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Status |
Public on May 12, 2023 |
Title |
Bisphenol B and bisphenol AF exposure enhances uterine diseases risks in mouse |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Bisphenol A (BPA) analogs, bisphenol B (BPB) and bisphenol AF (BPAF) have been widely detected in the environment and human products with increasing frequency. However, uterine health risks caused by BPBBisphenol A (BPA) analogs, bisphenol B (BPB) and bisphenol AF (BPAF) have been widely detected in the environment and human products with increasing frequency. However, uterine health risks caused by BPB and BPAF exposure need to be further elucidated. The study aimed to explore whether BPB or BPAF exposure will induce adverse outcomes in uterus. We then performed gene expression profiling using data obtained from mouse uterus exposed to BPB and BPAF at 28 days.
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Overall design |
Comparative gene expression profiling analysis of RNA-seq data from mouse uterus (control group, 28-day BPB exposure group, and 28-day BPAF exposure group).
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Contributor(s) |
Wu X, Yang X, Tian Y, Xu P, Yue H, Sang N |
Citation(s) |
36881955 |
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Submission date |
Jan 22, 2023 |
Last update date |
May 13, 2023 |
Contact name |
Xiaoyun Wu |
E-mail(s) |
202023902017@email.sxu.edu.cn
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Organization name |
Shanxi University
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Street address |
Wucheng Road 92, Xiaodian District
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City |
Taiyuan |
State/province |
Shanxi |
ZIP/Postal code |
030006 |
Country |
China |
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Platforms (1) |
GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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Samples (9)
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GSM6956622 |
mouse uterus,BPB, rep1 |
GSM6956623 |
mouse uterus,BPB, rep2 |
GSM6956624 |
mouse uterus,BPB, rep3 |
GSM6956625 |
mouse uterus, BPAF, rep1 |
GSM6956626 |
mouse uterus, BPAF, rep2 |
GSM6956627 |
mouse uterus, BPAF, rep3 |
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Relations |
BioProject |
PRJNA926360 |
Supplementary file |
Size |
Download |
File type/resource |
GSE223464_RAW.tar |
2.3 Mb |
(http)(custom) |
TAR (of TXT) |
SRA Run Selector |
Raw data are available in SRA |
Processed data provided as supplementary file |
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