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Links from GEO DataSets

Items: 20

1.

In vivo functional analysis of L-rhamnose metabolic pathway in Aspergillus niger: a tool to identify the potential inducer of RhaR

(Submitter supplied) The genes of the non-phosphorylative L-rhamnose catabolic pathway have been identified for several yeast species. In Pichia stipitis, all L-rhamnose pathway genes are organized in a cluster, which is conserved in Aspergillus niger, except for the lra-4 ortholog (lraD). The A. niger cluster also contains the gene encoding the L-rhamnose responsive transcription factor (RhaR) that has been shown to control the expression of genes involved in L-rhamnose release and catabolism. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
10 Samples
Download data: TXT
Series
Accession:
GSE99865
ID:
200099865
2.

Aspergillus niger RhaR, a regulator involved in L-rhamnose release and catabolism

(Submitter supplied) The genome of the filamentous fungus Aspergillus niger is rich in genes encoding pectinases, a broad class of enzymes that have been extensively studied due to their use in industrial applications. The sequencing of the A. niger genome provided more knowledge concerning the individual pectinolytic genes, but relatively little is still known about the regulatory genes involved in pectin degradation. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
4 Samples
Download data: CEL
Series
Accession:
GSE51023
ID:
200051023
3.

Evidence for inducer function of 2-keto-3-deoxy-L-galactonate in D-galacturonic acid induced gene expression in Aspergillus niger

(Submitter supplied) In Aspergillus niger, the enzymes encoded by gaaA, gaaB, gaaC and gaaD catabolize D-galacturonic acid (GA) consecutively into L-galactonate, 2-keto-3-deoxy-L-galactonate, pyruvate and L-glyceraldehyde, and glycerol. We show here that deletion of gaaB or gaaC results in severely impaired growth on GA and accumulation of pathway intermediates L-galactonate and 2-keto-3-deoxy-L-galactonate, respectively. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
2 Samples
Download data: XLS
Series
Accession:
GSE95776
ID:
200095776
4.

Expression analysis of L-rhamnose catabolism in the yeast Scheffersomyces stipitis

(Submitter supplied) In Scheffersomyces stipitis and related fungal species the genes for L-rhamnose catabolism RHA1, LRA2, LRA3 and LRA4 but not LADH are clustered. We find that located next to the cluster is a transcription factor, TRC1, which is conserved among related species.Our transcriptome analysis shows that all the catabolic genes and all genes of the cluster are up-regulated on L-rhamnose. Among the genes that were also up-regulated on L-rhamnose were two transcription factors including the TRC1. more...
Organism:
Scheffersomyces stipitis CBS 6054
Type:
Expression profiling by array
Platform:
GPL13403
6 Samples
Download data: PAIR
Series
Accession:
GSE28557
ID:
200028557
5.

Scheffersomyces_stipitis_CBS 6054_385k_array

(Submitter supplied) NimbleGen design name 2007-01-31_TJ_Picst3 Nimblegen design id 5183. Array contains 13 60-mer probes for each open reading frame. Each probe was replicated five times on the chip. The design includes random GC and other control probes. The Platform data table reflects a condensed representation of the expression array's replicate (SEQ_ID) features. The .ndf and .ngd files are linked below as supplementary files. more...
Organism:
Scheffersomyces stipitis CBS 6054
1 Series
6 Samples
Download data: NDF, NGD
Platform
Accession:
GPL13403
ID:
100013403
6.

Combinatorial control of gene expression in Aspergillus niger grown on sugar beet pectin

(Submitter supplied) The aim of this study was to better understand the contribution of the transcriptional activators GaaR, RhaR and AraR in regulation of pectin degradation in A. niger.
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
32 Samples
Download data: TXT
Series
Accession:
GSE97974
ID:
200097974
7.

Expression-based clustering of CAZyme-encoding genes of Aspergillus niger

(Submitter supplied) The Aspergillus niger genome contains a large repertoire of genes encoding carbohydrate active enzymes (CAZymes) that are targeted to plant polysaccharide degradation enabling A. niger to grow on a wide range of plant biomass substrates. Which genes need to be activated in certain environmental conditions depends on the composition of the available substrate. Previous studies have demonstrated the involvement of a number of transcriptional regulators in plant biomass degradation and have identified sets of target genes for each regulator. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
59 Samples
Download data: CEL
Series
Accession:
GSE98572
ID:
200098572
8.

Aspergillus niger exposed to combinations of carbon source, nitrogen source, nitrogen concentration, and culture pH

(Submitter supplied) Microarray analysis of Aspergillus niger under conditions with differing combinations of carbon source, nitrogen source, nitrogen concentration, and culture pH Fermentor cultures were grown in minimal medium (MM) at a constant temperature of 30 ± 0.5 ºC and with differing combinations of carbon source (either 277.5 mM glucose or 333.0 mM xylose), nitrogen source (NH4Cl or NaNO3) and nitrogen concentration (4x: 282.4 mM; 8x: 564.8 mM), and pH (pH4 or pH5) of the medium (M. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
20 Samples
Download data: CEL
Series
Accession:
GSE17329
ID:
200017329
9.

The transcriptional response of bioreactor-grown Aspergillus niger cultures towards three oils

(Submitter supplied) The industrially important fungus Aspergillus niger feeds naturally on decomposing plant material, for which it is equipped with a range of enzyme systems. A significant proportion of plant material are lipids that might be available either as for energy storage or as membrane building blocks. With 63 potential lipase-encoding genes in its genome, A. niger has the tools to degrade these extracellular lipids. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
16 Samples
Download data: CEL
Series
Accession:
GSE14285
ID:
200014285
10.

Determination of variability of fermentor-grown Aspergillus niger

(Submitter supplied) Knowledge of the biological and technical variation for fermentor-grown Aspergillus niger cultures is needed to design DNA microarray experiments properly. We cultured A. niger in batch-operated fermentor vessels and induced with D-xylose. Transcript profiles were followed in detail by qPCR for 8 genes. A variance components analysis was performed on these data to determine the origin and magnitude of variation within each process step for this experiment. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
7 Samples
Download data: CEL
Series
Accession:
GSE11405
ID:
200011405
11.

The galactose regulator GalX regulates the D-galactose oxido-reductive pathway in Aspergillus niger.

(Submitter supplied) Galactose catabolism in Aspergillus nidulans is regulated by at least two regulators, GalR and GalX. In Aspergillus niger only GalX is present, and its role in D-galactose catabolism in this fungus was investigated. Phenotypic and gene expression analysis of a wild type and a galX disruptant revealed that GalX does not substitute for the absence of GalR in A. niger, it regulates the D-galactose oxido-reductive pathway, but not the Leloir pathway. more...
Organism:
Aspergillus niger CBS 513.88; Aspergillus niger
Type:
Expression profiling by array
Platform:
GPL6758
4 Samples
Download data: CEL
Series
Accession:
GSE40219
ID:
200040219
12.

The transcriptional activator GaaR of Aspergillus niger is required for release and utilization of D-galacturonic acid from pectin

(Submitter supplied) We identified the D-galacturonic acid (GA) responsive transcriptional activator GaaR of the saprotrophic fungus Aspergillus niger, which was found to be essential for growth on GA and polygalacturonic acid (PGA). Growth of the ΔgaaR strain was reduced on complex pectins. Genome-wide expression analysis showed that GaaR is required for the expression of genes necessary to release GA from PGA and more complex pectins, to transport GA into the cell and to induce the GA-catabolic pathway. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
16 Samples
Download data: TXT
Series
Accession:
GSE80227
ID:
200080227
13.

The FlbA-regulated transcription factor FusR of Aspergillus niger is involved in production of fumonisin

(Submitter supplied) Colonies of Aspergillus niger secrete proteins throughout the colony except for the sporulating zone. Inactivation of flbA results in colonies that are unable to reproduce asexually and that secrete proteins throughout the mycelium. In addition, the ΔflbA strain shows cell lysis and has thinner cell walls. This pleiotropic phenotype is associated with differential expression of 38 transcription factor genes. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21090
4 Samples
Download data: DIFF
Series
Accession:
GSE93990
ID:
200093990
14.

Comparative transcriptomics of Aspergillus niger when deleted or overexpressed for the putative transcription factors MjkA, MjkB and the histon deactelyase HdaX

(Submitter supplied) Purpose: Expression profiling of two ORFs encoding putative transcription factors: An07g07370 (TF1/MjkA) and An12g07690 (TF2/MjkB), and a histone deacetylase (An09g06520, HdaX) under carbon-limited batch cultivations (biological duplicate runs) in Aspergillus niger. Methods: Single deletion strains for TF1, TF2 and HD, respectively, (ii) a double deletion strain for TF1 and TF2, and (iii) individual conditional overexpression mutants for TF1, TF2 and HD using the Tet-on system were analysed. more...
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25519
28 Samples
Download data: TXT
Series
Accession:
GSE119311
ID:
200119311
15.

A novel L-arabinose-responsive regulator found in the rice-blast fungus Pyricularia oryzae (Magnaporthe oryzae)

(Submitter supplied) In this study we identified the L-arabinose-responsive regulator of Pyricularia oryzae that regulates L-arabinose release and catabolism. Previously we identified the Zn2Cys6 transcription factor (TF) AraR that has this role in the Trichocomaceae family (Eurotiales), but is absent in other fungi. Candidate Zn2Cys6 TF genes were selected according to their transcript profiles on L-arabinose. Deletion mutants of these genes were screened for their growth phenotype on L-arabinose. more...
Organism:
Pyricularia oryzae
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16530
6 Samples
Download data: XLS
Series
Accession:
GSE74916
ID:
200074916
16.

The transcriptional repressor TupA in Aspergillus niger is involved in controlling gene expression related to cell wall biosynthesis, development, and nitrogen source availability

(Submitter supplied) The Tup1-Cyc8 (Ssn6) complex is a well characterized and conserved general transcriptional repressor complex in eukaryotic cells. Here, we report the identification of the Tup1 (TupA) homolog in the filamentous fungus Aspergillus niger in a genetic screen for mutants with a constitutive expression of the agsA gene. The agsA gene encodes a putative alpha-glucan synthase, which is induced in response to cell wall stress in A niger. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
4 Samples
Download data: CEL
Series
Accession:
GSE50523
ID:
200050523
17.

Transcriptome study on Aspergillus niger during citrate fermentation.

(Submitter supplied) We report the genes regulated during citrate fermentation.
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21090
6 Samples
Download data: FASTA, TXT
Series
Accession:
GSE74544
ID:
200074544
18.

Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger

(Submitter supplied) Background: HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous hacA gene of an Aspergillus niger strain with a gene encoding a constitutively active form of the HacA transcription factor (HacACA). The impact of constitutive HacA activity during exponential growth was explored in bioreactor controlled cultures using transcriptomic analysis to identify affected genes and processes. more...
Organism:
Aspergillus niger; Aspergillus niger CBS 513.88
Type:
Expression profiling by array
Platform:
GPL6758
12 Samples
Download data: CEL
Series
Accession:
GSE39070
ID:
200039070
19.

Identification of three enzymes of the vanillin and vanillic acid metabolic pathway in the filamentous fungi Aspergillus niger

(Submitter supplied) The aim of this study was to find candidate genes in A. niger involved in the vanillic acid metabolic pathway.
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL25519
8 Samples
Download data: TXT
Series
Accession:
GSE154865
ID:
200154865
20.

Evolutionary adaptation of Aspergillus niger for increased ferulic acid tolerance

(Submitter supplied) The aim of this study was to find candidate genes in A. niger involved in the increase tolerance against ferulic acid in A. niger Fa6
Organism:
Aspergillus niger
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21721
8 Samples
Download data: TXT
Series
Accession:
GSE135001
ID:
200135001
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