U.S. flag

An official website of the United States government

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO DataSets

Items: 20

1.

Genome wide transcript and miRNAanalysis of invitro and in-vivo generated human cardiac samples

(Submitter supplied) We report the identification of miRNAs and transcripts that are regulated during human cardiac maturation.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
30 Samples
Download data: TSV
2.

Expression of miRNA in Embryonic Stem Cells-Derived Cardiomyocytes after coculture with Endothelial Cells

(Submitter supplied) To identify the miRNA that potentially promote the maturation of Embryonic Stem Cells-Derived Cardiomyocytes, we performed miRNA assay profiling to further know the miRNA expression that differentially expressed after coculture with endothelial cells To further know the miRNA expression that differentially expressed after coculture with endothelial cells, we performed miRNA assay profiling to identify the miRNA that potentially promote the maturation of Embryonic Stem Cells-Derived Cardiomyocytes
Organism:
Rattus norvegicus; Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by array
Platform:
GPL20571
3 Samples
Download data: GPR
Series
Accession:
GSE69927
ID:
200069927
3.

Gene expression profile of mouse embryonic stem cells derived cardiomyocytes following the knockdown of ErbB4

(Submitter supplied) To identify the potential target genes that were affected by the expression of ErbB4 in mouse embryonic stem cells-derived cardiomyocytes
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11202
4 Samples
Download data: TXT
Series
Accession:
GSE69897
ID:
200069897
4.

Transcriptome-guided functional analyses reveal novel biological properties and regulatory heirarchy of human embryonic stem cell derived ventricular cardiomyocytes.

(Submitter supplied) Profiling global gene expression of undifferentiated human embryonic stem cells, artificially derived cardiomyocytes, fetal ventricular cardiomyocytes, and adult ventricular cardiomyocytes to determine transcriptomic variation between these cell types.
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5603
Platform:
GPL6884
10 Samples
Download data: TXT
Series
Accession:
GSE50704
ID:
200050704
5.
Full record GDS5603

Ventricular cardiomyocytes generated in vitro from embryonic stem cells

Analysis of ventricular cardiomyocytes derived from HES2 embryonic stem cells (hESC-VCMs). The in vivo counterparts (undifferentiated HES2 cells, fetal VCMs, and adult VCMs) were also examined. Results provide insight into molecular mechanisms underlying the developmental status of hESC-VCMs.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 4 cell type sets
Platform:
GPL6884
Series:
GSE50704
10 Samples
Download data
6.

Transcriptional Profiling of Human Embryonic Stem Cell-Derived Cardiomyocytes

(Submitter supplied) Myocardial infarction is a major cause of morbidity and mortality worldwide. The limited ability of the surviving cardiac cells to proliferate following an ischemic attack renders the damaged heart susceptible to unfavorable remodeling processes and heart failure. Currently, pharmaceutical and implantable device management of heart failure seek only to preserve existing viable myocardium after an ischemic attack, and thus merely slows the progression of cardiac dysfunction. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS3513
Platform:
GPL4133
16 Samples
Download data: TXT
Series
Accession:
GSE13834
ID:
200013834
7.
Full record GDS3513

Embryonic stem cell-derived cardiomyocytes

Analysis of cardiomyocytes (CMs) derived from embryonic stem cells (ESCs). Under the appropriate conditions, ex vivo ESCs can differentiate into beating cardiomyocytes via an embryoid body (EB) intermediate. Results provide insight into the mechanisms underlying the differentiation of ESC into CMs.
Organism:
Homo sapiens
Type:
Expression profiling by array, log10 ratio, 4 cell type sets
Platform:
GPL4133
Series:
GSE13834
16 Samples
Download data: TXT
8.

Gene expression profiles of mouse ESC cardiomyocyte-specific differentiation

(Submitter supplied) The differentiation to cardiomyocytes is a prerequisite and an important part of heart development. A good understanding of the complicated cardiomyocyte differentiation process benefits cardiogenesis study. Embryonic stem cells (ESCs), cell lines with infinite ability to proliferate and to be differentiated into all cell types of the adult body, are important research tools for investigation of differentiation and meanwhile good models for developmental research. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6096
8 Samples
Download data: CEL, TXT
Series
Accession:
GSE58300
ID:
200058300
9.

miRNA profiling during cardiomyocyte-specific differentiation of murine embryonic stem cells based on two different miRNA array platforms

(Submitter supplied) miRNA plays a critical role in a wide variety of biological processes Profiling miRNA expression during the differentiation of embryonic stem cells will help us to understand the regulation pathway of differentiation, therefore to explain disease mechanisms and to find possible therapeutical targets. In this study miRNA expressions were profiled during cardiomyocyte-specific differentiation of murine embryonic stem cells with high-throughput microarray platforms. more...
Organism:
Mus musculus; synthetic construct
Type:
Non-coding RNA profiling by array
Platforms:
GPL8786 GPL10849
32 Samples
Download data: CEL, TXT
Series
Accession:
GSE24066
ID:
200024066
10.

Fatty Acids Promote the Maturation of Cardiomyocytes Derived from Human Pluripotent Stem Cells

(Submitter supplied) Although human pluripotent stem cells-derived cardiomyocytes (hPSC-CMs) have emerged as a novel platform for heart regeneration, disease modeling, and drug screening, their immaturity significantly hinders their application. A hallmark of postnatal cardiomyocyte maturation is the metabolic substrate switch from glucose to fatty acids. We hypothesized that fatty acid supplementation would enhance hPSC-CM maturation. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL16791
4 Samples
Download data: TXT
11.

Gene expression profilings in human embryonic stem cell-derived cardiomyocytes in vivo and in vitro

(Submitter supplied) RNA sequencing of human embryonic stem cell-derived cardiomyocytes
Organism:
Homo sapiens; Rattus norvegicus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL27452 GPL24676
16 Samples
Download data: CSV, TXT
Series
Accession:
GSE137255
ID:
200137255
12.

Up-regulation of JAK-STAT pathway promotes maturation of human stem cell-derived cardiomyocytes

(Submitter supplied) hPSC-CM has been used to model cardiac-related disease phenotypes. However, the immaturity of hPSC-CM constrains their potential in cell-based therapy, disease modeling and drug discovery. To understand the molecular mechanism driving human PSC-CM maturation, we utilized a metabolic reporter cell line that allows for the purification of CM that reflects different physiological status (fetal-like or matured). more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL20301
6 Samples
Download data: XLSX
13.

Neonatal Transplantation Confers Maturation of PSC-Derived Cardiomyocytes Conducive to Modeling Cardiomyopathy

(Submitter supplied) Pluripotent stem cell-derived cardiomyocytes (PSC-CMs) were transplanted into rats for one month to determine the change in morphology, structure, and function. Single cell RNA seq analysis was performed to compared the transcriptome of in vivo matured PSC-CMs to adult rat cardiomyocytes and in vitro cultured PSC-CMs.
Organism:
Rattus norvegicus; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL20084
24 Samples
Download data: CSV
Series
Accession:
GSE92247
ID:
200092247
14.

LIN28B is a barrier to the maturation of human embryonic stem cell derived pancreatic β cells

(Submitter supplied) Comparative RNA and small RNA sequencing analysis of in vitro differentiated β like cells, in vivo matured β cells, adult islet cells, and Lin28 deficient in vitro differentiated β like cells
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing
Platform:
GPL11154
24 Samples
Download data: TXT
15.

A distinct microRNA signature for definitive endoderm derived from human embryonic stem cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array; Expression profiling by array
Platforms:
GPL7363 GPL8733
29 Samples
Download data: CEL
Series
Accession:
GSE16690
ID:
200016690
16.

MicroRNA expression data from differentiation of human H9 ESCs into definitive endoderm on MEF feeder layers

(Submitter supplied) Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm (DE) is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung). We used microarrays to detail the changes in microRNA expression during the transition from pluripotent hESCs into definitive endoderm.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8733
6 Samples
Download data: CEL
Series
Accession:
GSE16689
ID:
200016689
17.

MicroRNA expression data from differentiation of human Cyt49 ESCs into definitive endoderm on MEF feeder layers

(Submitter supplied) Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung) We used microarrays to detail the changes in microRNA expression during the transition from pluripotent hESCs into definitive endoderm
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8733
6 Samples
Download data: CEL
Series
Accession:
GSE16687
ID:
200016687
18.

mRNA expression data from differentiation of human ESCs into definitive endoderm, Cyt49 on matrigel

(Submitter supplied) hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm (DE) is the first step into the pathway to endoderm derived tissues: pancreas, liver, gut, lung. We used microarrays to detail the changes in mRNA expression during the transition from pluripotent hESCs into definitive endoderm.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL7363
9 Samples
Download data: TXT
Series
Accession:
GSE16681
ID:
200016681
19.

MicroRNA expression data from differentiation of human Cyt49 ESCs into definitive endoderm in feeder-free conditions

(Submitter supplied) Pluripotent hESCs can differentiate into the three primary embryonic lineages (endoderm, mesoderm, ectoderm) as well as extraembryonic tissues. Definitive endoderm is the first step into the pathway to endoderm dreived tissues (pancreas, liver, gut, lung). We used microarrays to detail the changes in microRNA expression during the transition from pluripotent hESCs into definitive endoderm.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8733
8 Samples
Download data: CEL
Series
Accession:
GSE16678
ID:
200016678
20.

Transcriptional Landscape of Cardiomyocyte Maturation

(Submitter supplied) Decades of progress in developmental cardiology has advanced our understanding of the early aspects of heart development, including cardiomyocyte (CM) differentiation. However, control of CM maturation which is subsequently required to generate adult myocytes, remains elusive. Here, we analyzed over 200 microarray datasets from early embryonic to adult hearts and identified a large number of genes whose expression shifts gradually and continuously during maturation. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL1261
9 Samples
Download data: CEL
Series
Accession:
GSE73233
ID:
200073233
Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=|query=65|qty=5|blobid=MCID_67352773b31eac71f544f696|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center