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Links from GEO DataSets

Items: 17

1.

Cumulus cell gene expression associated with pre-ovulatory acquisition of developmental competence in bovine oocytes

(Submitter supplied) This study investigated the cumulus cell (CC) transcriptomic changes during the oocyte developmental competence acquisition period.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
18 Samples
Download data: TXT
Series
Accession:
GSE79760
ID:
200079760
2.

Bovine cumulus cells transcriptome in relation with oocyte chromatin configuration of the germinal vesicle

(Submitter supplied) Gene expression analysis in cc from COCs with different chromatin configuration (GV0-3)
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
12 Samples
Download data: TXT
Series
Accession:
GSE79886
ID:
200079886
3.

Bovine adult versus prepubertal cumulus cells

(Submitter supplied) The present study was undertaken to discover molecular markers in bovine cumulus cells predictive of oocyte competence and elucidate their functional significance. Differences in RNA transcript abundance in cumulus cells harvested from oocytes of adult versus prepubertal animals (model of poor oocyte quality) were identified by microarray analysis. Four genes of interest encoding for the lysosomal cysteine proteinases cathepsin B, S, K and Z and displaying greater transcript abundance in cumulus cells surrounding oocytes harvested from prepubertal animals were chosen for further investigation. more...
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL325
8 Samples
Download data: TXT
Series
Accession:
GSE10819
ID:
200010819
4.

Next Generation Sequencing of Oocyte and Associated Cumulus Cells Pools from Preovualtory Follicles in Bovine

(Submitter supplied) Purpose: Preovualtory follicle diameter influences embryo quality in beef cattle that rely on a gonadotropin releasing hormone (GnRH) injection to induce the preovualtory gonadotropin surge and subsequent ovualtion. The goals of this study are to compare transcriptome profiles of pools of four oocytes or associated cumulus cells collected from small (≤11.7mm) and large follicles (≥12.7 mm) exposed to a GnRH-induced gonadotropin surge and follicles (11.7-14.0 mm) exposed to an endogenous gonadotropin surge (spontaneous follicles). more...
Organism:
Bos taurus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL15749
33 Samples
Download data: TXT
Series
Accession:
GSE176344
ID:
200176344
5.

Granulosa cell differentiation in vivo and developmental competence of oocytes in the bovine model

(Submitter supplied) Transcriptional profiling of in vivo granulosa cells collected at 20h, 44h, 68h, and 92h of coasting in lactating cow (breed Holstein)
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
36 Samples
Download data: TXT
Series
Accession:
GSE40916
ID:
200040916
6.

Effect of adenosine on the gene expression profile of cumulus cells in vitro cultured as cumulus-oocyte complexes for 6 h

(Submitter supplied) Changes in gene expression induced by adenosine treatment in cumulus cells using Agilent EmbryoGENE microarray slides. Bovine cumulus-oocyte complexes in vitro-cultured for 6 h using adenosine and compared to non-treated (control). After culture, COC were were washed and cumulus cells were used for microarray analysis
Organism:
Bos taurus; Bos indicus
Type:
Expression profiling by array
Platform:
GPL13226
8 Samples
Download data: TXT
Series
Accession:
GSE119804
ID:
200119804
7.

Effect of FSH on the gene expression profile of cumulus cells in vitro cultured as cumulus-oocyte complexes in presence of adenosine for 6 h

(Submitter supplied) Changes in gene expression induced by FSH in cumulus cells treated with adenosine using Agilent EmbryoGENE microarray slides. Bovine cumulus-oocyte complexes in vitro-cultured for 6 h using adenosine. The effect of FSH was compared with control as non-treated cumulus-oocyte complexes. After culture, COC were were washed and cumulus cells were used for microarray analysis
Organism:
Bos indicus; Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
8 Samples
Download data: TXT
Series
Accession:
GSE119803
ID:
200119803
8.

Expression data from human cumulus cells isolated from oocytes at MI and MII stages in polycystic ovary syndrome (PCOS) patients

(Submitter supplied) Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder that is characterized by increased circulating androgen levels, anovulatory infertility, and frequently, insulin resistance and hyperinsulinemia.The abnormity of oocyte nuclear maturity is the main reason for anovulatory infertility and pregnancy loss in PCOS patients.The bidirectional exchanges between oocyte and contiguous CCs are important for oocyte competence acquisition, early embryonic development and CC expansion.Gene expression profiles of CCs has been suggested to predict embryo development and pregnancy outcome. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
6 Samples
Download data: CEL
Series
Accession:
GSE40400
ID:
200040400
9.

Gene expression analysis of pig cumulus-oocyte complexes stimulated in vitro with follicle stimulating hormone or epidermal growth factor-like peptides

(Submitter supplied) Background: The gonadotropin-induced resumption of oocyte meiosis in preovulatory follicles is preceded by expression of epidermal growth factor (EGF)-like peptides, amphiregulin (AREG) and epiregulin (EREG), in mural granulosa and cumulus cells. Both the gonadotropins and the EGF-like peptides possess the capacity to stimulate resumption of oocyte meiosis in vitro via activation of a broad signaling network in cumulus cells. more...
Organism:
Sus scrofa
Type:
Expression profiling by array
Platform:
GPL7435
9 Samples
Download data: TXT
Series
Accession:
GSE64858
ID:
200064858
10.

Effect of low dose docosahexaenoic acid (DHA) on bovine cumulus cells during in vitro maturation

(Submitter supplied) In order to decipher the pathways of DHA via cumulus cells (CC) surrounding an oocytes, microarray hybridization of cumulus cells after 4h IVM in the presence or absence of 1µM DHA was performed.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL21724
8 Samples
Download data: TXT
Series
Accession:
GSE94338
ID:
200094338
11.

Transcriptome analysis of FSH response in bovine cumulus cells

(Submitter supplied) Study the effect of recombinant human FSH supplementation in the in vitro maturation medium for an incubation of 6 hrs on the transcriptomics of bovine cumulus cells.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
6 Samples
Download data: TXT
Series
Accession:
GSE67970
ID:
200067970
12.

Transcriptome analysis of bovine cumulus cells during first 6 hrs of in vitro maturation

(Submitter supplied) Study the effect of in vitro maturation system on the transcriptomics of bovine cumulus cells during incubation of first 6 hrs.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL13226
6 Samples
Download data: TXT
Series
Accession:
GSE67969
ID:
200067969
13.

Contribution of molecular actors from somatic origin to oocyte developmental competence acquisition, lessons from evolution

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Oncorhynchus mykiss; Bos taurus; Xenopus laevis; Mus musculus
Type:
Expression profiling by array
4 related Platforms
75 Samples
Download data: TXT
Series
Accession:
GSE36617
ID:
200036617
14.

Transcriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the bovine ovarian follicles.

(Submitter supplied) Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 cumulus cells (CC) were sampled from immature calf oocytes, C1 samples from immature cow oocytes, and C2 samples from in vivo matured cow oocytes.
Organism:
Bos taurus
Type:
Expression profiling by array
Platform:
GPL9712
17 Samples
Download data: TXT
Series
Accession:
GSE36605
ID:
200036605
15.

Transcriptional profiling of cumulus cells differentiation throughout oocyte competence acquisition in the murine ovarian follicles.

(Submitter supplied) Cumulus cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were collected from immature, unexpanded cumulus-oocytes complexes (COC) from prepubertal (3-week-old) mice, C1 samples from immature, unexpanded cumulus-oocytes complexes (COC) from adult (8-week-old) and C2 samples from mature, expanded COCs obtained from the oviduct from 8-week-old mice after standard superovulation protocol.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
15 Samples
Download data: TXT
Series
Accession:
GSE36604
ID:
200036604
16.

Transcriptional profiling of somatic cells differentiation throughout oocyte competence acquisition in the xenopus ovarian follicles.

(Submitter supplied) Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were collected from immature stage IV follicles, C1 samples from immature stage VI follicles, and C2 samples from in vitro matured stage VI follicles.
Organism:
Xenopus laevis
Type:
Expression profiling by array
Platform:
GPL11258
15 Samples
Download data: TXT
Series
Accession:
GSE36603
ID:
200036603
17.

Transcriptional profiling of somatic cells differentiation throughout oocyte competence acquisition in rainbow trout ovarian follicles.

(Submitter supplied) Somatic cells surrounding the oocyte were sampled at the following stages: developmentally incompetent or poorly competent prophase I oocytes (NC1 oocytes), developmentally competent prophase I oocytes (C1 oocytes), and developmentally competent metaphase II oocytes (C2 oocytes). NC1 samples were collected from late vitellogenic females (LV), C1 samples from post-vitellogenic females (PV), and C2 samples from females undergoing meiotic maturation (Germinal Vesicle Breakdown)
Organism:
Oncorhynchus mykiss
Type:
Expression profiling by array
Platform:
GPL15258
28 Samples
Download data: TXT
Series
Accession:
GSE36602
ID:
200036602
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