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Links from GEO DataSets

Items: 14

1.

A gene signature in histologically normal surgical margins is predictive of oral carcinoma recurrence

(Submitter supplied) Samples were prospectively collected from patients with histologically normal surgical resection margins. 96 tissue samples (histologically normal margins, oral carcinoma and adjacent normal tissues) from 24 patients comprised the training set. Our study design was guided by the hypothesis that the expression of genes present in oral squamous cell carcinoma (OSCC) but not in healthy oral tissues would be indicative of recurrence in advance of histological alteration. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS4562
Platform:
GPL10526
96 Samples
Download data: CEL
Series
Accession:
GSE31056
ID:
200031056
2.
Full record GDS4562

Squamous cell carcinoma of the tongue: tumors and histologically normal surgical margins

Analysis of oral carcinoma, histologically normal margins, and adjacent normal tissues from patients with squamous cell carcinoma (OSCC) of the tongue (training set). Results provide insight into molecular signature in histologically normal margins that is predictive of oral carcinoma recurrence.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 2 disease state, 24 individual, 2 specimen, 20 tissue sets
Platform:
GPL10526
Series:
GSE31056
96 Samples
Download data: CEL
3.

Gene expression profiling of oral squamous cell carcinoma (OSCC)

(Submitter supplied) OSCC is associated with substantial mortality and morbidity. To identify potential biomarkers for the early detection of invasive OSCC, we compared the gene expressions of OSCC, oral dysplasia, and normal oral tissue from patients without oral cancer or preneoplastic oral lesions (controls). Results provided models of gene expression to distinguish OSCC from controls.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
229 Samples
Download data: CEL
Series
Accession:
GSE30784
ID:
200030784
4.

Oral Cavity Cancer Compared to Adjacent "Normal" Tissue [Validation Set]

(Submitter supplied) Oral Cavity Cancer
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
103 Samples
Download data: CEL
Series
Accession:
GSE42743
ID:
200042743
5.

A 13-gene signature prognostic of HPV-negative OSCC: discovery and external validation

(Submitter supplied) OSCC is associated with substantial mortality and morbidity. In this study, we built on our previous molecular work to identify and validate a prognostic 13-gene signature that showed a higher ability than tumor stage in predicting survival for patients with HPV-negative oral squamous cell carcinoma (OSCC).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
97 Samples
Download data: CEL
Series
Accession:
GSE41613
ID:
200041613
6.

MiRNA SIGNATURE FOR ORAL SQUAMOUS CELL CARCINOMA

(Submitter supplied) The present study is aimed at profiling the miRNA expression pattern in oral squamous cell carcinoma (OSCC) and adjacent oral mucosa to develop a new miRNA signature for oral cancer. Agilent Human miRNA Microarray v2.0 (G4470B, Agilent Technologies) was used to identify miRNAs differentially expressed in OSCC. MicroRNA processing was carried out according to the manufacturer’s instructions. Hybridized microarrays were scanned with a DNA microarray scanner (Agilent G2565BA) and features were extracted using the Agilent Feature Extraction (AFE) image analysis tool (version A.9.5.3) with default protocols and settings. more...
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL8227
48 Samples
Download data: TXT
Series
Accession:
GSE168227
ID:
200168227
7.

Expression and SNP array data for oral squamous cell carcinoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by SNP array; SNP genotyping by SNP array
Platforms:
GPL5175 GPL6801
201 Samples
Download data: CEL, CHP
Series
Accession:
GSE25104
ID:
200025104
8.

Affymetrix SNP array data for oral squamous cell carcinoma

(Submitter supplied) In order to identify biomarkers that contribute to genetic causes of OSCC, we attempt to identify copy number variation regions (CNV) in patients with OSCC. We identified and confirmed the clinical significance of amplification regions scattered from 8q22.2 to 8q24.3.
Organism:
Homo sapiens
Type:
Genome variation profiling by SNP array; SNP genotyping by SNP array
Platform:
GPL6801
122 Samples
Download data: CEL, CHP, TXT
Series
Accession:
GSE25103
ID:
200025103
9.

Validation of an expression signature for lymph node metastasis detection in oral cavity squamous cell carcinoma

(Submitter supplied) Validation of a previously established gene expression profile for detection of lymph node metastasis (ArrayExpress E-UMCU-11).
Organism:
Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL13953 GPL13952
316 Samples
Download data: TXT
Series
Accession:
GSE30788
ID:
200030788
10.

Prediction of lymphatic metastasis from primary squamous cell carcinoma of the oral cavity

(Submitter supplied) Metastasis via the lymphatics is a major risk factor in squamous cell carcinoma of the oral cavity (OSCC). We sought to determine whether the presence of metastasis in the regional lymph node could be predicted by a gene expression signature of the primary tumor. A total of 18 OSCCs were characterized for gene expression by hybridizing RNA to Affymetrix U133A gene chips. Genes with differential expression were identified using a permutation technique and verified by quantitative RT-PCR and immunohistochemistry. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS1062
Platform:
GPL96
27 Samples
Download data: CEL
Series
Accession:
GSE2280
ID:
200002280
11.
Full record GDS1062

Squamous cell carcinoma of the oral cavity with lymph node metastasis

Expression profiling of 18 primary squamous cell carcinomas of the oral cavity with or without lymph node metastasis. Expression in lymph node metastasis also examined. Results used to identify gene expression signature in primary tumors that indicates the presence of lymph node metastasis.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state, 2 tissue sets
Platform:
GPL96
Series:
GSE2280
27 Samples
Download data: CEL
DataSet
Accession:
GDS1062
ID:
1062
12.

Expression profiling of Early Stage Lung Squamous Cell Carcinomas

(Submitter supplied) One hundred and seven lung Squamous Cell Carcinomas collected from early stage (stage I+II; AJCC 7th edition) patients at the National Cancer Center Hospital (Tokyo, Japan) between 1997 and 2008 were hybridized to the Human Transcriptome (HT) Array 2.0
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17586
107 Samples
Download data: CEL
Series
Accession:
GSE74777
ID:
200074777
13.

Expression data from 57 patients with oral cancer and 22 normal persons

(Submitter supplied) In order to aid the development of patient-tailored diagnostics and therapeutics, we attempted to identify a genetic signature associated with disease prognosis in OSCC. A genome-wide analysis of transcription with the Affymetrix GeneChip Human Gene 1.0 ST Array was conducted. In this dataset, we include the expression data obtained from 57 specimens from patients with OSCC and 22 oral tissues from normal persons.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL5175
79 Samples
Download data: CEL
Series
Accession:
GSE25099
ID:
200025099
14.

Comparative analysis of mouse oral cancer cell lines

(Submitter supplied) A comparative microarray analysis of indolent or aggressive mouse oral cancer cell lines was performed to identify gene expression signatures and specific molecules involved in aggressive tumor growth.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6885
24 Samples
Download data: TXT
Series
Accession:
GSE50041
ID:
200050041
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