expression as a result of exposure to BPAF compared to DMSO treated control limbs.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

45 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

135 Samples

Download data

(Submitter supplied) We report the results of treatment of embryonic limbs with bisphenol S. RNA sequencing was performed to measure differential expression as a result of exposure to BPS compared to DMSO treated control limbs.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

45 Samples

Download data: TXT

(Submitter supplied) We report the results of treatment of embryonic limbs with bisphenols A. RNA sequencing was performed to measure differential expression as a result of exposure compared to DMSO treated control limbs.

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

45 Samples

Download data: TXT

(Submitter supplied) Whole genome expression data on transcriptome of human osteosarcoma (HOS) cells induced by bisfenol A (BPA), S (BPAS) and AF (BPAF) after short- (8 hours) and long-term (3 months) exposure at human-relevant (10 nM) concentrations.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL10558

24 Samples

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(Submitter supplied) We studied alterations in gene expression profiles of the MCF7 human breast cancer cells caused by bisphenol A, bisphenol AF and glyphosate using Illumina RNA sequencing platform.

Organism:

Homo sapiens

Type:

Expression profiling by high throughput sequencing

Platform:

GPL16791

15 Samples

Download data: TXT

(Submitter supplied) Plasticizers with estrogenic activity, such as bisphenol A (BPA), have been reported to have potential adverse health effects in humans, especially in fetal and infant stages. Due to mounting evidence and public pressure BPA is being phased out by the plastics manufacturing industry and is being replaced by other bisphenol variants in “BPA-free” products. We have compared estrogenic activity of 7 bisphenol analogues (BPA; bisphenol S, BPS; bisphenol F, BPF; bisphenol AP, BPAP; bisphenol AF, BPAF; bisphenol Z, BPZ; bisphenol B, BPB) in human breast cancer cell lines. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL17586

33 Samples

Download data: CEL

(Submitter supplied) Purpose: the goal of this study is to determine the changes in gene expression during EB differentiation after BPA, BPF and BPS treatments, as indications of potential developmental toxicity. Methods: Transcriptomics profiling for EB samples treated with 100 nM BPA, BPF, BPS or DMSO control at different time points were generated by RNA-seq, using a BGISEQ-500 platform. Reads were filtered and aligned to the reference genome with Bowtie2. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL23479

32 Samples

Download data: TXT

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Homo sapiens

Type:

Expression profiling by array; Non-coding RNA profiling by array

Platforms:

GPL16699 GPL19730

123 Samples

Download data: TXT

(Submitter supplied) Bisphenols F (BPF) and S (BPS) are BPA structural analogs used in many marketed products as a replacement for BPA. Since sparse toxicological data are available yet for these bisphenol substitutes, our objective was to comprehensively characterize bisphenols gene targets in a human primary adipocyte model, using chronic exposure at two concentrations: a “low-dose” similar to the dose usually encountered in human biological fluids and a higher dose.

Organism:

Homo sapiens

Type:

Non-coding RNA profiling by array

Platform:

GPL19730

63 Samples

Download data: TXT

(Submitter supplied) Bisphenols F (BPF) and S (BPS) are BPA structural analogs used in many marketed products as a replacement for BPA. Since sparse toxicological data are available yet for these bisphenol substitutes, our objective was to comprehensively characterize bisphenols gene targets in a human primary adipocyte model, using chronic exposure at two concentrations: a “low-dose” similar to the dose usually encountered in human biological fluids and a higher dose.

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL16699

60 Samples

Download data: TXT

(Submitter supplied) Bisphenol A (BPA) analogs, bisphenol B (BPB) and bisphenol AF (BPAF) have been widely detected in the environment and human products with increasing frequency. However, uterine health risks caused by BPBBisphenol A (BPA) analogs, bisphenol B (BPB) and bisphenol AF (BPAF) have been widely detected in the environment and human products with increasing frequency. However, uterine health risks caused by BPB and BPAF exposure need to be further elucidated. more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL17021

9 Samples

Download data: TXT

(Submitter supplied) Organophosphate esters (OPEs) are used widely as flame retardants and plasticizers but much remains unknown about their potential toxicity. Previously, we reported that four individual OPEs suppress endochondral ossification in murine limb bud cultures. However, real-life exposure is to complex OPE mixtures. In the present study, we tested the hypothesis that a Canadian household dust-based OPE mixture will affect endochondral ossification in gestation day 13 CD1 mouse embryo limb buds expressing fluorescent markers for the major cell populations involved in the process: COL2A1-ECFP (proliferative chondrocytes), COL10A1-mCherry (hypertrophic chondrocytes), and COL1A1-YFP (osteoblasts). more...

Organism:

Mus musculus

Type:

Expression profiling by high throughput sequencing

Platform:

GPL24247

8 Samples

Download data: TXT

(Submitter supplied) In this work we use an in vitro model to characterize the transcriptomic effect of low-concentration exposure to bisphenol A, S or F in the two main stages of the disease: androgen dependency (LNCaP) and resistance (PC-3). using Affimetrix Clariom D technology

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL23126

24 Samples

Download data: CEL, CHP