Similar studies for GEO DataSets (Select 200010244) - GEO DataSets

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Items: 20

Select item 2000102441.

(Submitter supplied) Transcriptome response of the yeasts C. glabrata and S. cerevisiae treated by an antifungal agent, benomyl Keywords: time course; stress response

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Expression profiling by array

Platforms:: GPL6384 GPL6388
12 Samples

Download data: TXT

Series

Accession:: GSE10244

ID:: 200010244

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000978012.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platforms:: GPL22622 GPL13821
62 Samples

Download data: WIG

Series

Accession:: GSE97801

ID:: 200097801

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Select item 2000978003.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla RNA-seq]

(Submitter supplied) In S. cerevisiae, the phosphate starvation (PHO) responsive transcription factors Pho4 and Pho2 are jointly required for induction of phosphate response genes and survival in phosphate starvation conditions. In the related human commensal and pathogen C. glabrata, Pho4 is required but Pho2 is dispensable for survival in phosphate-limited conditions and is only partially required for inducing the phosphate response genes. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22622
8 Samples

Download data: CSV

Series

Accession:: GSE97800

ID:: 200097800

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000977994.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer RNA-seq]

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL13821
36 Samples

Download data: CSV

Series

Accession:: GSE97799

ID:: 200097799

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000977985.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Cgla ChIP-seq]

Organism:: Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL22622
9 Samples

Download data: WIG

Series

Accession:: GSE97798

ID:: 200097798

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 2000977976.

Evolution of Reduced Co-Activator Dependence Led to Target Expansion of a Starvation Response Pathway [Scer ChIP-seq]

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13821
9 Samples

Download data: WIG

Series

Accession:: GSE97797

ID:: 200097797

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Select item 2000229397.

Comparative transcriptome profiling analyses during the lag phase uncover YAP1, PDR1, PDR3, RPN4 and HSF1 as key regulatory genes in genomic adaptation to the lignocellulose derived inhitibor-stress for saccharomyces cerevisiae

(Submitter supplied) The yeast Saccharomyces cerevisiae is able to adapt and in situ detoxify lignocellulose derived inhibitors such as furfural and HMF. The length of lag phase for cell growth in response to the inhibitor challenge has been used to measure tolerance of strain performance. Mechanisms of yeast tolerance at the genome level remain unknown. Using systems biology approache, this study investigated comparative transcriptome profiling, metabolic profiling, cell growth response and gene regulatory interactions of yeast strains and selective gene deletion mutations in response to HMF challenges during the lag phase of growth. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL10684
14 Samples

Download data: GPR

Series

Accession:: GSE22939

ID:: 200022939

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000848168.

Candida glabrata WT and mutants under iron starvation

(Submitter supplied) Transcriptional time series of Candida glabrata under iron starvation (SD medium without Fe). Wild type and deletion mutants of the iron-related transcription factors Aft1 and Sef1, as well as of the iron uptake transporter Ftr1 as a positive control.

Organism:: Nakaseomyces glabratus; Nakaseomyces glabratus CBS 138

Type:: Expression profiling by array

Platform:: GPL10713
60 Samples

Download data: TXT

Series

Accession:: GSE84816

ID:: 200084816

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Select item 2000743619.

Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction With the Small Molecule iKIX1

(Submitter supplied) Eukaryotic transcription activators stimulate the expression of specific sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting Mediator complex. We previously identified an activator-targeted ~85 amino acid three-helix bundle KIX domain in the human MED15 Mediator subunit that is structurally conserved in Gal11 Mediator subunits in fungi. The Gal11 KIX domain is engaged by pleiotropic drug resistance transcription factor (Pdr1) orthologues, key regulators of the multidrug resistance (MDR) pathway in S. more...

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL17342 GPL21066
24 Samples

Download data: TXT

Series

Accession:: GSE74361

ID:: 200074361

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Select item 20014828810.

A new regulator in the crossroads of oxidative stress resistance and virulence in Candida glabrata: the transcription factor CgTog1

(Submitter supplied) The goals of this study are to compare C. glabrata transcriptome profiling (RNA-seq) upon exposure to hydrogen peroxide in order to assess the correspondent response. The role of the transcription factor Tog1 is clarified through comparison of the transcrptome profiles of WT and Tog1 mutant cells. mRNA profiles of WT and ∆tog1 were generated by deep sequencing, in duplicate, using Illumina HiSeq. The sequence reads that passed quality filters were analyzed with TopHat followed by HTSeq. more...

Organism:: Nakaseomyces glabratus

Type:: Expression profiling by high throughput sequencing

Platform:: GPL26394
8 Samples

Download data: TXT

Series

Accession:: GSE148288

ID:: 200148288

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Select item 20000176311.

Transcriptional effect of aft1 and aft2 mutation in iron depleted conditions

(Submitter supplied) The paralogous transcription factors Aft1p and Aft2p activate the expression of genes involved in iron metabolism under iron depleted conditions. Both are able to bind to the same DNA consensus sequence in vitro. We used DNA microarrays and loss of function mutant strains to better understand the respective roles of Aft1p and Aft2p in the regulation of gene expression Keywords: other

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL205
6 Samples

Download data

Series

Accession:: GSE1763

ID:: 200001763

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Select item 20007470012.

ChIP-Seq for Yrr1 protein on Saccharomyces cerevisiae cells carrying different YRR1 alleles in response to 4-nitroquinoline-N-oxide (4NQO)

(Submitter supplied) In this study, we constructed three isogenic strains of S96 yrr1Δ background (its native YRR1 gene was knocked out) carrying three different YRR1 alleles, YRR1_S96, YRR1_YJM789, YRR1_S96-I775E, respectively. We then conducted chromatin immuno-precipitation followed by high-throughput sequencing (ChIP-Seq) for Yrr1 protein on the three strains grown in Yeast Peptone Dextrose medium (YPD) and YPD + 4NQO.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL13821
24 Samples

Download data: XLSX

Series

Accession:: GSE74700

ID:: 200074700

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20007464213.

RNA-Seq of Saccharomyces cerevisiae cells carrying different YRR1 alleles in response to 4-nitroquinoline-N-oxide (4NQO) and to glycerol as the sole carbon source

(Submitter supplied) In this study, we constructed three isogenic strains of S96 yrr1Δ background (its native YRR1 gene was knocked out) carrying three different YRR1 alleles, YRR1_S96, YRR1_YJM789 and YRR1_S96-I775E, respectively. We then conducted RNA deep sequencing (RNA-Seq) on the three strains grown in Yeast Peptone Dextrose medium (YPD), YPD + 4NQO and Yeast Peptone glycerol medium (YPglycerol).

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by high throughput sequencing

Platform:: GPL17143
18 Samples

Download data: XLSX

Series

Accession:: GSE74642

ID:: 200074642

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Select item 20000764514.

Expression data for Saccharomyces cerevisiae oxidative stress response

(Submitter supplied) Oxidative stress is a harmful condition in a cell, tissue, or organ, caused by an imbalnace between reactive oxygen species and other oxidants and the capacity of antioxidant defense systems to remove them. The budding yeast S. cerevisiae has been the major eukaryotic model for studies of response to oxidative stress. We used microarrays to study the genome-wide temporal response of the yeast S. cerevisiae to oxidative stress induced by cumene hydroperoxide. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Dataset:: GDS3035
Platform:: GPL90
48 Samples

Download data: CEL

Series

Accession:: GSE7645

ID:: 200007645

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 303515.

Saccharomyces cerevisiae response to oxidative stress: time course

Analysis of Saccharomyces cerevisiae cultures at various time points up to 120 minutes following treatment with the oxidant cumene hydroperoxide (CHP). Results provide insight into molecular mechanisms underlying the response of the yeast S. cerevisiae to oxidative stress.

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array, transformed count, 2 agent, 8 time sets

Platform:: GPL90
Series:: GSE7645
48 Samples

Download data: CEL

DataSet

Accession:: GDS3035

ID:: 3035

PubMed Full text in PMC Similar studies GEO Profiles Analyze DataSet

Select item 20008985416.

BY4741 and BY4741（Δyrr1）transcriptional differences under vanillin stress

(Submitter supplied) BY4741（Δyrr1）exhibited better vanillin tolerance to vanillin than that of wildtype strain. To assess transcriptional differences between these two strains. Yrr1p is a transcriptional factors which activated genes related to multidrug resistance.The transcriptome of BY4741 and BY4741（Δyrr1）under vanillin stress or vanillin free conditions were conducted,respectively

Organism:: Saccharomyces cerevisiae BY4741

Type:: Expression profiling by high throughput sequencing

Platform:: GPL22674
8 Samples

Download data: TXT

Series

Accession:: GSE89854

ID:: 200089854

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20002357717.

Nucleosome positioning for 4 yeast species

(Submitter supplied) We describe the genome-wide nucleosome profiles of four related yeast species. All species display the same global organization features first described in S. cerevisiae: a stereotypical nucleosome organization along genes, and the classification of promoters into these which contain or lack a pronounced Nucleosome Depleted region (NDR), with the latter displaying a more dynamic pattern of gene expression. more...

Organism:: Saccharomyces cerevisiae; Saccharomyces bayanus; Saccharomyces kudriavzevii; Nakaseomyces glabratus

Type:: Genome binding/occupancy profiling by high throughput sequencing

4 related Platforms
4 Samples

Download data: TXT

Series

Accession:: GSE23577

ID:: 200023577

PubMed Full text in PMC Similar studies SRA Run Selector

Select item 20007582818.

HAL2 overexpression induces iron acquisition and enhanced salt resistance in bdf1Δ

(Submitter supplied) The strain bdf1Δ+HAL2 improved salt resistance of bdf1∆. To gain further insight into the mechanism of bdf1∆ salt sensitivity, DNA microarray analysis was performed to determine the reason for the salt sensitivity of bdf1∆ cells and the process of how HAL2 overexpression and HDA1 deletion improves salt resistance. Transcriptomic analysis under salt treatment (0.5 mol.L-1 NaCl for 45 min) was performed using four different strains: bdf1∆, W303, bdf1Δ+HAL2 and bdf1∆hda1∆. more...

Organism:: Saccharomyces cerevisiae

Type:: Expression profiling by array

Platform:: GPL17201
5 Samples

Download data: TXT

Series

Accession:: GSE75828

ID:: 200075828

Select item 20001062219.

Transcription Factor Substitution during the Evolution of Fungal Ribosome Regulation

(Submitter supplied) Coordinated ribosomal protein (RP) gene expression is crucial for cellular viability, but the transcriptional network controlling this regulon has only been well characterized in the yeast Saccharomyces cerevisiae. We have used whole-genome transcriptional and location profiling to establish that, in Candida albicans, the RP regulon is controlled by the Myb-domain protein Tbf1 working in conjunction with Cbf1. more...