Similar studies for GEO DataSets (Select 200115770) - GEO DataSets

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Items: 12

Select item 2001157701.

A network of transcriptome modules demonstrates mechanistic pathways of both virus induced and non-viral asthma exacerbations in children [nasal]

(Submitter supplied) We leverage a systems-scale network analysis approach to demonstrate repertoires of cellular transcriptional pathways underlying loss of asthma control, and show how these pathways differ in viral associated and non-viral exacerbations.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
523 Samples

Download data: TXT

Series

Accession:: GSE115770

ID:: 200115770

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2001158242.

A network of transcriptome modules demonstrates mechanistic pathways of both virus induced and non-viral asthma exacerbations in children

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
1034 Samples

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Series

Accession:: GSE115824

ID:: 200115824

PubMed Full text in PMC Similar studies

Select item 2001158233.

A network of transcriptome modules demonstrates mechanistic pathways of both virus induced and non-viral asthma exacerbations in children [blood]

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
511 Samples

Download data: TXT

Series

Accession:: GSE115823

ID:: 200115823

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000303264.

Virus-induced inflammatory gene networks underlying asthma exacerbations in vivo

(Submitter supplied) Global patterns of gene expression was profiled in nasal lavage samples obtained from asthmatic children during an acute Picornavirus-induced exacerbation and 7-14 days later. Gene coexpression network analysis and prior knowledge was employed to reconstruct the wiring diagram of the underlying gene networks.

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4424
Platform:: GPL6244
32 Samples

Download data: CEL

Series

Accession:: GSE30326

ID:: 200030326

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Select item 44245.

Acute Picornavirus-induced exacerbation in asthmatic children: nasal lavage cells

Analysis of paired nasal lavage samples obtained from asthmatic children during an acute Picornavirus-induced asthma exacerbation in vivo and 7-14 days later. Severe episodes can be life-threatening. Results provide insight into molecular mechanisms underlying virus-induced asthma exacerbations.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 16 individual, 2 protocol sets

Platform:: GPL6244
Series:: GSE30326
32 Samples

Download data: CEL

DataSet

Accession:: GDS4424

ID:: 4424

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 2000160326.

Gene expression data from severe asthmatic children: PBMC profiles during acute exacerbation versus convalescence

(Submitter supplied) Severe asthma exacerbations in children requiring hospitalisation are typically associated with viral infection, and occur almost exclusively amongst atopics, but the significance of these comorbidities is unknown. We hypothesised that underlying interactions between immunoinflammatory pathways related to responses to aeroallergen and virus are involved, and that evidence of these interactions is detectable in circulating cells during exacerbations. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS3615
Platform:: GPL570
10 Samples

Download data: CEL

Series

Accession:: GSE16032

ID:: 200016032

Select item 36157.

Asthma exacerbation and convalescent phases: peripheral blood mononuclear cells

Analysis of peripheral blood mononuclear cells of children with acute asthma during exacerbation and at subsequent convalescence. Severe asthma exacerbations in children are associated with viral infection and occur among atopics. Results provide insight into the significance of these comorbidities.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 disease state sets

Platform:: GPL570
Series:: GSE16032
10 Samples

Download data: CEL

DataSet

Accession:: GDS3615

ID:: 3615

Select item 2001031668.

Gene expression profiling of nasal swabs samples from children with asthma or wheezing exacerbations.

(Submitter supplied) Nasal swab specimens were collected from children who presented to the emergency department with an acute exacerbation of asthma or wheeze. Samples were also collected from control subjects. Convalescent/quiescent samples were collected from children who were followed-up at least 6 weeks after an acute exacerbation of asthma or wheeze. Gene expression was profiled on microarrays.

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL23961
106 Samples

Download data: CEL

Series

Accession:: GSE103166

ID:: 200103166

Select item 2000193019.

Gene Expression Patterns in Peripheral Blood Mononuclear Cells Associated with Asthma Exacerbation Attack

(Submitter supplied) A large, prospective, non-interventional study was designed to study gene expression changes in peripheral blood mononuclear cells (PBMCs) associated with asthma exacerbations over the course of a year. PBMC samples were collected from subjects at the time of the study visits defined as 1) Quiet: during stable disease at 3 month intervals, 2) Exacerbation: during a 14 day period of deteriorating asthma and 3) Follow-up: within 14 days after cessation of an exacerbation. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL96
685 Samples

Download data: CEL

Series

Accession:: GSE19301

ID:: 200019301

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20021115810.

Transcriptome networks identify susceptibility to frequent asthma exacerbations

(Submitter supplied) To investigate mechanisms underlying frequent asthma exacerbation, we profiled the nasal transcriptome of both frequent and non-frequent asthma exacerbators.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL15433
139 Samples

Download data: CSV

Series

Accession:: GSE211158

ID:: 200211158

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 20009653011.

LPS binding protein and activation signatures are upregulated during asthma exacerbations in children

(Submitter supplied) Asthma exacerbations in children are associated with respiratory viral infection and atopy, resulting in systemic immune activation and infiltration of immune cells into the airways. The gene networks driving the immune activation and subsequent migration of immune cells into the airways remains incompletely understood. Cellular and molecular profiling of PBMC was employed on paired samples obtained from atopic asthmatic children (n = 19) during acute virus-associated exacerbations and later during convalescence. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL16791
76 Samples

Download data: TXT

Series

Accession:: GSE96530

ID:: 200096530

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 20006114112.

Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus

(Submitter supplied) We report the application of RNA sequencing technology for high-throughput profiling of gene expression responses to human rhinovirus infection at 24 hours in air-liquid interface human airway epithelial cell cultures derived from 6 asthmatic and 6 non-asthmatic donors. RNA-seq analysis identified sets of genes associated with asthma specific viral responses. These genes are related to inflammatory pathways, epithelial remodeling and cilium assembly and function, including those described previously (e.g. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL11154
24 Samples

Download data: TXT

Series

Accession:: GSE61141

ID:: 200061141

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

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Similar studies for GEO DataSets (Select 200115770) (12)
GEO DataSets
MAG: Gammaproteobacteria bacterium RIFCSPLOWO2_01_FULL_47_190 rifcsplowo2_01_sca...
MAG: Gammaproteobacteria bacterium RIFCSPLOWO2_01_FULL_47_190 rifcsplowo2_01_scaffold_15416, whole genome shotgun sequence
gi|1085177928|gb|MGYK01000018.1||gn :MGYK01|rifcsplowo2_01_scaffold_15416

Nucleotide
MAG: Gammaproteobacteria bacterium RIFCSPLOWO2_01_FULL_47_190 rifcsplowo2_01_sca...
MAG: Gammaproteobacteria bacterium RIFCSPLOWO2_01_FULL_47_190 rifcsplowo2_01_scaffold_14408, whole genome shotgun sequence
gi|1085177969|gb|MGYK01000016.1||gn :MGYK01|rifcsplowo2_01_scaffold_14408

Nucleotide

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